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Öğe Bismuth subcitrate nephrotoxicity - A reversible cause of acute oliguric renal failure(Karger, 2002) Sarikaya, M; Sevinc, A; Ulu, R; Ates, F; Ari, FBismuth subcitrate is a known nephrotoxic agent that may lead to acute oliguric renal failure when ingested in toxic doses. We report a 17-year-old girl who was admitted to the emergency room with complaints of nausea, vomiting, and anuria. She had taken 25 tablets containing 300 mg bismuth subcitrate (total 7.5 g). The patient was managed with hemodialysis started a week after ingestion. Bismuth subcitrate nephrotoxicity should be considered in the differential diagnosis of acute renal failure. Copyright (C) 2002 S. Karger AG, Basel.Öğe Clinical significance of pulmonary function tests in patients with acute pancreatitis(Springer, 2006) Ates, F; Hacievliyagil, S; Karincaoglu, MThe aim of the present study was to investigate changes in pulmonary function tests (PFTs) in patients with acute pancreatitis (AP), to compare them with those changes in healthy controls, and to analyze the relationship between these parameters and computed tomography severity index (CTSI) and Ranson's criteria scores as markers of disease severity. This study included 40 patients with AP without a diagnosis of any pulmonary disease and 40 sex- and age-matched healthy controls. All participants were evaluated with simple PFTs and single-breath carbon monoxide (CO) diffusion tests. Patients with AP were also evaluated according to their CTSI and Ranson's criteria scores as markers of disease severity. The forced vital capacity (FVC), forced expiratory volume in the first second (FEV1), FEV1/FVC, and peak expiratory flow, which determine lung capacity, were similar in the two groups. The forced expiratory volume during the middle half of the FVC (FEF25 - 75%), CO diffusing capacity (D-LCO), and ratio of D-LCO to alveolar ventilation (D-LCO/V-A), which determines alveolar membrane permeability, revealed a statistically significant decline in pulmonary gas exchange in patients with AP (P < 0.05). Correlation analysis showed that there is a significant negative relationship between CTSI and Ranson's criteria scores with FEF25 - 75%, D-LCO, and D-LCO/V-A (P < 0.05). We suggest that AP may cause impaired alveolar gas exchange without manifest pulmonary diseases. The effect of AP on FEF25 - 75%, D-LCO, and D-LCO/V-A appears to be dependent not only on the disease, but also on its severity. FEF25 - 75%, D-LCO, and D-LCO/V-A may give additional prognostic information in patients with AP in the initial evaluation.Öğe CRP and depression in patients on chronic dialysis(Dustri-Verlag Dr Karl Feistle, 2003) Taskapan, H; Ates, F; Kaya, B; Kaya, M; Emul, M; Taskapan, Ç; Sahin, I[Abstract Not Available]Öğe Interval analysis in patients with acute biliary pancreatitis(Lippincott Williams & Wilkins, 2005) Ates, F; Kosar, F; Aksoy, Y; Yildirim, B; Sahin, I; Hilmioglu, FBackground: It has been previously proposed that electrocardiographic abnormalities may be associated with acute pancreatitis. However, there is a lack of data on the QT interval and dispersion value in patients with acute pancreatitis, and no data are also available concerning QT interval and QT dispersion in acute biliary pancreatitis ( ABP). Aims: We aimed to investigate the QT parameters in patients with ABP, to compare them with those of healthy controls, and to analyze the relationship between QT parameters and Ranson score. Methods: The present study included 32 patients with acute biliary pancreatitis and 35 healthy controls. The severity of the pancreatitis was determined by Atlanta criteria: fewer than 3 Ranson criteria or fewer than 8 APACHE II ( the Acute Physiology and Chronic Health Evaluation) points indicated the mild disease ( group 1); 3 or more Ranson criteria or 8 or more APACHE II points or organ failure or systemic complications or local complications indicated the severe disease ( group 2). On admission, all patients underwent a standard 12-lead electrocardiogram, and corrected maximum QTc interval (QTc(max)), corrected minimum QT interval (QTc(min)), and corrected QTc dispersion (QTcd) values of the subjects were measured according to the Bazett formula in this study. Results: QTc(max) and QTcd were significantly longer in patients with ABP than in healthy controls ( 442 6 38 milliseconds versus 413 6 34 milliseconds, P< 0.05; and 67 +/- 21 milliseconds versus 42 +/- 18 milliseconds, P< 0.001, respectively). Similarly, QTc(max) and QTcd were significantly longer in group 2 than in group 1 ( 440 6 38 milliseconds versus 450 +/- 34 milliseconds, P< 0.01; and 66 +/- 9 milliseconds versus 71 +/- 11 milliseconds, P< 0.01, respectively). Correlation analysis showed that there is a significant positive relationship between Ranson scores of patients and QTcmax and QTcd ( P< 0.01 and P< 0.001, respectively). Conclusion: The effect of acute biliary pancreatitis on QT intervals and dispersion appears to be dependent not only on the disease but also on its severity, and these parameters may give additional prognostic information in ABP patients, even in the initial evaluation.Öğe Psychiatric disorders and large interdialytic weight gain in patients on chronic haemodialysis(Blackwell Publishing Asia, 2005) Taskapan, H; Ates, F; Kaya, B; Emul, M; Kaya, M; Taskapan, Ç; Sahin, IAims: Psychiatric disorders have been considered in terms of non-compliant behaviour and low life quality in haemodialysis patients. The aim of this study is to investigate the potential association of psychiatric disorders with compliance of fluid restriction and nutritional status and to measure the effects of psychiatric disorders on the life quality in chronic renal failure patients on haemodialysis. Methods: The study was conducted between April 2002 and December 2002 at a University hospital haemodialysis unit. The study population included 40 chronic renal failure patients (15 females/25 males). The Hamilton Depression Rating Scale ( HDRS), Hamilton Anxiety Rating Scale (HARS) and Primary Care Evaluation of Mental Disorders (PRIME-MD), The Mini Mental State Examination (MMSE) and Short Form Health Survey 36 (SF-36) were used for patient assessment by a trained psychiatrist. The subjects' medical charts were reviewed by a physician who was unaware of the the results of the psychiatric assesments. Interdialytic weight gain (IDWG %) and nutritional status were used as an index of diet compliance. Nutrition was assessed by using subjective global assessment ( SGA), serum albumin, predialysis phosphorus and potassium levels. Results: All patients' MMSE were normal. A diagnosis of a depressive or anxiety or somatoform disorder by the PRIME MD was made in 65% of the patients. Fourteen (35%) of the patients had a depressive disorder, 13 (32.5%) of the patients had a somatoform disorder, and 12 (30%) had an anxiety disorder. We found no relationship between any psychiatric disorder and age, sex, duration of dialysis therapy, education, marital status, employment, socioeconomic status, serum albumin, phosphorus, potassium or SGA (P > 0.05). In patients with depression or a somatoform disorder, the interdialytic weight (%) was significantly higher than those of the patients without these disorders (P < 0.05). All indices of quality of life decreased in patients diagnosed with a psychiatric disorder. Conclusion: Depressive symptoms are important determinants of patients' large interdialytic weight gain and psychiatric disorders that effect a patients' overall quality of life. Evaluation of psychiatric status should be part of the care provided to haemodialysis patients.
