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  • Küçük Resim
    Öğe
    Correlation between histopathological results and BI-RADS classification in breast masses
    (2019) Kutluer, Nizamettin; Aksu, Ali; Bozan, Mehmet Bugra; Kanat, Burhan Hakan; Kargici, Hulagu; Cay, Ferhat; Azak Bozan, Ayse
    Aim: The aim of this study was to determine the reliability of BI-RADS Classification by evaluating the correlation between BI-RADS Classification System and pathology results of patients admitted to the general surgery outpatient clinic of our hospital with the complaints of breast lump, breast pain and nipple discharge.Material and Methods: This retrospective study was conducted between 2009 and 2011. The study included a total of 150 female patients, who applied to the Research and Training Hospital General Surgery Polyclinics with the complaints of breast lump, pain and discharge which were classified as BIRADS-3, BIRADS-4 (4a, 4b, 4c) subcategories and BIRADS-5 category, and were evaluated using the epicrisis forms, test results (radiological imaging and tumor markers) and pathology reports.Results: The study included a total of 150 patients; 21 of which were classified as BI-RADS 3, 44 as BI-RADS 4a, 35 as BI-RADS 4b, 22 as BI-RADS 4c and 28 as BI-RADS 5. Of the masses determined to be benign, 21 cases (100%) were classified as BI-RADS 3, 43 cases (97.72%) as BI-RADS 4a, 34 cases (97.14%) as BI-RADS 4b, 8 cases (36.36%) as BI-RADS 4 and 1 case as BI-RADS 5 (3.57%). Of the malignant masses, 1 case (2.28%) was classified as BI-RADS 4a, 1 (2.86%) as BI-RADS 4b, 14 cases (63.64%) as BI-RADS 4c and 27 cases (96.43%) as BI-RADS 5.Conclusion: In the light of these data, we believe that the division of BI-RADS category 4 into sub-categories play an important role in management of breast masses.
  • Küçük Resim
    Öğe
    The diagnostic efficacy of some ischemic markers (urotensin II and urotensin II related peptide) in early diagnosis of intestinal ischemia in experimentally increased intraabdominal pressure in rats
    (2019) Bozan, Mehmet Bugra; Ayten, Refik; Bulbuller, Nurullah; Camci, Cemalettin; Aygen, Erhan; İlhan, Necip; Ozercan, Hanfi Ibrahim; Azak Bozan, Ayse; Aksu, Ali; Kutluer, Nizamettin
    Aim: The purpose of this experimental study is evaluating the relation between plasma urotensin-II (U-II) and urotensin-II related peptide (URP) levels with intestinal ischemia caused by elevated intraabdominal pressure.Material-Methods: Wistar albino rats weighing 200–250 grams used.Group-1: Laparatomized group without abdominal pressure elevation in sixty minutes under general anesthesia.Group-2: Ten mmHg elevated intraabdominal pressure group in sixty minutes under general anesthesia.Group-3: Fifteen mmHg elevated intraabdominal pressure group in sixty minutes under general anesthesia.Group-4: Twenty mmHg elevated intraabdominal pressure group in sixty minutes under general anesthesia.After sacrifing, in general anesthesia blood and tissue samples were collected. Hematoxilen and eosyn stained tissue samples were examined under light microscope.Results: Plasma U-II levels changes insignificant in group 2 and 3 but in group-4 was changed significantly compared with the control group(respectevely p=0,609; p=0.848; p=0.04). Plasma URP levels changed significantly in all groups compared with the control group (p-values were p=0.018; p=0.018 and p=0.04 respectively).Conclusion: U-II levels could not be a useful parameter for the early diagnosis of the intestinal ischemic damage caused byintraabdominal pressure(IAP), because it is found in all vascular structures. On the other hand, plasma URP levels would be used for the early diagnosis of the intestinal ischemia. Because of the limitations of our study, we believe that our results should be confirmed with clinical studies.Keywords: Intrabdominal hypertension; intestinal ischemia; urotensin-ii; urotensin-ii related peptid; abdominal compartment syndrome.