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    Anatomic and functional outcomes of three-day face down positioning after idiopathic macular hole surgery
    (Gazi Eye Foundation, 2013) Do?anay S.; Bilak S.; Kütükde D.
    Purpose: To evaluate anatomical and functional results of patients with idiopathic macular holes (MH) prospectively, after pars plana vitrectomy (PPV), internal limiting membrane (ILM) peeling, gas endotamponade and postoperative three day prone positioning. Materials and Methods: Sixteen eyes 16 patients with idiopathic MH were enrolled to the study. 23-gauge pars plana vitrectomy, internal limiting membrane peeling and intraocular gas endotamponade injection were performed in all eyes. PPV combined with cataract surgery in phakic cataractous eyes. Three-day prone positioning was recommended to all patients. MH closure, best corrected visual acuity (BCVA), intraocular pressure (IOP) and complications were evaluated postoperatively. Results: Postoperative mean follow-up period was 15.93±10.22 months. The mean age of the patients was 66.68±12.02 (28-81). MH was stage 2 in 3 eyes (18.8%), stage 3 in 3 eyes (18.8%), and stage 4 was in 10 eyes (62.5%). MH was closed in 15 eyes (93.8%) after surgery. Preoperative BCVA was 0.15±0.10 (Snellen) and postoperative BCVA was 0.28±0.26 (p=0.005). Visual improvement was found in 11 patients (68.0%). The mean IOP values were 13.81±1.22 mmHg prior to surgery, and 13.68±1.62 mmHg, 14.06±1.48 mmHg, and 14.12±0.95 mmHg 1 day, 1 month and 3 months after surgery respectively (p>0.05). Conclusion: Successful anatomical and functional results can be obtained in patients with idiopathic MH after PPV, ILM peeling, gas endotamponade injection and postoperative three-day prone positioning. No significant complications were observed after surgery.
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    The effect on surgical success of intravitreal bevacizumab given before pars plana vitrectomy in diabetic patients
    (2010) Do?anay S.; Koç B.; Çankaya C.; Düz C.; Bilak S.
    Purpose: To investigate the effect on surgical success of intravitreal bevacizumab given before pars plana vitrectomy in diabetic patients. Materials and Methods: All patients were divided into two groups: those given bevacizumab before surgery (Group 1; 32 patients) and those not given bevacizumab (Group 2; 50 patients). The groups were compared with regard to the frequencies of retinal tear and active bleeding during surgery, postoperative changes in best corrected visual acuity (BCVA) and intraocular pressure (IOP), postoperative frequencies of retinal detachment and recurrent vitreous hemorrhage (VH), and development of rubeosis. Results: During the surgery, retinal tear was observed in 2 patients (6.3%) from Group 1 and in 4 patients (8%) from Group 2; active bleeding was seen in 2 patients (6.3%) from Group 1 and in 4 patients (8%) from Group 2. After the surgery, retinal detachment was found in 1 patient (3.1%) from Group 1 and in 2 patients (4%) from Group 2; recurrent VH was found in 4 patients (12.5%) from Group 1 and in 14 patients (28%) from Group 2. In the postoperative controls, an increase in IOP was determined in 6 patients (18.8%) from Group 1 and in 9 patients (18%) from Group 2. In the postoperative controls, an increase in the mean BCVA value was determined in 24 patients (75%) from Group 1 and in 32 patients (64%) from Group 2. Conclusion: In the patients with PDR, anti-VEGF (vascular endothelial growth factor) drugs positively influence the surgical success by causing the active new vasculature to be regressed and consequently allowing easy cleaning of the membranes during surgery. Due to the anti-inflammatory and anti-edematous effect of anti-VEGF drugs, better BCVA is obtained after surgery.