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    Clinical and hormonal characteristics of women with various phenotypes of polycystic ovary syndrome
    (2020) Arda Duz, Senem; Tuncay, Gorkem; Karaer, Abdullah
    Aim: The goal of this study is to identify clinical and hormonal characteristics of women with various phenotypes of polycystic ovary syndrome. Material and Methods: One hundred seventy eight cases, between the ages 18-30, diagnosed with PCOS, up to Rotterdam criteria, in our clinic between February 2015 -November 2018 were recruited in this cross sectional study. Results: The number was declined 89 by using National Institutes of Health criteria, 132 up to Androgen Excess and PCOS Society criteria. 34.83% of the patients were phenotype A, 15.16% were phenotype B, 24.15% were phenotype C and 25.84% were phenotype D. When we compared the different phenotypes with each other, body mass index, fasting glucose, postprandial glucose, fasting insulin and homeostatic model assessment for insulin resistance were found to be higher in phenotype A. In addition, luteinizing hormone and luteinizing hormone to follicle stimulating hormone ratio was higher in phenotype D than in B and C. When multivariate analysis was performed, body mass index was found to be as a single statistically significant predictive factor on IR. Conclusion: Body mass index was the most effective factor on insulin resistance and the mean body mass index was significantly higher in phenotype A.
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    Comparison of umbilical coiling index in term pregnancies with and without fetal growth restriction
    (2022) Arda Duz, Senem; Cengiz, Murat; Tuncay, Gorkem; Karaca, Abdullah
    Abstract Aim: To investigate pregnancies with and without fetal growth restriction, giving birth after 37 weeks of gestation in terms of umbilical coiling index and neonatal outcomes. Materials and Methods: Twenty-nine patients with fetal growth restriction and 46 patients who have normal pregnancy and delivered after the 37th week of gestation were recruited in this study. The umbilical coiling index was measured by ultrasound, following the patients who were hospitalized for delivery. Results: There were statistically significant differences between the groups regarding to umbilical artery pulsatility index, gestational age at delivery and birth weight of the newborn. The need for a cesarean section because of non-reassuring fetal condition was statistically significantly higher in the fetal growth restriction group. The mean antenatal umbilical coiling index in fetal growth restriction and control patients was 0.29±0.08 and 0.27±0.08, respectively and the difference was not statistically significant. Conclusion: There was no statistically significant difference between the patients diag- nosed with and without fetal growth restriction who delivered after the 37th gestational week, regarding the umbilical coiling index and perinatal outcomes, except umbilical artery pulsatility index, gestational age at birth and birth weight of the newborn.