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    Association of neutrophil / lymphocyte ratio, platelet / lymphocyte ratio and brachial retinal vein occlusion
    (2019) Atum, Mahmut; Yuvaci, İsa; Yaylaci, Selcuk; Genc, Ahmed Bilal; Ucak, Turgay; Bozkurt, Erdinc; Alagoz, Gursoy
    Aim: In this study, we aimed to measure neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) levels in brachial retinal vein occlusion (BRVO) patients and to determine whether there it could be used as a marker for BRVO. Brachial retinal vein occlusion is a serious disease that causes vision loss and is associated with inflammation.Material and Methods:This retrospective study included 77 patients with BRVO and 69 healthy controls. BRVO was diagnosed with ophthalmic examination. Blood samples were obtained from venous blood and serum neutrophil, lymphocyte, and platelet data of all patients were recorded also, NLR-PLR values were calculated. Results:Significant difference were not found between the BRVO group and control group with the level of white blood cells (WBC) and platelets (p>0.05). Neutrophil count was significantly increased in BRVOs compared to the controls (4.79±1.89 vs 4.02±1.47, p=0.007). Lymphocyte count was significantly decreased in BRVOs compared to the controls. (2.17±0.76 vs 2.52±1.03, p=0.022) NLR was significantly increased in BRVOs compared to the controls. (2.60±2.05 vs 1.74±0.70, p=0.001) Also, PLR was significantly increased in BRVOs compared to the controls. (129.70±68.77 vs 107.96±40.65, p=0.023)Conclusion: In our study we found that NLR and PLR were significantly increased in BRVOs than in controls.
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    Comparison of anterior segment parameters and corneal endothelial changes in patients with pseudoexfoliative glaucoma and pseudoexfoliation syndrome
    (2019) Ucak, Turgay; Atum, Mahmut; Karakurt, Yucel; Icel, Erel; Tasli, Nurdan Gamze
    Aim: The aim of this study is to evaluate the changes in anterior chamber morphology and corneal endothelium in patients with pseudoexfoliation syndrome (PEX) and pseudoexfoliative glaucoma (PEXG) and to determine the differences according to the control group. Material and Methods: 61 eyes of 61 PEX patients, 56 eyes of 56 PEXG patients and 46 eyes of 46 healthy subjects were included in the study. Measurement of intraocular pressure (IOP) was taken and axial length (AL), K1, K2, central corneal thickness (CCT), white-to-white distance (WTW), anterior chamber depth (ACD), pupil diameter (PD) by optical biometry and endothelial cell density (ECD), polimegatism (CV), pleomorphism (HEX) and average cell area (AVG) by specular microscope were taken of all the patients. Evaluation among the groups were made by ANOVA test, and p <0.05 was considered significant. Results: The mean age of PEX, PEXG and control group were 63.79 ± 6.62; 62.71 ± 10.73; 63.43 ± 10.58 years respectively (p> 0.05). There were no statistically significant differences among the groups in terms of IOP, AL, K1, K2, WTW, ACD (p> 0.05). Pupil diameter values were lower in the PEX group. CCT and endothelial cell counts were found to be higher in the control group compared to the other groups, while no significant difference was found between PEX and PEXG groups. AVG results were found to be significantly higher in the PEXG group than in the control group (p <0.05). No difference was observed among the groups when CV and HEX values were examined. Conclusion: In our study, no significant difference was observed among the groups in terms of the IOP, AL, K1, K2, WTW, ACD, while corneal thickness and endothelial cell density were observed to be lower in PEX and PEXG groups compared to the healthy individuals.
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    A cost minimization analysis of intracameral cefuroxime and moxifloxacin in cataract surgery
    (2019) Atum, Mahmut; Dogan, Emine; Ucak, Turgay; Bozkurt, Erdinc; Cucen, Bulent; Celik, Erkan; Yuvaci, Isa
    Aim: In this study, we aim to perform Cost Minimization Analysis of cefuroxime and moxifloxacin, which have proven to have a similar efficacy in the prophylaxis of endophthalmitis after cataract surgery.Material and Methods: The records of 1097 patients who had undergone cataract surgery and intracameral antibiotic (cefuroxime, moxifloxacin) injection in 2018 were evaluated retrospectively. Patients undergoing cataract surgery were divided into two groups according to the type of antibiotic injected into the anterior chamber. Group 1 consisted of patients who received intracameral 1mg/0.1ml cefuroxime and Group 2 consisted of patients who received intracameral 500 µg /0.1ml moxifloxacin. In the postoperative period, patients in both groups received topical antibiotic drops containing 0.5% moxifloxacin and steroid drops containing 0.1% dexamethasone for 7 days. Results: The Group 1 consisted of 213 (19.4%) patients, of which 97 (45.5%) were male and 116 (54.5%) were female, while Group 2 consisted of 884 (80.6) patients, of which 439 (49.7%) were male, and 445 (50.3%) were female (p=0.280). The groups were similar in terms of age and gender distribution of the patients. There was no significant difference in terms of the posterior capsule rupture development between the two groups (p=0.692).BCVA was statistically significant before and after surgery in both groups. None of the patients in both groups developed endophthalmitis. The cost of the drugs used in the first group was 3 times higher than the second group.Conclusion: The antibiotics injected to the anterior chamber during cataract surgery have similar effectiveness, moxifloxacin injection to the anterior chamber was found to be more advantageous in terms of cost, compared to the use of disposable cefuroxime.Keywords: Cataract surgery; intracameral antibiotic; cost.