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    The effect of Hypericum Perforatum on wound healing of oral mucosa in diabetic rats
    (Istanbul Univ Press, Istanbul Univ Rectorate, 2018) Altan, Ahmet; Aras, Mutan Hamdi; Damlar, Ibrahim; Gokce, Hasan; Ozcan, Oguzhan; Alpaslan, Cansu
    Purpose This study aims to investigate the histopathological and biochemical effects of the topical application of Hypericum perforatum on the healing of surgical wounds created in the oral mucosa of rats with experimentally induced diabetes mellitus. Materials and methods The study was carried out on 48 adult male Wistar albino rats. The animals were divided into two main groups as control and study groups. Two main groups were divided into three subgroups according to the sacrification days. All rats were given streptozotocin 60 mg/kg, after 72 hours, and those having blood glucose levels above 200 mg/dL were included in the study. Mucosal defects were created in the palatal area of the rats. H. perforatum oil was applied topically twice a day to the wounds of the rats in the study group. Animal were sacrificed on the 3rd, 7th and 10th days and samples taken from the palatal wounds were examined histologically and biochemically. Results On the 7th day, ulceration, necrosis, epithelialization, polymorphonuclear leucocytes and hydroxyproline variables showed statistically significant differences (p<0.05). Ulceration, necrosis and polymorphonuclear leukocytes values were higher in the control group, whereas epithelialization and hydroxyproline values were found to be higher in the H. perforatum group. Among 10th-day groups, there was only a statistically significant difference between the values of hydroxyproline, whereas H. perforatum-treated group showed high hydroxyproline levels (p<0.05). Conclusion Topically applied H. perforatum did not create any difference on the 3rd day, but it has positively affected the wound healing on the 7th and 10th days in diabetic rats.
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    The relationship between dentistry and forensic medicine
    (2020) Altan, Ahmet; Cetin, Selcuk; Altan, Halenur; Akbulut, Nihat
    Aim: The study aimed to have an idea about which subjects the relationship between dentistry and forensic medicine focuses on.Material and Methods: In the study, the consultation forms of the patients who were referred from Tokat Gaziosmanpaşa University, Medical Faculty, Forensic Medicine Department to Tokat Gaziosmanpaşa University, Faculty of Dentistry, Oral and Maxillofacial Surgery Department were examined. The forms of the patients admitted between January 2014, and January 2019 were analyzed. Demographic information such as gender, age, and the reasons for consultation was obtained from these forms.Results: In this retrospective study, the consultation forms of sixty-three patients were examined. The reasons for consultation of patients were determined as age estimation (n=32, 50.8%), trauma (n=30, 47.6%) and malpractice (n=1, 1.6%). In patients who were exposed to trauma, physical assault (n=17, 56.7%), traffic accident (n=5, 16.7%), falling (n=2, 6.7%), and firearm injuries (n=1, 3.3%) were among causes of trauma. In the trauma cases, the hard tissues affected in the maxillofacial region were teeth (n=14, 46.7%), symphysis mandible (n=3, 10%), mandibular condyle (n=2, 6.6%) and angulus mandible (n=2, 6.6%). The gender distribution of the patients with age estimation is examined; it is seen that the great majority of them were women (n=30, 93.75%). Furthermore, it is seen that age determination is mostly needed between 15-20 years of age (n=27, 84.4%).Conclusion: A dentist can be appointed as an expert for forensic events in professional life. Therefore, the dentist should pay attention to the training on judicial examination and approach to forensic cases.