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    Annular lichen planus of the eyelid: A rare entity
    (2020) Ayhan, Erhan; Bulut, Ecem; Akman, Zehra; Dere, Gokturk; Onder, Sevda
    Lichen planus (LP) is a common inflammatory dermatosis. Annular LP affecting the only eyelid, however, has rarely been reported. Diagnosis of annular LP limited to the eyelid can be a real challenge. We report a case of annular LP limited to the eyelid with its clinical, dermoscopic and histopathological findings.
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    Clinical features of patients diagnosed with recidivan cutaneous leishmaniasis
    (2020) An, Isa; Ozturk, Murat; Aksoy, Mustafa; Yentur, Nebiye; Ayhan, Erhan; Eroglu, Naime
    Aim: Cutaneous leishmaniasis (CL) is a disease with chronic nodulo-ulcerative lesions on the skin that heals with atrophic scars. This study aims to investigate the clinical features of patients admitted to our clinic and diagnosed as recidivan CL.Material and Methods: This retrospective study included 11 patients who were admitted to our skin and venereal diseases clinic between October 2017 and July 2019 and who were diagnosed as recidivan CL by anamnesis, clinical and microscopic examination. Clinical characteristics of the patients such as age, sex, survival in the endemic region, intralesional or systemic antimony therapy and number, location, size and duration of the lesions were recorded.Results: Seven (63.6%) of the 11 patients were male and 4 (36.4%) were female. The mean age of the patients was 13.8 ± 4.04 years. All of the patients in the study had one lesion on their face. The mean lesion duration was 36.27 ± 24.3 months. The mean lesion size was 6.9 ± 3.4 cm. Before the diagnosis, 2 (18.2%) patients received intralesional antimony treatment, 1 patient (9.1%) received systemic antimony treatment, and 8 (72.7%) patients did not receive any treatment.Conclusion: In conclusion, recidivan CL is a rare form of chronic CL. Because parasites are rare in the lesions, the diagnosis is usually delayed and therefore the lesions can cause destruction and deformity. Prospective studies with a large number of patients are needed to better understand the clinical findings of recidivan CL.
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    The effect of isotretinoin on depression and anxiety in patients with acne vulgaris: A prospective study
    (2019) Ayhan, Erhan; Donmezdil, Suleyman
    Aim: The aim of this study was to evaluate the effect of isotretinoin on depression and anxiety.Material and Methods: Beck depression and Beck anxiety scales were performed by the clinician before the initiation of isotretinoin therapy. At follow-up, 0.5 mg/kg/day isotretinoin was administered to the patients. In the third month of the treatment, 39 patients were reevaluated with the same scales.Results: There was no statistically significant difference in pre-treatment (11.38±12.48) vs. post-treatment (10.48±9.77) change in Beck anxiety scale points. Similarly, although there was a decrease in the Beck depression scale scores in the pre-treatment (10.05±9.02) and post-treatment (8.74±9.45) scores, no significant difference was found. Although the decrease in scores was not statistically significant, the decrease in both depression and anxiety scores after treatment showed a statistically significant correlation in itself (p0.01).Conclusions: As a result, in this study, we determined that isotretinoin treatment does not reveal any psychiatric symptoms and the current anxiety decreases depressive symptoms. For more clear findings, screening of the side effect profile with extensive and multicentre studies will contribute to the literature.Keywords: Isotretinoin; depression; anxiety; acne vulgaris.
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    Is diabetic dermopathy related with microangiopathic complications?
    (2019) Ayhan, Erhan; Arac, Esref
    Aim: Diabetic dermopathy is a skin disease, seen in patients with diabetes mellitus, characterized by atrophic scar and hyper-pigmented lesions. Recently, it was proposed that this disease might be associated with other microangiopathic complications of diabetes such as retinopathy, nephropathy, and polyneuropathy. In this study, patients with diabetic dermopathy were compared with two control groups to test the validity of these associations.Material and Methods: Twenty-three patients, who admitted to Dermatology Outpatient Clinic Health Sciences University Gazi Yaşargil Education and Research Hospital and diagnosed as diabetic dermopathy were included in the study. Twenty-three patients with well controlled diabetes mellitus (Control Group A) who treated as outpatients and 23 patients with diabetes mellitus who had poor general status and hospitalized by internal medicine department (Control Group B) were included as two control groups. Patients were evaluated in terms of retinopathy, nephropathy, neuropathy, heart attack history and diabetic foot ulcer.Results: In the study 82.6% (n:19) of patients were male and 17.4% (n:4) were female (female: male ratio 4.75:1). There was no significant relationship between fasting blood glucose and HbA1c elevation with retinopathy, neuropathy, polyneuropathy and diabetic foot. However, there was a significant relationship between fasting blood glucose levels and heart attack. Although heart attack history and diabetic foot was more common in the patient group and retinopathy, nephropathy and polyneuropathy was more frequent in the Control Group B, there was no significant difference between both groups.Conclusions: In conclusion, microangiopathic complications, heart attack and diabetic foot are not only common in the patient group with diabetic dermopathy but also in the Control Group B. Even though these complications were more common in these two groups, there was no significant difference between each and the other diabetic (Control Group A).Keywords: Diabetes mellitus; diabetic dermopathy; skin lesions; cutaneous manifestations.