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    Determination of bone age using deep convolutional neural networks
    (2021) Senel, Fatih Ahmet; Dursun, Ahmet; Ozturk, Kenan; Ayyildiz, Veysel Atilla
    Aim: Bone age assessment is an important measure of skeletal maturity in children with a growth development disorder. Furthermore, age estimation is an important method applied in various situations such as growth observation, immigrant registration, legal criminal justice, and body detection. In this study, we aimed to develop a computer-assisted bone age detection system. Materials and Methods: This detection is usually evaluated by a trained physician using a radiological examination of the left wrist and a reference model. However, this evaluation method was stated to cause differences brought by interobserver and intraobserver variabilities. Several automated approaches have been proposed to overcome these problems, but none of them have been proven to be generalized according to different races, age ranges, and gender. Considering today's technology, it is observed that developments in the software are already used in the field of health. In this study, bone age was determined from X-rays of the left wrist using convolutional neural networks, which are a popular subject of recent years. Results: In the study, in which a total of 150 patients' images were used, different deep learning architectures were used and the results were compared. On average, the success rate was best at 98.39% with different training-testing split rates. Conclusion: This study demonstrated that deep learning could be used to determine bone age.
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    Evaluation of hard palate asymmetry in turkish population
    (2021) Ayyildiz, Veysel Atilla; Dursun, Ahmet
    Aim: In a sample of the Turkish population, we aimed to evaluate differences in hard palate asymmetry by sex, the direction of right-left dominance, and how hard palate asymmetry and morphometric measurements are shaped with age.Materials and Methods: The present study was conducted on 3-dimensional computed tomography images of the head and neck region belonging to 172 (88 males, 84 females) individuals aged between 20-89 years. In this study, the distances between the Incisive foramen-Greater palatine foramen, Greater palatine foramen-Posterior nasal spine on the right and left sides with regard to the hard palate were measured. The asymmetry ratio was determined as a percentage using the asymmetry index. Furthermore, the angle values between the Incisive foramen-Posterior nasal spine-Greater palatine foramen on the right and left sides were measured on the lines between the measured points and compared with each other.Results: The measured parameters were compared between sexes, higher linear measurement parameters were found in males; angular values and the asymmetry index were close to each other, and no difference was found between them. When a comparison was made between the sides, the difference was revealed only in the measurement of the Greater palatine foramen-Posterior nasal spine, and the right side was larger. In all cases, the right side was larger in 79 cases in the Incisive foramen-Greater palatine foramen asymmetry index, and in 93 cases, the asymmetry was to the left. In the Greater palatine foramen-Posterior nasal spine asymmetry index, it was found that the asymmetry was to the right in 61 cases, and the asymmetry was to the left in 111 cases. Conclusion: This study provided important data on the hard palate morphology of the Turkish population. It also presented anthropological references for hard palate measurements of the Turkish population. Using 3-dimensional computed tomography images, we determined the greater palatine foramen's location according to the posterior nasal spine and incisive foramen. Determining the greater palatine foramen's location according to anatomical structures will contribute to determining the location of the greater palatine foramen in surgical interventions to be performed in this region.
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    Vacuum-assisted breast biopsy of microcalcifications on the stereotactic prone table and comparison of the histopathologic diagnosis with mammographic features
    (2021) Ayyildiz, Veysel Atilla; Taydas, Onur; Basaran Demirkazik, Figen; Akpinar, Meltem Gulsun
    Aim: Breast cancer is one of the most important causes of mortality and morbidity in women. With the widespread use of screening mammography, the detection of non-palpable suspected cancerous lesions is increasing. Therefore, the use of vacuum-assisted breast biopsy in the management of breast lesions continues to increase. The aim of this study was to evaluate the histopathological results of suspicious microcalcifications which were diagnosed by vacuum-assisted needle biopsy on a stereotactic prone table and to compare the mammographic features of the microcalcifications with the histopathological results. Materials and Methods: The study included a total of 119 patients with a median age of 51 years (range, 33-77 years) who underwent stereotactic biopsy on a prone table because of suspicious microcalcifications between March 2010 and July 2014. Retrospective evaluation was made of the preoperative mammographic features, and the BI-RADS (Breast imaging-reporting and data system) scores of the microcalcifications and the vacuum biopsy and / or excisional histopathological results. Results: Stereotactic vacuum-assisted breast biopsy revealed that 52.1% of the lesions were benign and 47.9% were malignant. After vacuum-assisted stereotactic biopsy 61 patients underwent surgery. In 10 of these (16.3%) the final excisional histopathological diagnosis was benign, and in 51 (83.7%) malignancy was determined. Conclusion: Vacuum-assisted breast biopsy on a stereotactic prone table is a successful technique with a low failure rate for microcalcifications that are non-palpable and have no ultrasonographic findings.