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    Attention deficit and hyperactivity symptoms in adult migraine patients
    (2019) Alpua, Murat; Say, Bahar; Turgut, Esra; Ergun, Ufuk; Visal Buturak, Sadiye
    Aim: To screen the symptoms of attention deficit and hyperactivity disorder in adult migraine patients. Material and Methods: Our study included 102 migraine patients and 93 sex- and age-matched healthy volunteers. Gender, age, level of education and duration of disease were recorded. We used the adult attention deficit/hyperactivity disorder self-report scale to evaluate the symptoms of adult attention deficit / hyperactivity disorder. In addition, the short form-36 and the hospital anxiety and depression scale were applied to the patients and the healthy controls. Results: The mean scores of attention deficit hyperactivity disorder were significantly higher in migraine patients compared to the control group. There was no significant relationship between the Adult Attention Deficit and Hyperactivity Disorder Self-Report Scale scores and the duration of the disease. There was a negative correlation between the SF-36 health questionnaire scores and the Adult Attention Deficit and Hyperactivity Disorder Self-Report Scale scores. There was a positive correlation between the Migraine Disability Assessment scores, the number of migraine attacks and the Adult Attention Deficit and Hyperactivity Disorder Self-Report Scale scores. Conclusion: Attention-deficit and hyperactivity symptoms can develop in adult migraine patients and cause psychosocial morbidity and poor quality of life.
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    Is there any association between microalbuminuria and Parkinson’s disease?
    (2019) Alpua, Murat; Kisa, Ucler
    Aim: To investigate microalbuminuria in patients with Parkinson’s disease (PD) and to determine its relationship with the stages of the disease. Parkinson’s disease (PD) is a chronic neurodegeneration of dopaminergic neurons in the substantia nigra. The reason for the death of these neurons is still unclear; however, studies have demonstrated the potential involvement of mitochondria, endoplasmic reticulum in contributing to cellular oxidative stress.Material and Methods: Thirty-two PD patients who admitted to Neurology Clinic of Kirikkale University’s Medical Faculty and 30 healthy volunteers whose age and sex-matched were included in the study. Urine creatinine and urine albumin levels were determined in patient and healthy groups. The disease duration and Hoehn and Yahr stages were recorded.Results: There was no statistically significant difference between urine creatinine, microalbumin, and urine creatinine/albumin ratios when PD patient results compared with the healthy volunteers’. There was no significant correlation among urine creatinine, microalbumin, and urine creatinine/albumin ratio between the disease duration and Hoehn and Yahr staging in patients with PD.Conclusion: Microalbuminuria is an indirect finding of oxidative stress in urine. In the current study, microalbuminuria was not detected in PD patients at various stages of the disease. It is an important finding that microalbuminuria, a marker of oxidative stress in the urine in PD, a disease in which oxidative stress plays a significant role in etiopathogenesis, is not found.Keywords: Hoehn and Yahr Scale;microalbumin; oxidative stress; Parkinson’s disease; Urine creatinine.