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Öğe Cortisol Awakening Response, Ovarian Steroids and Premenstrual Symptoms in Healthy Premenopausal Women(Wiley-Blackwell, 2016) Ozgocer, Tuba; Ucar, Cihat; Yildiz, Sedat; Barutcu, Ozlem[Abstract Not Available]Öğe The Effect of Daily Activities on the Activity of Stress Axes in Preschool Children(Wiley, 2023) Cevizci, Hediye; Barutcu, Ozlem; Cevizci, Nuri; Ozgocer, Tuba; Ucar, Cihat; Yildiz, Sedat; Gul, Mustafa[Abstract Not Available]Öğe Effects of Half- or Whole-Night Shifts on Hypothalamo-Pituitary-Adrenal Axis and Autonomic Nervous Systems in Women(Karger, 2021) Cakan, Pinar; Yildiz, Sedat; Barutcu, Ozlem; Ucar, Cihat[Abstract Not Available]Öğe Effects of Metformin on Diabetic Neuropathy in Diabetic Rat Model(Wiley-Blackwell, 2015) Tanbek, Kevser; Alcin, Ergul; Yildiz, Azibe; Vardi, Nigar; Koksal, Burcu; Barutcu, Ozlem[Abstract Not Available]Öğe Investigation of Possible Effects of Exendin-4 during Exposure to Mild Chronic Stress on Dehydroepiandrosterone-Induced Polycystic Ovary Syndrome in Rats(Univ Nis, Fac Medicine, 2020) Koksal, Burcu; Yildiz, Sedat; Ozgocer, Tugba; Yildiz, Azibe; Vardi, Nigar; Barutcu, OzlemThe purpose of the study was to investigate the effects of Exendin-4 on polycystic ovary syndrome (PCOS) in rats in chronic mild stress medium. For establishing the PCOS model, dehydroepiandrosterone (DHEA) (6mg/100g) in 0.2ml sesame oil was injected subcutaneously to 21-day old rats (n = 67). In addition, 0.2ml sesame oil was injected subcutaneously to the rats in groups involving solution injection only. At the initial stage of the study, the rats were grouped as control, solution and PCOS, whereas stress and Exendin-4 groups were also added in the second stage of the study. In PCOS groups, Exendin-4 was applied intraperitoneally (10 mu g/kg/day) in mild chronic stress medium for four weeks. The results revealed that weight, fasting blood glucose, fasting blood insulin and HOMA-IR levels in the rats with PCOS were significantly higher than in the other groups; also, corticosterone levels of stress groups were significantly higher than in the other groups. In addition, harmful effects of PCOS on ovarian tissues were observed in histological examinations. However, after Exendin-4 application in PCOS groups, weight, fasting blood glucose, fasting blood insulin, HOMA-IR and LH/FSH levels were decreased, whereas Exendin-4 application in PCOS group treated with stress was not as effective as the application of Exendin-4 on rats with PCOS. Exendin-4 application also increased the number of healthy follicles in PCOS group, whereas there was no change in the number of healthy follicles in PCOS+Stress group.Öğe Investigation of Possible Effects of Exendine During Exposure to Moderate Chronic Stress in Dehydroepiandrosterone-induced Polycystic Ovary Syndrome in Rats(Wiley-Blackwell, 2016) Koksal, Burcu; Alcin, Ergul; Ozgocer, Tuba; Yildiz, Azibe; Vardi, Nigar; Barutcu, Ozlem; Yildiz, Sedat[Abstract Not Available]Öğe Measurement of Salivary Alpha-amylase Activity in Professional Archers by Two Different Methods(Wiley, 2017) Barutcu, Ozlem; Kayacan, Yildirim; Derebasi, Deniz Gunay; Yildiz, Sedat[Abstract Not Available]Öğe Salivary Alpha Amylase Enzyme as a Stress Parameter: Establishment and Comparison of Laboratory Methods(Galenos Publ House, 2024) Barutcu, Ozlem; Yildiz, SedatAim: Salivary alpha ( alpha )-amylase enzyme is a biomarker used to measure sympathetic nervous system activity. This study aimed to establish three existing methods for measuring salivary alpha- amylase enzyme activity in the laboratory and to compare these methods in terms of their usability. Materials and Methods: alpha- amylase enzyme activity can be measured in ready-made kits by three methods: Starch-Iodine, 2-chloro-4-nitrophenyl maltotrioside (CNPG3) and dinitrosalicylic acid (DNS) methods. In this context, standard curves were created in the laboratory for manual study of these methods and their advantages and disadvantages were presented. The usability of these methods was tested. Results: The starch-iodine and CNPG3 methods were successfully established. However, although a standard curve was successfully established for the DNS method, this assay was not suitable for the studies as the samples were not readable and had many disadvantages. The test sensitivities and working ranges were appropriate for the starch-iodine and CNPG3 tests, requiring 4,000-fold dilution for the starch-iodine test and 5-fold dilution for the CNPG3 test. A weak but statistically significant positive correlation was observed between the two tests (R2=0.048 for linear regression; p<0.05, R2=0.106 for quadratic regression; p<0.01). Conclusion: The CNPG3 and starch-iodine methods were feasible, cost-effective, accessible, and time-efficient. The starch-iodine method is a cheaper but the CNPG3 method is also a practical test with fewer steps. In this respect, it has been decided that the CNPG3 method is the most effective method in studies based on salivary alpha- amylase enzyme method.Öğe Salivary Cortisol Levels in Hungry Fasting Individuals at the First Week of Ramadan(Wiley-Blackwell, 2016) Ozgocer, Tuba; Ucar, Cihat; Yildirim, Hilal; Cakan, Pinar; Barutcu, Ozlem; Yildiz, Sedat[Abstract Not Available]Öğe Usage of Alpha-amylase Measurement Methods in Saliva Analyses(Wiley, 2017) Barutcu, Ozlem; Yildiz, Sedat[Abstract Not Available]
