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    Exposure to SO2 does not have a chronic effect on pulmonary functions of apricot workers
    (Taylor & Francis Ltd, 2010) Ermis, Hilal; Gokirmak, Munire; Yildirim, Zeki; Yologlu, Saim; Ankarali, Handan
    The authors have previously demonstrated that apricot sulfurization workers develop asthma-like syndrome during apricot sulfurization due to exposure to sulfur dioxide (SO2) gas. The aim of the current study was to demonstrate if exposure to SO2 gas had any chronic effects on pulmonary functions and bronchial reactivity of the workers. Twenty-five apricot sulfurization workers and a control group were included in the study. Physical examination, skin prick tests, pulmonary function tests (PFTs), and bronchoprovocation tests (BPTs) were performed before and after the season of sulfurization in the worker group. Skin prick tests, PFTs, and BPTs were performed also in the control group without a history of exposure to SO2 gas. There was no statistically significant difference between PFT and BPT results of the workers and the control group. Comparison of the PFT results of the workers before and after the season of apricot sulfurization neither reveal a significant difference. Four (16%) out of 25 workers were positive for BPTs before the period. Only one worker who had a negative BPT result before the sulfurization season was positive afterwards. The lack of a chronic effect on pulmonary functions is consistent with the diagnosis of asthma-like syndrome in apricot sulfurization workers.
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    The importance of torg ratio in patients with ankylosing spondylitis
    (2018) Bakirci, Sinan; Ataoglu, Safinaz; Pasin, Tugce; Ankarali, Handan
    Aim: Ankylosing spondylitis is a disease of unknown etiology. It is an inflammatory, rheumatic disease basically influencing peripheral articulations and extra-articular structures. It is chronic and it leads to deformities in vertebra. Deformities in vertebras may lead to cervical spinal stenosis in long term that may result in cervical myelopathy which is a serious health disorder. One of the methods to evaluate the diameter of cervical canal is Torg ratio. Materail and Methods: In this study, patients with ankylosing spondylitis for more than 10 years have been examined through lateral cervical radiograms. The patients were both male and female whose ages range from 40-50 to 50-60. Morphometric measurements of cervical vertebras were made digitally and the differences between groups were revealed. Results: Considering the percentages of the narrowest cervical spinal canal diameter (CSCD) from anterior to posterior, it was seen that females have the highest vertebra levels in C4 and C6 whereas males have the highest vertebra levels in C3 and C7. The difference between males and females was found statistically significant (P=0.021). Minimum Torg ratio vertebra levels for females was in C6 for the age group 40-50 while it was C7 for the age group 50-60. As for the males, both age groups’ Torg ratio vertebra levels was minimum in C7. Conclusions: In this sense, it was concluded that patients with ankylosing spondylitis for more than 10 years should be monitored more carefully for neurological deficits that stem from cervical myelopathy.
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    α-Galactosidase levels in irritable bowel syndrome subtypes and quality of life of patients
    (2021) Soysal, Tuba; Ermis, Fatih; Ankarali, Handan
    Aim: There is a requirement for a reliable serologic marker that can be used for the diagnosis of Irritable Bowel Syndrome (IBS). The aim of our study was to research whether serum levels of Alpha-galactosidase (AG) is associated with IBS and to assess quality of life (QOL) of IBS patients. Materials and Methods: 110 adult patients who were diagnosed with IBS were evaluated. 90 patients and 25 healthy volunteers were included. Patients were classified into subtypes: IBS-Diarrhea (IBS-D), IBS-Constipation (IBS-C), IBS-Mixed (IBS-M), and 30 patients were enrolled for each group. We administered the Short Form 36 (SF-36) to participants to evaluate QOL. Serum AG levels of participants was determined. Results: The mean AG levels of IBS-C and control group were significantly lower than the other groups (p<0.05). The SF-36 questionnaire scores, except for the vitality and mental health domains, were higher significantly in the control group compared to IBS patients (p<0.05). The mean scores of IBS subtypes were similar. In addition, the mean physical functioning score of the control group was higher in comparison with the IBS-D group significantly (p<0.05). Conclusion: Our study has shown that IBS impairs QOL in patients. In addition, we suggest that future studies needed for the role of AG deficiency in IBS patients.