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Öğe The Classification of Congenital Hand Abnormalities(2015) Koca, Tuba Tülay; Arslan, AydınÖğe Clinical features and follow-up results of the patients with methicillin-resistant Staphylococcus aureus (MRSA) in orthopedic practice(2018) Erdemir, Nuri; Korkmaz, Mehmet Fatih; Duman, Yücel; Arslan, Aydın; Sevimli, ReşitAbstract: Treatment of the infections caused by methicillin-resistant Staphylococcus aureus (MRSA) strains in orthopedic patients is a difficult and laborious process for both the patient and physician. Staphylococcus aureus(S. aureus) is one of the leading causes of community-acquired and nosocomial infections. In this study, we aimed to investigate the susceptibilityof the MRSA strainsisolated in orthopedic patients cultured for different reasons in our clinic to various antibiotics, and to evaluate clinical characteristics of the patients and factors affecting the prognosis. A total of 40 patients with MRSAisolated in our orthopedics clinic between December 2012 and November 2016 were retrospectively analyzed. Data including age, sex, comorbidities, previous surgeries, and previous antibiotic treatments were obtained from patients’ files and electronic information system. Of 40 patients, 60% were male, and 56% were over 60 years old. While 80% of the patients underwent an orthopedic surgery, 20% of them received no surgical intervention before the diagnosis. A total of 90% were in-patients, and the mean length of hospital stay was 22 days. The mean time from the date of hospitalization to the isolation of MRSA was 12 days. According to the consultation findings, in the clinical recovery process of the patients and in the treatment algorithm given to those patients, vancomycin and teicoplanin were found to be among the most important treatment options, in addition to significant debridement to be done, for MRSA strains. Our study results suggestthat, in addition to the surgical debridement, timely antibiotherapy is of utmost importance to reduce mortality and morbidity in MRSA-positive orthopedic patients.Öğe Comparison of different grafting techniques in open wedge high tibial osteotomy in terms of bone healing and functional outcomes(2018) Arslan, AydınAim: The aim of this study was to compare bone healing and functional outcomes of open wedge high tibial osteotomy (OWHTO) performed with different grafting techniques. Material and Methods: From January 2009 to March 2014, 132 patients (145 knees) were included in the study. Lysholm knee scoring scale was used in preoperative and postoperative clinical evaluation of patients. Patients were followed for at least 3 years. Clinical status of patients, time to bone union and complications were compared. Results: Autograft was used in 31 knees (29 patients), allograft in 43 knees (39 patients), hydroxyapatite in 71 knees (64 patients), respectively. The mean duration of bone union was 11.9 ± 3.6 (8-19) weeks in the autograft group, 13.1 ± 3.8 (10-25) weeks in the allograft group and 14.4 ± 4.9 (10-28) weeks in the hydroxyapatite group. The duration of bone union in autograft patients was significantly shorter than that in patients treated with hydroxyapatite. When the groups were evaluated in terms of delayed union, significantly high rates were found in allograft and hydroxyapatite groups when compared to the autograft group. (p<0.05) Significant improvement in clinical scores was observed in all groups postoperatively. Conclusion: In this study, autograft use was found to be more advantageous than hydroxyapatite and did not differ from allograft in terms of union time. The use of autograft was more advantageous than the other groups in terms of delayed union. There was no difference between groups with respect to nonunion. Functional and radiographic results were not different.Öğe The importance of red cell distribution width and neutrophillymphocyte ratio as a new biomarker in rheumatoid arthritis(2019) Koca, Tuba Tülay; Arslan, Aydın; Çiledağ Özdemir, Filiz; Berk, EjderAbstract: Objective: Rheumatoid arthritis (RA) is a long-lasting autoimmune disorder that primarily affects the joints.Various biomarkers have been used for the prognosis and clinical follow-up. There are few studies that haveinvestigated whether or not neutrophil-lymphocyte ratio (NLR) and red cell distribution width (RDW) are goodindicators of systemic inflammation. The present study aims to explore the prognostic value of RDW and NLRin rheumatoid arthritis (RA) as a new inflammatory marker.Methods: RA patients (n = 124) who presented to the Rheumatology outpatient clinic in our hospital betweenMarch 2015 and May 2015 were included in this