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Öğe Added value of contrast-enhanced and diffusion-weighted MRI data sets for characterization of perianal fistulas; single center experience(2020) Aslan, SerdarAim: Our aim in this study is to determine the effectiveness of fat-suppressed T2-weighted (FS-T2W), FS-T2W+Diffusion-weighted image (DWI) and FS-T2W+Contrast-enhanced (CE) magnetic resonance imaging (MRI) data sets in the diagnosis of perianal fistula (PAF).Material and Methods: Retrospective analysis of 207 patients with a history of PAF operation between January 2018 and March 2020 was performed. The inclusion criteria were patients with PAF who underwent MRI prior to surgery and had a detailed intraoperative report. MRI data sets were evaluated by a radiologist, assessed fistula type, internal/external orifice position and presence of abscess/secondary tracts. The Cohen’s kappa (κ) statistic was used to define the level of between from intraoperative findings and MRI data sets agreement. The sensitivity and specificity were compared using the McNemar’s test.Results: All MRI data sets showed the presence of PAF correctly (n = 67, 100%). When the type of PAF per St James and AGA classification, presence of perianal abscesses/secondary tract agreement between intraoperative findings and MRI data sets is evaluated; moderate agreement for isolated FS-T2W data set, almost perfect agreement for combined FS-T2W+DWI and FS-T2W+CE data sets. In the evaluation of agreement for internal/external orifice position; substantial agreement for isolated FS-T2W data set, almost perfect agreement for combined FS-T2W+DWI and FS-T2W+CE data sets. Combined FS-T2W+DWI and FS-T2W+CE data sets have equal sensitivity and specificity each other (p = 0.544) and both data sets higher sensitivity and specificity than isolated FS-T2W data set (p 0.001, p 0.001, respectively).Conclusion: Adding DWI or CE data sets to the FS-T2W data set in the diagnosis of PAF has been shown to detect both diagnosis and complications with high accuracy. Combined FS-T2W+DWI and FS-T2W+CE data sets have equal sensitivity and specificity, and the use of the FS-T2W+DWI data set can prevent unnecessary use of contrast agent.Öğe Determination of acute appendicitis histologic subtypes by MDCT findings(2020) Aslan, Serdar; Ozturk, MesutAim: Our aim was to investigate if histological subtypes of acute appendicitis (AA) can be predicted by multidetector computed tomography (MDCT) and laboratory findings.Material and Methods: A retrospective search of the hospital database to identify patients who underwent appendectomy and had an abdominal MDCT scan and laboratory tests including white blood cell (WBC) count and c-reactive protein (CRP) available before the operation revealed 123 patients (mean age: 25.69 ± 17.23 years). Histopathological results were classified as mucosal, gangrenous and suppurative AA. MDCT scans of the patients were evaluated for appendix diameter, appendix wall thickness, presence of pericecal fluid and extraluminal air. The relationship between MDCT and laboratory findings and histological subtypes of AA were assessed.Results: There were 24 (19.5%) mucosal, 47 (38.2%) suppurative and 52 (42.3%) gangrenous AA. WBC count, CRP level, appendix wall thickness and appendix diameter was significantly different between mucosal and gangrenous AA (p 0.05) and between suppurative and gangrenous AA (p 0.05). However, there was no significant difference between mucosal and suppurative AA in terms of all variables (p = 0.752, 0.551, 0.756, 0.250 and 0.051, respectively). Presence of pericecal fluid was 92.2% sensitive and 93.1% specific for gangrenous AA. Presence of extraluminal air was 94.7% sensitive and 97.3% specific for gangrenous AA.Conclusion: AA histologic subtypes can be predicted by especially MDCT findings.Öğe Fatal systemic juvenile xanthogranuloma with multiple central nervous system lesions(2021) Bekci, Tumay; Aslan, Serdar; Cakir, Ismet Mirac; Bulut, MuhammetJuvenile xanthogranuloma (JXG) is a rare and benign proliferative disease of histiocytes (1). Its systemic form is rarer and while the condition is benign, prognosis is poor (1). Extra-cutaneous involvement of JXG can be seen in the eyes, lungs, liver, spleen, adrenals, gonads, kidneys, bowels, retroperitoneum, and rarely, central nervous system (CNS) (1,2). In current literature, systemic JXG cases with multiple CNS lesions with fatal outcome are very rare. The purpose of this case study is to present magnetic resonance imaging (MRI) findings of an 18-month-old patient with JXG who presented with multiple CNS lesions and later developed skin lesions. To the best of our knowledge, there are no reports in the literature of cases where skin lesions developed after presentation of isolated CNS lesions.Öğe The role of ARFI elastography to evaluate microstructrual changes of patients with testicular microlithiasis(Sage Publications Ltd, 2018) Aslan, Serdar; Bilgici, Meltem Ceyhan; Saglam, Dilek; Ozturk, MesutBackground: Testicular microlithiasis (TML) is thought to cause microstructural changes in the parenchyma of the testis, but it is difficult to demonstrate this by ultrasonography. It may be possible to evaluate microstructural changes in the testis by Acoustic Radiation Force Impulse (ARFI) elastography, which measures tissue stiffness. Purpose: To assess the tissue stiffness of testicles of children with TML and to compare them with the healthy control group. Material and Methods: Between November 2015 and May 2016, 25 pediatric patients with TML and 24 healthy children were enrolled in the study (mean age for TML and control group 6.7 +/- 3.17 and 7.9 +/- 4.18 years, respectively). Testicular volumes and mean shear wave velocity (SWV) values were calculated and compared with each other in both groups. Results: There was no significant difference in average testicular volumes between the TML group and the control group (1.14 cm(3), 1.21 cm(3), respectively; P = 0.986). Mean SWV of the testicles with TML and normal testicles with control group was 1.18 +/- 0.22 cm/s and 0.88 +/- 0.11 cm/s, respectively. The SWV of the testicles with TML was higher than the normal testicles and this was statistically significant (P < 0.001). Conclusion: This study has shown that tissue stiffness in patients with TML is increased compared to the normal population. ARFI elastography helps the early detection of microstructural changes in TML and can be used for screening and follow-up.Öğe The role of ARFI elastography to evaluate microstructrual changes of patients with testicular microlithiasis(Acta radıologıca, 2018) Aslan, Serdar; Bilgici, Meltem Ceyhan; Sağlam, Dilek; Öztürk, MesutBackground: Testicular microlithiasis (TML) is thought to cause microstructural changes in the parenchyma of the testis, but it is difficult to demonstrate this by ultrasonography. It may be possible to evaluate microstructural changes in the testis by Acoustic Radiation Force Impulse (ARFI) elastography, which measures tissue stiffness. Purpose: To assess the tissue stiffness of testicles of children with TML and to compare them with the healthy control group. Material and Methods: Between November 2015 and May 2016, 25 pediatric patients with TML and 24 healthy children were enrolled in the study (mean age for TML and control group 6.7 +/- 3.17 and 7.9 +/- 4.18 years, respectively). Testicular volumes and mean shear wave velocity (SWV) values were calculated and compared with each other in both groups. Results: There was no significant difference in average testicular volumes between the TML group and the control group (1.14 cm(3), 1.21 cm(3), respectively; P = 0.986). Mean SWV of the testicles with TML and normal testicles with control group was 1.18 +/- 0.22 cm/s and 0.88 +/- 0.11 cm/s, respectively. The SWV of the testicles with TML was higher than the normal testicles and this was statistically significant (P < 0.001). Conclusion: This study has shown that tissue stiffness in patients with TML is increased compared to the normal population. ARFI elastography helps the early detection of microstructural changes in TML and can be used for screening and follow-up.