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    The neuropsychological and neurophysiological profile of women with pseudoseizure
    (W B Saunders Co-Elsevier Inc, 2013) Almis, Behice Han; Cumurcu, Birgul Elbozan; Unal, Suheyla; Ozcan, A. Cemal; Aytas, Ozgur
    Objective: Our aim in this study was to compare the assessments of neuropsychological tests and the p50 neurophysiological test of patients with seizure diagnosed as conversion disorder and healthy control subjects, and to investigate the neurological status in conversion disorder with pseudoseizure. Methods: A total of 22 female conversion disorder patients with convulsions diagnosed according to SCID-I/CV and 22 healthy women were included in the assessment. The participants were administered WMS-R, the cancellation test, and the Stroop test as neuropsychological tests and p50 was assessed as a neurophysiological test. Results: The patient's results for the neuropsychological tests were found to be significantly low compared to the control group. The p50 sensory gating ratios of the patient group were statistically significantly lower than the controls. There was no significant correlation between the neuropsychological test scores and gating ratios of the patient and control groups. Conclusions: This study is the first to check sensory gating in conversion disorder patients with pseudoseizure and its most important result is finding reduced p50 sensory gating in patients. Our results suggest that these patients have a neurological tendency to this disease due to functional neurophysiological features. (C) 2013 Elsevier Inc. All rights reserved.
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    Rabbit syndrome: Developed after increasing the dosage of quetiapine in a patient using quetiapine with duloxetine
    (Kure Iletisim Grubu A S, 2011) Cumurcu, Birgul Elbozan; Almis, Behice Han; Kartalci, Sukru; Karlidag, Rifat
    Rabbit syndrome: Developed after increasing the dosage of quetiapine in a patient using quetiapine with duloxetine Fifty-six years old, female patient who was being followed and treated for resistant depression, had been using duloxetine 60 mg/day and quetiapine 300 mg/day for 3 months. After 2 weeks the quetiapine dose was increased to 600 mg/day because of resistant depression concomitant with insomnia. A movement disorder was observed, appearing as a rhythmic tremor in the perioral muscles which was defined by the patient as involuntary. This involuntary rhythmic perioral tremor was diagnosed as rabbit syndrome and for this reason quetiapine, the only antipsychotic used by the patient, was gradually decrease in dose and eventually stopped. Four weeks after stopping the quetiapine, the patient's involuntary perioral rhythmic movements decreased from four to zero points, according to the lips and perioral subgroup of the Abnormal Involuntary Movements Scale (AIMS).