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    A case of syncopal convulsions triggered by glossopharyngeal neuralgia
    (Kare Publ, 2021) Tasci, Irem; Beydilli, Ibrahim; Demir, Caner Feyzi; Balgetir, Ferhat; Gonen, Murat; Bakir, Meryem
    Syncopal convulsions and epileptic seizures are clinically hard to distinguish and differ in terms of treatment approaches. It is important to consider the cardiac arrhythmias that impair cerebral perfusion in the differential diagnosis of antiepileptic treatment-resistant convulsions. Here, we offer a 72-year-old male patient glossopharyngeal neuralgia (GN) after swallowing associated with recurrent episodes of syncopal convulsions. The patient was successfully treated with temporary pacemaker and carbamazepine. This phenomenon is noteworthy in terms of both asystole triggered by GN and syncopal convulsions which are rare in the differential diagnosis of epileptic seizures.
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    The Efficacy of Lamotrigine and Levetiracetam Therapy on Serum Lipid Profile in Epilepsy Patients
    (Kare Publ, 2011) Kamisli, Ozden; Kaplan, Yuksel; Kamisli, Suat; Bakir, Meryem; Ozcan, Cemal
    Objectives: We aimed to investigate the efficacy of two new generation antiepileptics, lamotrigine (LTG) and levetiracetam (LEV), on serum lipid levels, since they are reported to be as effective as classical antiepileptics but with fewer side effects. Methods: We analyzed the files of all epileptic patients who were registered at Inonu University Faculty of Medicine, Turgut Ozal Medical Center, Neurology Department between April 2009 - May 2011 retrospectively. Patients treated with LTG and LEV monotherapy were found and total cholesterol (TC), triglyceride, low-density lipoprotein (LDL), very low-density lipoprotein (VLDL) and high-density lipoprotein (HDL) were measured. The patients' data were compared with a control group. Results: Twenty-one patients treated with LTG and 20 patients treated with LEV were included in this study. TC, triglycerides, LDL, VLDL, and HDL values were compared with 21 healthy control subjects. TC, triglycerides, LDL, VLDL, and HDL values showed no statistically significant differences between groups. Conclusion: Neither LEV nor LTG, which are new generation antiepileptics, affected blood lipid levels. We consider that they are safe to use in patients, especially those with atherosclerosis risk.
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    The Evaluation of Premenstrual Dysphoric Disorder Incidence and it's Relationship with Antiepileptic Drugs in Epilepsy Patients
    (Kare Publ, 2013) Kamisli, Ozden; Kamisli, Suat; Kartalci, Sukru; Bakir, Meryem; Kaplan, Yuksel; Ozcan, Cemal
    Objectives: Premenstrual dysphoric disorder (PMDD) is a condition characterized by psychiatric and somatic symptoms commonly seen in women of childbearing age. There are few studies investigating the prevalence of PMDD in patients with epilepsy. In this study we investigate the frequency of PMDD in epilepsy patients and evaluate the relationship between antiepileptic drugs and PMDD. Methods: The subjects were 93 women with epilepsy and 30 controls. Patients were divided into five subgroups according to their medications as carbamazepine, oxcarbazepine, valproic acide, lamotrigine, and levetiracetam. Each group were examined for the frequency of PMDD. In addition, the incidence of PMDD was compared according to antiepileptic drugs in subgroups. Results: The frequency of PMDD was similar in patients with and without epilepsy. Focal epilepsy group, especially temporal lobe epilepsy, has a higher incidence of PMDD, but similar results were also found in women without epilepsy. Looking at the relationship between antiepileptic treatments and PMDD, patients treated with lamotrigine had the lowest frequency. Conclusion: The frequency of PMDD was similar in patients with and without epilepsy. Focal epilepsy patients, especially temporal lobe epilepsy patients, had a higher incidence of PMDD. The LTG group had the lowest rate of PMDD. In terms of PMDD, LTG may be beneficial for young women with epilepsy.