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Öğe The effect of sinularia on spinal cord trauma(2020) Kaya, Ismail; Aydin, Hasan Emre; Kaya, Ismail; Ozen, Hulya; Kizmazoglu, Ceren; Atar, Murat; Uzunoglu, Inan; Yuceer, NurullahAim: Spinal cord traumas have become a serious health problem with the increase in the ageing population in society. The present study aimed to show the anti-inflammatory activity of methylprednisolone and sinularia administered following spinal cord trauma.Materials and Methods: Sea corals are widely found on earth. Sinularia is one of the 17 known active substances of sinularia flexibilis, and several studies have been conducted on its anti-inflammatory, anti-oedema and cytotoxic effects. Despite the recent scientific studies, discussions continue as there are no effective treatment methods in use apart from methylprednisolone; however, the test animals received methylprednisolone treatment to compareits effects with those of sinularia, a secondary active ingredient of s. flexibilis.Results: Paired comparisons for serum IL-1β and tissue TNF-α were made with Dunn's test. When serum IL-1β and tissue TNF-α levels were evaluated, a significant difference was detected in the group taking sinularia treatment compared to the trauma group Sinularia treatment was more efficient on different cytokines and compared to methylprednisolone treatment used routinely, it significantly affected both IL-1β level and TNF-α levels in serumConclusion: Anti-edematous, cytotoxic and anti-inflammatory effects of sinularia have been shown in our study. Sinularia, which has no known harmful effect on the human body according to the literature, may be clinically used in the future; however, more detailed and supportive experimental studies should be conducted on the subject.Öğe Effects of acute exercise on the diameter of the spermatic vein, and duration of reflux in patients with varicocele(Informa Healthcare, 2013) Atar, Murat; Soylemez, Haluk; Oguz, Fatih; Beytur, Alt; Altunoluk, Bulent; Kahraman, Bayram; Islamoglu, YahyaObjective. The aim of this study was to investigate the effects of acute exercise on the diameter of the spermatic vein, and on the duration of reflux in patients with varicocele. Material and methods. The study included 38 patients with complaints of infertility and scrotal pain between 2009 and 2010. The diagnoses were made by physical examination and colour Doppler ultrasound, with both performed before and after exercise tests. Results. The mean age of the participants was 25.7 +/- 4.9 years. During the first examination, the grades of the varicoceles detected were as follows: grade I, n = 7; II, n = 10; and III, n = 21. The diameters of veins in patients with grades I, II and III varicocele were 2.1 mm, 2.9 mm and 4.2 mm, respectively, before exercise, whereas they were 2.6 mm, 3.2 mm and 4.3 nun, respectively, after exercise. In patients with grade I varicoceles, compared with pre-exercise values, the diameter of the left spermatic vein and duration of reflux measured during Valsalva manoeuvres were increased significantly after exercise (p = 0.042 and p = 0.034, respectively); similar results were obtained for the patients with grade II varicoceles (p = 0.007 and p = 0.008, respectively). However, the minimal relative increase in cases with grade III varicoceles was not statistically significant (p > 0.05). Conclusions. This study demonstrates that acute exercise increases the spermatic vein diameter and reflux time in patients with varicoceles. These outcomes demonstrate that acute exercise may be an aggravating factor for varicocele, as seen in chronic exercise.Öğe Seven batteries in the bladder due to autoerotism(İnönü Üniversitesi Sağlık Bilimleri Dergisi, 2012) Söylemez, Haluk; Çakıcı, Hakan; Sancaktutar, Ahmet Ali; Atar, Murat; Bozkurt, YaşarRecently the frequency of foreign bodies in the urinary tract is increasing. Except the iatrogenic reasons, most foreign bodies in the lower genitourinary tract are self-inserted via the urethra as the result of exotic impulses, psychometric problems, sexual curiosity or sexual practice while intoxicated. Although the presentation of urinary foreign bodies has frequently been described in the medical literature, the insertion of foreign bodies through the urethra for reasons of sexual gratification has rarely been considered. A 23-yearold young girl admitted to emergency service complaining of macroscopic hematuria and pelvic pain for last 2 days. About 6-7 radioopaque density were observed on the plain X-ray and thought to be multiple batteries. Then she gave a history of insertion of many batteries into the urethra six days ago. Under spinal anesthesia a cystoscopic examination was performed. Seven batteries were observed in the bladder with hemorrhage and edema of the mucosa without any perforation and a pfannenstiel incision was made and batteries were removed successfully. Here we reported a case of self-inserted seven batteries in to the bladder due to autoerotism with a brief review of the literature.Öğe A understanding of the three dimensional microsurgical anatomical architecture of the temporal lobe with its functions(2021) Atar, Murat; Kizmazoglu, Ceren; Uzunoglu, Inan; Cingoz, Ilker; Gurkan, Gokhan; Kaya, Ismail; Sozer; Gulden; Ozdilmac, Ahmet; Yuceer, NurullahAim: This study aimed to evaluate the human brain temporal lobe white matter pathways with respect to microsurgical anatomy, reveal the relationship between these white matter pathways, evaluate their functions, which are already known in the literature, and contribute to the literature to establish safe temporal region surgical interventions. Material and Methods: 10 specimens of postmortem human brain hemispheres were fixed in accordance with Klingler’s method. Subsequently, dissection of the temporal lobe white matter pathways was performed under a surgical microscope. Each stage of dissection was achieved using the technique of merging multiple focus images in high-quality three-dimensional images. Results: The data obtained in lateral-to-medial and medial-to-lateral dissections were compatible with the literature. Moreover, microsurgical three-dimensional architectural structure of temporal lobe white matter pathways has been clearly revealed. The horizontal and vertical segments of superior longitudinal fasciculus were detected. The limbic system, connection of central cores with the temporal lobe, temporal stems region, and relationship with other fiber systems have been shown in this study. The importance of the temporal stem and Meyer’s loop for safe interventions on temporal lobe has been noted. Conclusion: Temporal region white matter pathways should be handled in a multimodal system, and anatomical knowledge of these white matter pathways should be mastered before performing temporal surgical interventions. Furthermore, the surgical strategy and preoperative planning should be discussed considering the relationship between the lesion and white matter pathways, thereby reducing neurosurgical morbidity and mortality.
