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    Evaluation of IL-32 Levels in Gingival Tissue and Serum of Experimental Periodontitis Model
    (2017) Ongoz Dede, Figen; Balli, Umut; Durmuslar, Mustafa Cenk; Bozkurt Dogan, Seyma; Avci, Bahattin; Ayas, Bulent; Tuncel, Ozgur Korhan
    Aim: Interleukin (IL)-32, a recently discovered proinflammatory cytokine, is demonstrated in several infectious diseases. The goal of this study is to investigate the levels of IL-6, IL-10 and IL-32 in gingival tissue and serum of rats with experimental periodontitis.
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    Relationship between gingival inflammation and total glutathione
    (2017) Ongoz Dede, Figen; Bozkurt Dogan, Seyma; Balli, Umut; Avci, Bahattin
    Aim: Glutathione, which is known to be the main antioxidant, is the foremost redox regulator in the control of inflammatory processes. The goal of this study was to investigate the levels of total glutathione, which plays a central role in cellular antioxidant defense, in the gingival crevicular fluid (GCF) and plasma of individuals with gingivitis and periodontally healthy.
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    Serum amyloid-a may be an early marker in diagnosis of preterm premature rupture of membrane and chorioamnionitis
    (2019) Kayabas, Hatice; Devran Bildircin, Fatma; Karli, Pervin; Avci, Bahattin; Alper, Tayfun; Ozdemir, Ayse Zehra
    Aim: To determine the efficiency of serum amyloid-A (SAA) in predicting preterm premature rupture of membrane (PPROM) and chorioamnionitis in risky cases. Study Design: The study consists of 20 women 26-37 weeks of pregnancy who had PPROM and 20 pregnant women without water breaks. Levels of SAA were determined in maternal venous and umbilical cord blood. Results: SAA values in cord blood and venous blood of mothers with PPROM were higher than in the control group (p0,05). SAA values in the patients with clinical chorioamnionitis (n=9) were significantly higher (p0,05) than both PPROM patients without chorioamnionitis (n=11) and the control group (n=20). Conclusion: In women at risk for PPROM in whom diagnosis cannot be established, blood SSA levels can be used as a marker. Increased SAA values in pregnant women with PPROM who were conservatively treated were considered a marker for chorioamnionitis.