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    Assessment of atrial conduction time in patients with behçet's disease
    (Sociedade Portuguesa de Reumatologia, 2014) Cansel M.; Yagmur J.; Taşolar H.; Karincaoglu Y.; Ermis N.; Acikgoz N.; Bayramoglu A.
    Objective: Behçet's disease is characterized by increased inflammatory activity, and there there might be an increased risk of atrial arrhythmia in patients with this disease. Our study is aimed to evaluate a novel method of measuring atrial electromechanical features expressed as interatrial and intraatrial electromechani - cal delay by tissue Doppler echocardiography in patients with Behçet's disease. Methods: We evaluated 57 patients (mean age: 36.3±12.1 years) with Behçet's disease and 34 sex and age matched healthy volunteers (mean age: 38.4±8.6 years) as control group. P-wave dispersion (PWD) was calculated from the 12-lead surface ECG, interatrial and intraatrial electromechanical delay were measured by tissue Doppler imaging and conventional echocardiography. Results: Interatrial electromechanical delay and intraatrial electromechanical delay were prolonged in patients with active Behçet's disease compared with the patients with inactive disease and the controls (p<0.0001, p<0.0001, p=0.013 and p=0.001, respectively). Erythrocyte sedimentation rate and high-sensitivity C-reactive protein values of of patients with active Beh - çet's were significantly higher than those with inactive Behçet's disease and the controls (p<0.0001 and p<0.0001, respectively). High-sensitivity C-reactive protein and erythrocyte sedimentation rate were correlated with interatrial electromechanical delay in patients with Behçet's disease (r=0.44, p=0.001 and r=0.64, p<0.0001, respectively). Conclusions: The prolongation of atrial electrome- Mehmet Cansel1, Julide Yagmur1,Hakan Tasolar1, Yelda Karincaoglu2,Necip Ermis1,Nusret Acikgoz1, Adil Bayramoglu1, Omur Otlu1 ,Ferhat Eyyüpkoca1, Hasan Pekdemir1, Ramazan Ozdemir1 chanical conduction might be related with changes in structure and electrophysiological properties of the atrial myocardium or the conduction system in patients with active Behçet's disease.n time in patients with Behçet's disease.
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    The organization of the somatic cell nuclei within the oculomotor nuclear complex in rats
    (2002) Aktekin M.; Aldur M.M.; Bayramoglu A.; Atasever A.; Ozturk A.H.; Basar R.
    Although there is detailed knowledge on the organization of the motor neurons supplying the extraocular muscles, there are still some discrepancies concerning the results of different studies. This study is planned to reexamine the distribution of the motor neurons in the oculomotor nucleus of the rat. In the present study we used 20 young adult Sprague-Dawley rats in four groups which represent four extraocular muscle groups innervated by oculomotor nerve, namely medial rectus, inferior rectus, superior rectus and inferior oblique muscle groups. For each rat 1-2 ?l of 30% Horseradish Peroxidase (HRP) is used as a tracer. Multiple injections were made to fully infiltrate the individual muscles. After determining the position of the medial rectus subgroup, injections were applied into more than one muscle in a single experiment in order to decide the proper localization of the motor neuron subgroups in relation to each other. For each of the muscle groups five rats were injected with HRP. The rostral end of the nucleus begins with a compact neuron group belonging to medial rectus subgroup. However, at the caudal end the neurons were scattered in a wider area gradually decreasing in number. Neurons innervating the medial rectus muscle were located ipsilaterally within the ventral and ventrolateral portions of the nucleus extending throghout its rostrocaudal length. Motoneurons belonging to the inferior rectus subgroup were observed ipsilaterally within the gap between the median raphe and medial end of the medial rectus subgroup. Motoneurons of the inferior oblique subgroup formed an ovoid cell mass ipsilaterally and slightly dorsal to the medial and inferior rectus subgroups. Neurons of the superior rectus subgroup were localized contralaterally within the caudal two thirds of the nucleus. The neurons of this subgroup were located at the ventral and ventromedial parts of the inferior oblique subgroup and dorsal to the inferior and the medial rectus subgroups. © neuroanatomy.org.