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Öğe Do elevated blood calcium levels in patients with peptic ulcer facilitate perforation?(İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi, 2018) Kahramanca, Şahin; Anuk, Turgut; Yıldırım, Ali CihatÖz:Aim: Calcium is primarily stored in bones in the body. The increase in blood calcium level due to primary or secondary causes leads to several impairments of the gastrointestinal system like nausea-vomiting, and peptic ulcer (PU). In this study, we want to compare and analyse the difference in blood calcium levels of patients who underwent surgery for peptic ulcer perforation (PUP) and were diagnosed with PU by endoscopy. Material and Methods: Between May 2012-January 2017, patients’ data for PU disease were recorded and our study was planned retrospectively. Patients were seperated into two groups: Group1, who was operated for PUP; and Group2, who were administered medical therapy for PU. Blood calcium levels during admission, age, gender and drug history of patients were recorded. Study exclusion criteria were patients whose data were missing (n=113), patients who had metabolic bone disease, patients who had been using calcium channel blockers and who were administered anti-ulcer drugs. Results: Twenty-eight patients had PUP and 176 patients had PU disease. Group 1 had a lower mean age (p=0.017), and higher male gender rate (p<0.001). The mean calcium level of Group 1 was 9.7±0.6 mg/dl, while the mean calcium level of Group 2 was 8.8±0.7 mg/dl (p<0.001). Less than the cut-off value of 9.25, calcium showed a sensitivity of 78.6% and a specificity value of 73.1% between groups. Conclusion: In our study, we found that in patients with PU diagnoses, elevated levels of calcium found in controls may increase both stomach acidity and the risk of PUPÖğe Do elevated blood calcium levels in patients with peptic ulcer facilitate perforation?(2018) Anuk, Turgut; Kahramanca, Sahin; Yildirim, Ali CihatAim: Calcium is primarily stored in bones in the body. The increase in blood calcium level due to primary or secondary causes leads to several impairments of the gastrointestinal system like nausea-vomiting, and peptic ulcer (PU). In this study, we want to compare and analyse the difference in blood calcium levels of patients who underwent surgery for peptic ulcer perforation (PUP) and were diagnosed with PU by endoscopy. Material and Methods: Between May 2012-January 2017, patients’ data for PU disease were recorded and our study was planned retrospectively. Patients were seperated into two groups: Group1, who was operated for PUP; and Group2, who were administered medical therapy for PU. Blood calcium levels during admission, age, gender and drug history of patients were recorded. Study exclusion criteria were patients whose data were missing (n=113), patients who had metabolic bone disease, patients who had been using calcium channel blockers and who were administered anti-ulcer drugs. Results: Twenty-eight patients had PUP and 176 patients had PU disease. Group 1 had a lower mean age (p=0.017), and higher male gender rate (p<0.001). The mean calcium level of Group 1 was 9.7±0.6 mg/dl, while the mean calcium level of Group 2 was 8.8±0.7 mg/dl (p<0.001). Less than the cut-off value of 9.25, calcium showed a sensitivity of 78.6% and a specificity value of 73.1% between groups. Conclusion: In our study, we found that in patients with PU diagnoses, elevated levels of calcium found in controls may increase both stomach acidity and the risk of PUPÖğe Evaluation of patients who have undergone unintentional parathyroidectomy following thyroidectomy: A retrospective cohort study(2018) Diken Allahverdi, Tulay; Binnetoglu, Kenan; Bayram, Harun; Anuk, Turgut; Bulut, UgurAim: We investigated the postoperative parathormone levels and the incidence of hypocalcemia in patients who had inadvertently underwent parathyroidectomy during thyroid surgery in this study. Material and Methods: We retrospectively evaluated a total of 142 patients who had undergone thyroidectomy between January 2011 and March 2017 from their charts. The demographic feature sand pathology diagnoses of the thyroidectomy patients were evaluated. The number of excised parathyroid glands in the pathology specimens and their location were determined. The PTH level was checked after surgery. Calcium was measured on the 2nd day. Results: The 142 patients consisted of 23 males (16.2%) and 119 females (83.8%). The mean age was 49.5 years. The surgery performed was bilateral total thyroidectomy in 131, bilateral subtotal thyroidectomy in 3, left total right subtotal thyroidectomy in 3, right total left subtotal thyroidectomy in 2, left thyroid lobectomy in 2, and complementary thyroidectomy in 1. Parathyroid tissue was found to have been excised during surgery in 35 patients, consisting of 33 females (94.2%) and 2 males (5.8%). The parathyroid tissue had been removed incidentally in 31 and not incidentally in 4. Conclusion: We found that some parathyroid glands had been inadvertently removed despite careful thyroid surgery.Öğe Factors influencing recurrence in inguinal herniorrhaphy(2018) Anuk, TurgutAbstract Aim: Inguinal herniorrhaphyis one of the operations made primarily in general surgery clinics. Here, factors influencing recurrence for patients on whom Lichtenstein tension free herniorrhaphy (LTFH) was administered in inguinal hernia surgery in our clinic were investigated. Material and Methods: From file records and operating room reports of patients on whom LTFH was administered with the diagnosis of inguinal hernia between May, 2012 and August, 2015. Age, gender, whether they were operated under emergency/elective conditions or not, body mass index (bmi), primary/recurrence conditions, direct/indirect/ pantaloon hernia typing, length of followup, recurrence rates, existence of scrotal component and calibre of internal ring were recorded. They were followed-up from 30 to 60 months. They were divided into two groups as the ones for whom recurrence was observed and not observed. Results: The recurrence was observed in 16 patients in their 46 (30-60) month- period of follow-up. It was determined that high values of body mass index influenced recurrence risk significantly (p<0.001). In patients operated under emergency/ elective conditions, no difference was determined between recurrence risks (p:0.105). When the common effect of the parameters examined, it was determined that BMI (p<0.001), width of internal ring calibr (p:0.002) and existence of direct hernia (p:0.002) increased risk of recurrence development independently of all other factors. Conclusion: It was determined that risk of recurrence had increased in patients with wide internal ring caliber and scrotal component, high BMI and who were especially operated because of recurrent inguinal hernia in follow-up periods following 48 months.
