Yazar "Atmaca R." seçeneğine göre listele
Listeleniyor 1 - 4 / 4
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Acute abdomen in a case with noncommunicating rudimentary horn and unicornuate uterus.(2005) Atmaca R.; Germen A.T.; Burak F.; Kafkasli A.Unicornuate uterus with a rudimentary horn is the rarest congenital anatomic anomaly of the female genital system, causing many obstetrical and gynecologic complications. The frequency of this pathology is approximately 1/100 000. A rudimentary horn usually develops following insufficient development of mullerian ducts. These patients present with dysmenorrhea, dyspareunia, and chronic pelvic pain because of endometriosis and rarely with acute abdominal symptoms following distention and torsion of the noncommunicating rudimentary horn. The case of a patient referred for acute abdomen after distention of a noncommunicating rudimentary horn is presented herein.Öğe Effect of etidronate on urinary Calcium/Creatinin ratio in postmenopausal women: A prospective, randomized, placebo controlled study(1999) Kucuk S.; Gokdeniz R.; Atmaca R.; Uryan I.; Buhur A.; Taskin O.There are both histomorphometric and nonhistomorphometric studies confirming that etidronate reduces bone resorption. In this study, we have examined urinary Calcium/Creatinine ratio (uCa/Cr) as a biochemical marker of bone turnover to show the effectiveness of etidronate and whether it could be used as a follow-up parameter of treatment. Eighty-one postmenopausal women aged 40 to 65 included into the study to investigate the effects of etidronate on uCa/Cr in a prospective, randomised, placebo controlled clinical trial. All necessary criteria matched 81 women were divided into 3 groups at random, each group consisted of 27 patients. Prior to treatment, uCa/Cr was calculated from all subjects 3 hours after drinking 1 liter of water in the morning. Twenty seven (33.3%) women were randomised to oral doses of etidronate (400 mg/day for two weeks followed by drug free period of 10 weeks), twenty seven women to etidronate (400 mg/day for two weeks) plus calcium (1000 mg/day) for the following 10 weeks and twenty seven women to placebo (Fe, 50 mg/day) for 12 weeks. After 12 weeks of treatment, uCa/Cr declined significantly in the etidronate group from 0.118±0.064 to 0.053±0.021, in etidronate+calcium group from 0.08±0.03 to 0.06±0.015 ((p=0.004) and (p=0.005), respectively). In the placebo group no significant change was observed (p=0.03). In conclusion, etidronate is effective in postmenopausal women and the effectiveness of treatment may be followed up by measuring uCa/Cr which is a simple and cheap parameter of determining the effectiveness of etidronate in prevention of osteoporosis. However, since there are contradictory findings concerning uCa/Cr exist, larger clinical and prospective studies should be carried out.Öğe Malon dialdehyde, nitrite and adrenomedullin levels in patients with premenstrual syndrome(2007) Balat O.; Dikensoy E.; Ugur M.G.; Atmaca R.; Cekmen M.; Yurekli M.Objective: To assess the levels of malon dialdehyde (MDA); a lipid peroxide product, total nitrite; a stabile product of nitric oxide (NO), and adrenomedulin (AM), to determine whether their levels are altered in premenstrual syndrome (PMS) and to search for their possible pathophysiological role in this peculiar syndrome. Study design: Twenty-one patients aged between 28 and 37 years, who had regular menses for at least six previous cycles, and were in general good health condition, were taken into the study. Blood samples were obtained from each patient at the 3rd and 21st day of their menstrual cycles. AM, nitrite, MDA and estradiol levels have been assessed in these samples for each patient. Results: No statistically significant difference in terms of age, parity and body mass index was detected among groups (P > 0.05). Nitric oxide levels were higher on the 3rd day, compared to 21st day in the study group, and this difference was statistically significant (P < 0.05). In the study group, 21st day AM levels were significantly higher when compared to the control group (P < 0.05). Conclusion: Even though various stress symptoms are present in PMS, there is no change in the levels of MDA, an oxidative distress indicator but AM and NO may have a pathophysiological role on this enigmatic disease. © 2006 Springer-Verlag.Öğe Results of 78 intrauterine insemination (IUI) cycles with husband sperm in infertility and factors affecting IUI success: A retrospective study(2005) Kiliç S.; Beytur A.; Altunoluk B.; Beytur L.; O?uz F.; Atmaca R.Introduction: Intrauterine insemination (IUI) with or without controlled ovarian hyperstimulation is a widely used therapeutic option for a variety of causes of infertility. Compared to in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI), IUI is efficient and more cost-effective than the others for the treatment of unexplained and nonsevere male factor infertility. In this retrospective study, we aimed to determine our IUI outcomes and the variables influencing IUI success. Materials and methods: To determine the influence of several parameters (age, duration and type of infertility, semen parameters, presence of varicocele, varicocelectomy and smoking histories) on the outcome of IUI in 35 women undergoing ovarian stimulation with clomiphen citrat, a retrospective review of 78 IUI cycles, which were done for the treatment of infertility using fresh husband sperm, was performed for approximately 1 year on data from the IUI program. Results of Pre-IUI evaluations were normal in all women and all men had normal semen analyses results. Discontinuous gradient centrifugation (DGC) with Sil-Select Plus was used for sperm preparation. Maximum number of IUI cycles per couple was three. In statistical analysis, ?2, Fisher's exact and Mann-Whitney U tests for in- and between-group comparisons and Pearson and Spearman tests for correlation analyses were used. Results: Primary and secondary infertility were determined in 25 and 10 couples, respectively. Fourteen men had varicocelectomy history. Ten men were smoking cigarette. Seven men had left varicocele at physical examination. Means of man and woman age and infertility duration were 29.94±4.72 (23-46) years, 27.46±4.55 (20-38) years and 63.23±30.88 (15-123) months, respectively. The pregnancy rate was 8.97% (7/78) per treatment cycle, 20% (7/35) per patient, 5.71% (2/35) for first cycle, 10.34% (3/29) for second cycle and 14.3% (2/14) for third cycle. All pregnancies were normal. No miscarriage, tubal pregnancy, birth defect and prematurity were observed. Difference between the pregnancy rates of each cycle was statistically insignificant (p=0.697). There were statistically significant negative correlations between the pregnancy rate and mean ages of the men and especially women (p=0.041, p=0.009, respectively). However, no correlation was found between pregnancy rate and infertility duration (p=0.108). DGC procedure increased percents of the sperms moving with a slow, meandering forward progression (grade 2) and in a straight line with high speed (grade 4) and decreased percent of sperms with no movement (grade 0) very significantly, without changing the percent of those with sluggish or nonprogressive movement (grade 1). However no-one of the pre and post-DGC semen analysis parameter was found to have influence on pregnancy rate. Pregnancy rates in the primary and secondary infertile couples were statistically indifferent. Pregnancy rates achieved in patients without varicocele or with a history of successful varicocelectomy were higher than those with untreated varicocele and with a history of unsuccessful varicocelectomy. There was not any statistically significant difference between the pregnancy rates in the patients with and without smoking history. Conclusion: The most significant predictors of success of IUI with fresh husband sperm in infertile couples were age of the woman and man. Absence of varicocele and treatment of it seemed to have affirmative effect on pregnancy rate.
