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    Comparison of the efficacy of extracorporeal shock wave therapy and trigger point dry needling in the treatment of Calcaneal Epin- A randomized trial
    (Sage Publications Inc, 2025) Arpaci, Muhammed Furkan; Dogru, Feyzi; Deniz, Mine Argali; Cicek, Ipek Balikci; Baykara, Rabia Aydogan; Erdem, Cumali; Tas, Ferhat
    Background: Dry needling (DN) and Extracorporeal shock wave therapy (ESWT) are common in calcaneal epin treatment. Objective The aim of the study was to compare the effects of both treatments on proprioception, balance, pain, and functional status. Methods: 90 patients which consist of 45 patients as DN + self stretching and 45 patients as ESWT + self stretching. Patients in each group were treated 1 session per week for 4 weeks. Assessments of 15 degrees ankle dorsiflexion and plantar flexion proprioception, one leg standing test (OLST), foot function index (FFI), visual analog scale (VAS) (first step, resting, activity), quality of life scale (SF-36) were performed. The outcomes were recorded at pre-treatment, post-treatment, and 4 weeks after the post-treatment. Results: Statistically significant differences were determined in VAS (resting, first step, activity) and FFI values in both treatment methods (p < 0.05). In OLST, SF-36, and FFI evaluations, DN was statistically more effective than the ESWT method (p < 0.001). In the 15 degrees proprioception evaluations, a significant difference was observed in the patient's ankle in both methods, while the DN method is more effective in the indicated stages of evaluation. Conclusions: Both methods applied to epin calcanei patients were effective, but the DN method is a more effective treatment method than the ESWT method in terms of balance, proprioception, foot function, and quality of life.
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    Correlation of Neuroanatomical Structures Related to Speech in Cerebral Palsy Patients Aged 0-17: A Retrospective MRI Study
    (Mdpi, 2025) Berk, Erhan; Uzumcuoglu, Rumeysa; Inceoglu, Feyza; Aydin, Merve; Arpaci, Muhammed Furkan; Sigirci, Ahmet; Pekmez, Hidir
    Background/Objectives: Cerebral Palsy (CP) is a non-progressive clinical condition characterized by secondary issues, including speech impairments. Our study aims to evaluate the volumes of brain areas related to speech in patients diagnosed with CP between the ages of 0-17. Methods: this study includes the images of 84 children: 42 in the control group who applied to the hospital between the specified dates and were reported as healthy by MRI from the patient records, and 42 patients with CP. Results: in the CP group, white and gray matter, cerebrum, cerebellum, thalamus, lobus frontalis, lobus temporalis, lobus parietalis, lobus insularis, gyrus cinguli, and nuclei basales volumes were observed to decrease statistically significantly compared to the control group (p < 0.001). Conclusions: we found a significant decrease in the volumes of speech-related brain areas in CP patients, indicating that CP can significantly impact the brain's speech-related regions.
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    Evaluation of the relationship between nasal septal deviation and development of facial asymmetry with anthropometric measurements depending on age
    (Elsevier Ireland Ltd, 2022) Arpaci, Muhammed Furkan; Ozbag, Davut; Aydin, Sukru; Senol, Deniz; Baykara, Rabia Aydogan; Cicek, Ipek Balikci
    Aim: It was aimed to determine the change of facial asymmetry resulting from nasal septal deviation (SD) depending on age, gender, degree of deviation and the affected area besides the effect of SD on somatotype and craniofacial morphology. Materials and methods: 171 volunteers (90 males, 81 females), 27 individuals aged 9-13, 44 individuals aged 14-18, 44 individuals aged 19-23 and 56 individuals in control group participated in the study conducted in otorhinolaryngology polyclinic.11 photometric, 16 anthropometric measurements were taken from the participants. Results: SD affects facial asymmetry formation, although not statistically significant compared to healthy individuals asymmetry rates (p>0.05). It was determined that the degree of SD affected asymmetry only between the ages of 14-18 (in adolescence) and the development of asymmetry in all SD patients was not statistically dependent on age and gender (p>0.05). Photometric measurements demonstrated asymmetries in horizontally-extending parameters of 1/3 middle part of face. There was no statistically significant difference in the cranial anthropometric measurements of the upper and lower 1/3 of the face compared to the control group (p>0.05). The order of the most asymmetrical parameters is Alare-Zygion, Alare-Subnasale, Cheilion-Gonion, Exocanthion-Cheilion, Midsagittal plane-Zygion, Zygion-Cheilion, Zygion-Gonion, Subalare-Cheilion, Glabella-Exocanthion. In all participants were determined that endomorph somatotype was dominant in female and mesomorph somatotype was dominant in male besides SD did not affect somatotype and somatotype did not alter with age. Conclusion: The development of facial asymmetry due to SD is not affected by age and gender furthermore SD does not affect craniofacial asymmetry and somatotype.
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    Investigation of the effects of radiotherapy and chemotherapy on brain volume in cancer patients: brain tumor study
    (Springer, 2026) Deniz, Birgul; Arpaci, Muhammed Furkan; Pekmez, Hidir; Uzun, Gokce Bagci; Inceoglu, Feyza; Harputluoglu, Hakan
    Purpose Brain tumors, characterized by the uncontrolled proliferation of abnormal cells within cerebral tissue, remain clinically challenging entities. Radiotherapy and chemotherapy constitute fundamental therapeutic modalities; however, their effects on healthy brain structures are not fully understood. This study aimed to evaluate the impact of these treatments on volumetric changes in brain structures and tumor size in patients with primary or metastatic brain tumors. Methods A retrospective cohort of 47 patients aged 18-90 years treated at Inonu University Turgut & Ouml;zal Medical Center between 2012 and 2023 was analyzed. Brain MRI scans were evaluated at three time points: pre-treatment, post-radiotherapy, and post-chemotherapy. Radiotherapy was delivered at a median dose of 60 Gy in 30-33 fractions, and temozolomide was used as the chemotherapy agent. Volumetric measurements of the telencephalon, diencephalon, ventricles, white matter, brainstem, cerebellum, and cerebral cortex were performed using MRICloud, while tumor volumes were quantified using the VolBrain platform. All volumetric differences were statistically tested using repeated-measures ANOVA with corresponding p-values reported. Results A statistically significant increase in telencephalon volume was observed after radiotherapy, followed by a return toward baseline measurements after chemotherapy. The diencephalon demonstrated a significant and persistent volume reduction following radiotherapy (p < 0.05). No statistically significant volumetric changes were identified in the ventricles, white matter, brainstem, cerebellum, or cerebral cortex (p > 0.05). Tumor volume changes were also statistically evaluated and showed no significant differences across the three time points (p = 0.456), indicating stable disease during the treatment course. Conclusion Radiotherapy and chemotherapy lead to region-specific volumetric alterations in the brain. The transient telencephalon enlargement is more likely attributable to treatment-related edema or inflammatory processes rather than functional improvement. The persistent diencephalon volume decline may reflect early treatment-related tissue vulnerability. Incorporating automated volumetric assessment into routine follow-up may support early detection of therapy-related structural changes and facilitate more personalized treatment planning.