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Öğe Can the patient-reported outcome instruments determine disease activity in rheumatoid arthritis?(Aepress Sro, 2011) Durmus, B.; Altay, Z.; Baysal, O.; Ersoy, Y.; Erdal, A.; Cevik, R.; Ardicoglu, O.Objectives: The aim of this study was to investigate the indicative value of the patient-reported outcome instruments (PROs) on disease activity in rheumatoid arthritis (RA). Methods: Three hundred sixty eight patients with RA were included in this cross-sectional study. Disease activity was evaluated using both the Disease Activity Score 28 (DAS 28) and the Clinical Disease Activity Index (CDAI). Patients who had DAS 28 score <3.60 points and CDAI score <10.00 points were allocated into the low disease activity group and those who had DAS 28 score >= 3.60 points and CDAI score >= 10.00 points into the moderate or high disease activity group. The Health Assessment Questionnaire (HAQ), Nottingham Health Profile (NHP), Rheumatoid Arthritis Quality of Life (RAQoL), and Short Form 36 (SF 36) were used as PROs. Logistic regression analysis was used to find variables, which had an indicative value for disease activity. Results: HAQ, pain and emotional reaction subscales of NHP, and bodily pain, general health and social functioning subscales of SF 36 had independent indicative values, when DAS 28 was used as dependent variable. On the other hand, HAQ, pain and emotional reaction subscales of NHP, and general health and emotional role limitation subscales of SF 36 had indicative values when CDAI was used as dependent variable. DAS 28 and CDAI both showed HAQ as the parameter with the highest odds ratio (OR). But RAQoL had shown no independent indicative value for projecting disease activity. Conclusion: It was concluded that HAQ could determine disease activity in RA better than other PROs included in this study (Tab. 4, Ref. 36). Full Text in free PDF www.bmj.sk.Öğe Comparison of three conservative treatment protocols in carpal tunnel syndrome(Wiley, 2006) Baysal, O.; Altay, Z.; Ozcan, C.; Ertem, K.; Yologlu, S.; Kayhan, A.The aim of this study was to investigate and compare the therapeutic effect of three different combinations in the conservative treatment of carpal tunnel syndrome (CTS) by means of clinical and electrophysiological studies. The combinations included tendon- and nerve-gliding exercises in combination with splinting, ultrasound treatment in combination with splinting and the combination of ultrasound, splinting, tendon- and nerve-gliding exercises. A total 28 female patients (56 wrists) with clinical and electrophysiologic evidence of bilateral CTS were studied. In all patient groups, the treatment combinations were significantly effective immediately and 8 weeks after the treatment. The results of the long-term patient satisfaction questionnaire revealed that symptomatic improvement is more prominent in the group treated with splinting, exercise and ultrasound therapy combination. Our results suggest that a combination of splinting, exercise and ultrasound therapy is a preferable and an efficacious conservative type of treatment in CTS.Öğe Gain in visual acuity after cataract surgery improves postural stability and mobility(Comenius Univ, 2011) Durmus, B.; Emre, S.; Cankaya, C.; Baysal, O.; Altay, Z.Objectives: Vision plays an important role in postural stability. It has also been shown that visual information from the environment and visual cues significantly contribute to balance skills. The aim of this study was to investigate the effects of visual acuity on postural stability and mobility before and after cataract surgery. Methods: The study group was composed of 25 male and 11 female patients (age 57-84, mean 66.6+/-4.7) who had been operated for age-related cataract. Postural stability and mobility were assessed before and four weeks after the surgery by means of Biodex stability system (BSS), Tinetti, Time up and go (TUG) and Functional reach (FR) tests, as well as by gait analysis (gait velocity, step length, step width, cadence, stride length). Results: Postoperative visual acuity was significantly improved. Gait velocity and cadence increased significantly but step length, stride length, and step width did not change significantly. Postoperative improvement of Tinetti balance, TUG and FR tests were significant. Similarly, antero-posterior stability index (APSI), medio-lateral stability index (MLSI) and overall stability index (OSI) that were examined with BSS improved significantly after the cataract surgery. Conclusion: These results demonstrated that gain in visual acuity after cataract surgery improves the postural stability and mobility of patients (Tab. 2, Fig. 1, Ref. 29). Full Text in free PDF www.bmj.sk.Öğe QUALITY OF LIFE, QUALITY OF SLEEP AND PRESENCE OF RESTLESS LEG SYNDROME IN ANKYLOSING SPONDYLITIS(Bmj Publishing Group, 2020) Zontul, S.; Cengiz, A. K.; Altay, Z.[Abstract Not Available]Öğe Vitamin D and muscle strength, functional ability and balance in peritoneal dialysis patients with vitamin D deficiency(Dustri-Verlag Dr Karl Feistle, 2011) Taskapan, H.; Baysal, O.; Karahan, D.; Durmus, B.; Altay, Z.; Ulutas, O.25(OH)D deficiency has been associated with significantly worse physical performance in individuals with normal renal function. We examined the physical function, muscle strength and balance in age- and gender-matched 25 Stage 3 - 4 CKD patients and 47 Stage 5 CKD patients on peritoneal dialysis (PD) with vitamin D deficiency by objective methods and evaluated the effect of vitamin D replacement on physical performance tests: the timed up and go (TUG) test, gait velocity test, timed chair stand test, stair climb test, dynamic balance tests (TUG test, dynamic postural stability test), static balance test (functional reach test) and muscle strength in these two groups. At baseline 25(OH) D in the Stage 3 - 4 CKD patients and patients on PD were 6.9 +/- 3.5 ng/ml (17.2 +/- 8.7 nmol/l) and 5.7 +/- 3.3 ng/ml (14.2 +/- 8.2 nmol/l), respectively (p > 0.05). Mean (+/- SD) 25(OH)D in Stage 3 - 4 CKD patients and those on PD were 52.0 +/- 40.9 ng/ml (129.7 +/- 102.2 nmol/l) and 41.9 +/- 21, ng/ml (104,5 +/- 52,6 nmol/l) respectively after vitamin D replacement (p > 0.05). When both Stage 3 - 4 CKD and dialysis patients became vitamin D-sufficient after vitamin D replacement, they took a significantly shorter time to complete the TUG test, gait velocity test, the timed chair stand test and stair climb test. Results of physical performance tests, static and dynamic balance tests and isometric strength tests improved in both groups after the treatment (p < 0.05). In conclusion, our results show that vitamin D supplementation improves muscle strength, functional ability and balance in both CKD and dialysis patients.
