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Öğe Sinus thrombosis: Clinical assessment(Turkish Society of Cerebrovascular Diseases, 2009) Kamişli Ö.; Arslan D.; Altinayar S.; Kamişli S.; Kablan Y.; Özcan C.Cerebral venous sinus thrombosis is a challenging condition because of its variability of clinical symptoms and signs. Diagnosis is not easy at initial presentation. All age groups can be affected. Large sinuses such as the superior sagittal sinus are most frequently involved. Systemic inflammatory diseases, inherited and acquired coagulation disorders are frequent causes, although in up to 30% of cases no underlying cause can be identified. The oral contraceptive pills appears to be an important additional risk factor. The spectrum of clinical presentations ranges from headache with papil oedema to focal deficit, seizures and coma. Magnetic resonance imaging with venography is the investigation of choice; computed tomography alone will miss a significant number of cases. Intravenous heparin is the first-line treatment for cerebral venous sinus thrombosis.
