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Öğe A Case of Anaphylaxis to Legumes During Prick to Prick Test(Bilimsel Tip Yayinevi, 2016) Yilmaz, Ozlem; Atici, Serkan; Ertoy Karagol, Hacer Ilbilge; Topal, Erdem; Bakirtas, Arzu; Demirsoy, Mehmet Sadik; Turktas, IpekThe most common causes of food allergy vary among countries according to the dietary habits and the frequency of consumption of foods. Legumes are important sources of protein that are widely consumed all over the world. The legume family includes lentils, chickpeas, beans, broad beans as well as peanuts and soybeans. Skin prick tests are generally considered safe. However, systemic reactions may develop during skin prick testing, Systemic reactions from skin testing are more frequent with food, drug, latex and venom allergens. Systemic reactions occur more frequently after prick to prick tests that are performed with fresh food than those with standard extracts. This paper reports a case with a history of anaphylaxis to lentils and peas. The patient was found to have type 1 reaction to chick peas, broad beans and green beans although she did not describe a reaction to these legumes in her history. The patient experienced anaphylaxis during skin testing with legumes when multiple tests were performed at the same time. There was no reaction when skin prick tests were performed in more than one session. The patient is noteworthy in this regard and discussed in detail.Öğe Four child cases diagnosed with DRESS syndrome(Bilimsel Tip Yayinevi, 2015) Karagol, Hacer Ilbilge Ertoy; Yilmaz, Ozlem; Topal, Erdem; Bakirtas, ArzuDrug Reaction with Eosinophilia and Systemic Symptoms'' (DRESS) syndrome, is characterized with fewer, extensive mucocutaneous rash, facial oedema, lymphadenopathy, eosinophilia and/or other hematological abnormalities and internal organ involvement that typically emerge following the latent period that varies between 2-6 weeks after the beginning of drug treatment. It is known that this syndrome, which is assessed among severe cutaneous adverse drug reactions, is less common in children than adults. Although many defining adult studies about DRESS syndrome exist, a limited number of studies in which child cases have been evaluated are available. Therefore, we offered four child cases that first of which is correlated with sulfonamide derivate use of antibiotics and the others of which are diagnosed with use of anticonvulsant dependent DRESS syndrome in our clinic. We aimed to discuss DRESS syndrome in children with clinical and laboratory characteristics, diagnosis and treatment of those cases whose ages vary between 7 and 14 years old.Öğe Healthcare workers' knowledge level regarding anaphylaxis and usage of epinephrine auto-injectors(Turkish J Pediatrics, 2021) Arga, Mustafa; Topal, Erdem; Yilmaz, Sila; Erdemli, Pinar Canizci; Bicakci, Kubra; Bakirtas, ArzuBackground. Inadequate practices in diagnosis and management of anaphylaxis in parallel with an increase in its prevalence may cause serious public health problems today. This is the first study aiming to assess the theoretical knowledge of professional and non-professional healthcare workers from different lines of the healthcare service chain about anaphylaxis management, and their practice approaches for epinephrine autoinjectors (EAIs) together. Methods. The study included 697 participants comprising physicians, dentists, pharmacists, and school staff. In face-to-face interviews, each participant was asked to fill out the questionnaire forms prepared for assessing their demographic characteristics, experience with a case of anaphylaxis and EAI and theoretical knowledge about the diagnosis and treatment of anaphylaxis, and to demonstrate how to use EAI in practice with trainer device. Results. The rates of 391 physicians, 98 dentists, 102 pharmacists and 105 school staff of knowing the diagnosis criteria of anaphylaxis were 47.6%, 31.6%, 31.1%, 19%, and knowing the first and life-saving treatment of anaphylaxis were 87.2%, 79.6%, 47.6%,15.2%, respectively. Predictors that affected physicians in knowing the first and life-saving treatment of anaphylaxis were having experience with EAIs [OR:5.5, (%95a1.330-23.351, p=0.015)1 and a case of anaphylaxis [OR:2.4, (%95CI:1.442-4.020, p=0.001)1, and knowing the administration route of epinephrine correctly [OR:1.9, (%95CI:1.191-3.314, 1,1008)]. 31.1% of the participants demonstrated the EAI usage correctly. The EAI usage steps with the most errors were Place the appropriate injection tip into outer thigh/Press the trigger so it 'clicks' and Turn the trigger to arrow direction (60.3% and 34.9%, respectively). Conclusions. Healthcare workers' knowledge level regarding anaphylaxis management and ability to use EAIs correctly are not adequate. That most errors were made in the same steps of EAI usage indicates that the industry should continue to strive for developing the ideal life-saving device.Öğe Pityriasis Likenoides et Varilioformis Acuta (PLEVA) prediagnosed as mastoscytosis(Bilimsel Tip Yayinevi, 2014) Ertoy Karagol, H. Ilbilge; Yilmaz, Ozlem; Gonul, Ipek Isik; Topal, Erdem; Bakirtas, ArzuWe presented 6 years-old boy who admitted to our clinic with a pre-diagnosis of cutaneous mastocytosis. The child had red-brown colored, diffuse maculopapular eruptions which were more pronounced on his trunk without any pruritus. The other findings on physical examination were normal. We performed punch biopsy from lesions on his skin to reveal the diagnosis. Histopathological examination of biopsy material was consistent with Pityriasis Likenoides et Varilioformis Acuta (PLEVA). He resolved without treatment in the follow-up period. In this report, we examined the clinical symptoms, diagnostic work-up and treatment of PLEVA and discussed the differential diagnosis of PLEVA with mastocytosis.