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    ANTIMICROBIAL POTENTIAL OF SILVER NANOPARTICLES PRODUCED BY APRICOT LEAF EXTRACT
    (2022) Baran, Ayşe; Yeşilada, Özfer
    Metallic nanoparticles are important substances in medicine. These particles could be prepared by various ways including green synthesis. The production of silver nanoparticles by plant extracts is widely used because of their environmentally friendly properties. In this study, silver nanoparticles have been synthesized by biological method and Apricot tree (Prunus armeniaca) leaf extract was used as reducing agent. The color change and formation of the characteristic absorption peak at 400-500 nm were the first indications of AgNP formation. XRD analysis showed the crystalline particles and obtained AgNPs were generally in spherical shape with the average particle size of 24 nm. Their antimicrobial activity studies against various pathogenic microorganisms showed that they have strong antibacterial activity against Escherichia coli and Staphylococcus aureus and antifungal activity against Candida albicans. The minimum inhibitory concentrations for E. coli, S. aureus and C. albicans were 0.125, 0.125 and 0.250 ?g/mL, respectively. The results confirmed that Prunus armeniaca leaf extract could be used to produce AgNPs with efficient antimicrobial activity.
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    Factors influencing the water consumption behaviors of the medical students at Inonu University
    (2017) Mete, Burak; Pehlivan, Erkan; Baran, Ayşe; Çelik, Duygu; Nacar, Erkay; Çakmak, Esin
    Abstract: In this study, the purpose is to determine the water consumption behaviors of Faculty of Medicine students at Inonu University, and to compare these behaviors with some socio-demographical properties. Method: This study was organized in cross-sectional design, and was conducted on 431 students in April 2016 with face-to-face interview method. The questionnaire form consisted of two parts. In the Factor Query part of the questionnaire, there were questions that interrogated the water consumption habits of the students and their socio-demographic properties; and in the Phenomenon Query Part of the study, the Water Consumption Behaviors Scale (WCBS) consisting of 16 items was included. The minimum point that could be received from the scale, which was evaluated in five sub-categories, was 16, and the maximum point was 80. Results: 48,4% of the participants were male; and 51,6% were female. 15,7% consumed water less than one litter a day; 39% consumed between 1-1,5 liter; 24,9% consumed between 1,5-2 liter, 13,8% consumed between 2-2,5 liter; and 6,5% consumed between 2,5-3 liter a day. The average point received from the water consumption scale (47.12±10.13) was as much as 59% of the total points. Conclusions: It was found in the study that the daily water consumption of the students from Faculty of Medicine was inadequate, and the behavior norms of these students that covered the areas like water management, water pollution, and the conscious of taking the personal and social responsibility were at medium level
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    Metalik nanopartiküllerin biyolojik sentezi
    (İnönü Üniversitesi, 2017) Baran, Ayşe
    Metalik nanopartiküller tıp ve biyoteknoloji gibi çeşitli uygulamalar için kullanılabilirler. Fiziksel, kimyasal ve biyolojik yöntemler kullanılarak elde edilebilirler. Kimyasal ve fiziksel yöntemler çevre dostu değildir. Bu yüzden biyolojik metodlar diğerlerinden daha avantajlıdır. Gümüş nanopartiküller gibi nanopartikülleri bakteri, fungus, alg ve bitkiler sentezlerler. Bu çalışmada gümüş nanopartiküller indirgeyici ajan olarak Prunus armeniaca yaprak özütü kullanılarak sentezlenmiştir. Biyolojik olarak sentezlenmiş gümüş nanopartiküllerin karakterizasyonu Yüksek çözünürlüklü transmisyon elektron mikroskobu (HR-TEM), X-ışını kırınımı (XRD) ve enerji dağılımlı X-ışını (EDX) analizleri ile yapılmıştır. Renk değişimi 422 ve 427 nmde ki absorbsiyon pikleri gümüş nanopartiküllerin oluşumunu göstermiştir. Nanopartiküllerin kristal yapısı XRD analizi ile doğrulanmıştır. TEM analizi gümüş nanopartiküllerin genellikle küresel şekilli ve ortalama 24 nm partikül boyutunda olduğunu göstermiştir. Bu nanopartiküller gram negatif Escherichia coli, gram pozitif Staphylococcus aureus ve Candida albicans mayası üzerinde antimikrobayal etki göstermiştir. E. coli, S. aureus ve C. albicans için minimum inhibisyon konsantrasyonu sırası ile 0.125, 0.125 ve 0.250 μg /mL olarak bulunmuştur.