Yazar "Balli, Umut" seçeneğine göre listele
Listeleniyor 1 - 4 / 4
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Circulation levels of YKL-40 and Hs-CRP in stage 3 Molar-incisor pattern of periodontitis(2020) Balli, Umut; Keles Yucel, Zeynep PinarAim: To evaluate the novel acute phase protein YKL-40 and high-sensitive C-reactive protein (Hs-CRP) in serum of patients with molar-incisor pattern of periodontitis (Stage 3, Grade C).Material and Methods: Twenty seven patients with molar-incisor pattern of periodontitis and 27 periodontally healthy individuals were included into the study. Serum levels of YKL-40 and Hs-CRP were measured by enzyme-linked immunosorbent assay.Results: Serum YKL-40 levels were significantly increased in molar-incisor pattern of periodontitis patients compared to healthy controls (P0.05). Similarly, significantly higher serum Hs-CRP levels were found in the patients with molar-incisor pattern of periodontitis than those of healthy ones (P0.05). There were positive correlations between serum YKL-40 and Hs-CRP and BOP in healthy control group (P0.05 for all). Moreover, serum YKL-40 showed positively strong relationships with Hs-CRP and also clinical periodontal parameters (CAL and BOP) in the periodontitis group (P0.001 for all).Conclusion: The present data suggest that YKL-40 might be a candidate biomarker for the diagnosis of localized to molar-incisor pattern of periodontitis and may also have the potential to predict the future risk of systemic diseases for this distinct form of periodontitis.Öğe Evaluation of IL-32 Levels in Gingival Tissue and Serum of Experimental Periodontitis Model(2017) Ongoz Dede, Figen; Balli, Umut; Durmuslar, Mustafa Cenk; Bozkurt Dogan, Seyma; Avci, Bahattin; Ayas, Bulent; Tuncel, Ozgur KorhanAim: Interleukin (IL)-32, a recently discovered proinflammatory cytokine, is demonstrated in several infectious diseases. The goal of this study is to investigate the levels of IL-6, IL-10 and IL-32 in gingival tissue and serum of rats with experimental periodontitis.Öğe Investigation of oxidative stress in experimental periodontitis treated with myricetin(2020) Gulsoy, Zehra; Keles Yucel, Zeynep Pinar; Guven, Berrak; Balli, UmutAim: The aim of this study was to investigate the effects of systemically applied myricetin on oxidative stress and antioxidant status in experimental periodontitis of rats.Materials and Methods: 24 Wistar rats were used and randomly divided into three groups. Experimental periodontitis was induced by placing a silk ligature around first molars teeth of the rats for 15 days. Following removal of the ligatures, Group 1: saline; Group 2: myricetin and Group 3: doxycycline were administered systemically. Total antioxidant status (TAS), total oxidant status (TOS), oxidative stress index (OSI), superoxide dismutase (SOD) enzyme and malondialdehyde (MDA) levels in serum; and SOD and MDA levels in gingival tissue were determined by biochemical analysis.Results: Serum TAS increased and serum TOS and OSI values decreased in myricetin and doxycycline treated groups compared to saline group (P0.016). Gingival tissue SOD activity was increased in the group treated with doxycycline compared with the group treated with saline (P0.016). MDA levels in both serum and gingival tissue samples were decreased in myricetin and doxycycline treated groups compared to saline group (P0.016).Conclusion: The systemic administration of myricetin may be useful to diminish oxidative damage in periodontitis.Öğe Relationship between gingival inflammation and total glutathione(2017) Ongoz Dede, Figen; Bozkurt Dogan, Seyma; Balli, Umut; Avci, BahattinAim: Glutathione, which is known to be the main antioxidant, is the foremost redox regulator in the control of inflammatory processes. The goal of this study was to investigate the levels of total glutathione, which plays a central role in cellular antioxidant defense, in the gingival crevicular fluid (GCF) and plasma of individuals with gingivitis and periodontally healthy.