study retrospectively. As a first group, 47 clinically activeRA patients who had high acute phase proteins were included. In the second group, 73 clinically in-remissionRA patients who had normal acute phase proteins were included. Fifty-five healthy volunteers constituted thecontrol group.Results: The mean RDW was found to be 15.2 ± 2.9 in the active group; 14.6 ± 2 in the inactive group and13.4 ± 1.4 in the control group (p < 0.01). The mean NLR was found to be 3.7 ± 2.2 in the active group; 3.7 ±1.6 in the inactive group and 3.2 ± 0.9 in the control group (p = 0.190). There were statistically significantdifferences between the RDW values of the active-period RA patients with the control group (p < 0.01). Therewas statistically significant difference between RDW values of active RA and inactive RA patients (p < 0.01).The NLR results between the RA group and the control group (p = 0.700); the active RA group, and the inactiveRA group (p = 0.169) were similar. There was not statistically difference between the NLR values of activeRA patients with the control group (p = 0.360). There was statistically difference between the NLR values ofinactive RA patients with the control group (p = 0.047).Conclusion: RDW was found higher in all RA group than control, additionally was also higher in active RAgroup than remission group. NLR values of remission group was higher than control.Öğe An investigation of infection rate and seasonal effect level in total joint replacement cases(2018) Arslan, Aydın; Görmeli, Gökay; Harma, Ahmet; Ertem, Kadir; Aslantürk, Okan; Sevimli, ReşitAbstract: This study aims at evaluating gender, age range and seasonal differences in patients who developed articular infection after undergoing joint prosthesis in our clinic. This study is a retrospective screening of advanced articular arthrosis patients who had undergone total joint arthroplasty of the upper and lower extremities between 2009 and 2016. Of 504 patients who had been treated with total joint replacement, our study includes 468 patients we could follow up or contact by phone and who had been applied 559 primary or revision total knee arthroplasty. The mean age of these patients was 58.9 (ranging from 41 to 74). We detected infection in 22 (3.9%) total joint arthroplasty patients. Of these 14 (63.63%) were females and 8 (36.36) were males. There was no statistically significant difference between infection rates in terms of seasonal distribution nor gender or age range. In the light of our findings, we concluded that gender, age range and seasonal differences have no effect on infection rates in total joint replacement cases.Öğe Open wedge high tibial osteotomy with sliding cancellous bone in distal fragment into the osteotomy gap; 2-year follow-up results(2020) Arslan, Aydın; Sevimli, ReşitAbstract: Open wedge high tibial osteotomy (OWHTO) has been performed by orthopedic surgeons without filling the osteotomy gap. However, the osteotomy space dimension and fixation methods suitable for this method are still controversial. We use the metaphyseal cancellous bone of tibia distal fragment; using a special technique to slide the cancellous bone into the osteotomy gap to provide better bone healing. This study was conducted to investigate the benefits of this method in terms of bone union. This was designed as a prospective randomized controlled study. There are 17 patients in each group. Patients with an osteotomy gap of only 12 mm were included in the study in preoperative planning. The Lysholm Knee Scoring Scale was used to assess the functional status of the patients. Hip Knee ankle (HKA) angle and tibial posterior slope angle were measured during preoperative and control visits. Bone healing was assessed by trabecular and cortical continuity on anteroposterior and lateral radiographs. Reduced pain and recovery of functions confirmed the union. The mean union time was 14.3 ± 4.7 (12-22) weeks in the control group and 13.1 ± 3.9 (11-18) weeks in the graft sliding group (P = 0.04). In the control group, the HKA angle was 10.8 ± 2.5 ° Varus preoperatively and 2.1 ± 1.4 ° valgus at second-year control visit. In the graft sliding group, preoperative HKA angel was found 11.3 ± 1.9 ° Varus and 2.7 ± 2.1 ° valgus at second-year control visit (p> 0.05). There was no statistically significant difference between the groups in terms of Lysholm Knee Scale scores at preoperative and postoperative second-year control visits. The sliding cancellous bone of the tibial distal fragment into the osteotomy gap provided earlier bone union than the control group. There was no difference in functional results between the groups in the two-year follow-up results of the patients.