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Öğe Caffeine intake in adults with cardiovascular diseases; A cross-sectional study(Sage Publications Inc, 2024) Bozkir, Cigdem; Tuggum, Sergen; Kagan, Nursena; Nizam, Beydanur; Alpsoy, SerefBackground: Caffeine in the safe dose range has been associated with a reduction in the risk of chronic diseases. There is evidence that caffeine intake has both protective and negative effects on cardiovascular diseases. Aim: This study aimed to investigate caffeine intake in cardiovascular patients. Methods: The study sample was selected from individuals who applied to the Cardiology policlinic of Tekirdag Namik Kemal University Hospital. A questionnaire was applied using face-to-face interview method to determine their demographic information, nutritional status and anthropometric measurements. Moreover, the nutritional status of the participants was determined by the Food Frequency Questionnaire and the type of cardiovascular disease was determined by a physician. The blood parameters of the sample for the last three months were questioned. The sample has been ninety people of whom fifty cardiovascular diseases (CVDs) were diagnosed and forty were non-diagnosed (ND). Results: The mean age of individuals (n = 90) was 43.2 +/- 14.4. The BMI and waist circumference of the CVDs group were statistically significantly higher than the ND group (p < 0.001). While the total caffeine consumption of the ND group was 209.34 +/- 143.85 mg/day, consumption of the CVDs group was 209.99 +/- 196.76 mg/day. LDL cholesterol and total cholesterol did not show statistically significant difference between the two groups. However, HDL cholesterol was significantly higher in the ND group (p <= 0.001). Conclusion: Present results show that daily caffeine consumption may partially affect blood parameters associated with cardiovascular diseases, especially in the presence of coronary artery disease.Öğe Communication Skills, Empathic Tendency and Affecting Factors of Assistant Doctors in Inonu Universty, Faculty of Medicine, Malatya(Medicine Science, 2015) Bozkir, Cigdem; Tekin, Cigdem; Mete, Burak; Nacar, Erkay; Ozer, AliÖz: Bu araştırma, Malatya İnönü Üniversitesi Tıp Fakültesinde ihtisas yapan asistan doktorların iletişim becerileri ve empatik eğilim düzeylerini belirlemek amacıyla yapılmış tanımlayıcı tipte bir araştırmadır. Araştırma, 2013 yılı Ekim-Aralık döneminde, Malatya İnönü Üniversitesi Tıp Fakültesinde ihtisas yapan 261 asistan doktor üzerinde gerçekleştirilmiştir. Çalışmada araştırmacı tarafından geliştirilen, demografik özellikler ile çalışma düzenlerini sorgulayan anket formu ve Balcı (1996) tarafından geliştirilmiş olan iletişim becerileri ölçeği (İBÖ) ve Dökmen tarafından geliştirilen empatik eğilim ölçeği (EEÖ) kullanılmıştır. Veriler, SPSS paket programı kullanılarak analiz edilmiştir. İstatistiksel analizlerde, yapılan Kolmogorov-Smirnov test (K-S) ile normal dağılıma uyan veriler için Student t ve One Way Anova testleri kullanılmış, normal dağılıma uymayan veriler için ise Mann-Whitney U ve Kruskall Wallis testleri kullanılmış ve tüm değerlendirmelerde p<0.05 düzeyi anlamlı kabul edilmiştir. Araştırmaya katılan asistanların %41.8'i kadın, %58.2'si erkektir. Araştırmaya katılan asistan doktorların sosyo demografik özelliklerine göre iletişim becerileri ölçeği ve alt ölçeklerinden aldıkları puanlarda anlamlı bir farklılık bulunmamıştır (p>0.05). Empatik eğilim ölçeğinden alınan puan ortalamaları, temel bilimlerde çalışanlarda; 61.33±5.50, dâhili bilimlerde çalışanlarda; 63.54±7.38, cerrahi bilimlerde çalışanlarda ise 64.00±5.76 olup aradaki farklılık istatiksel olarak anlamlı bulunmamıştır (p> 0.05). Araştırmaya katılan asistan doktorların empatik eğilim ölçeği ve iletişim becerileri ölçeği puanları arasında anlamlı bir korelasyon bulunmuştur (r=0,276; p<0.01). Elde edilen bu değerler sonucunda İnönü Üniversitesi Tıp Fakültesi asistan hekimlerinin iletişim becerileri ve empatik eğilim düzeylerinin "orta düzey" olduğu, temel bilimlerde çalışan hekimlerin çalışma ortam memnuniyetlerinin daha yüksek olduğu saptanmıştırÖğe Effect of the COVID-19 Pandemic on the Psychological Health of Patients Who Underwent Liver Transplantation Due to Hepatocellular Carcinoma(Mdpi, 2023) Akbulut, Sami; Kucukakcali, Zeynep; Saritas, Hasan; Bozkir, Cigdem; Tamer, Murat; Akyuz, Musap; Bagci, NazlicanBackground: The primary aim of this study was to compare liver transplant (LT) recipients with and without hepatocellular carcinoma (HCC) in terms of COVID-19-related depression, anxiety, and stress. Method: A total of 504 LT recipients with (HCC group; n = 252) and without HCC (non-HCC group; n = 252) were included in the present case-control study. Depression Anxiety Stress Scales (DASS-21) and Coronavirus Anxiety Scale (CAS) were used to evaluate the depression, stress, and anxiety levels of LT patients. DASS-21 total and CAS-SF scores were determined as the primary outcomes of the study. Poisson regression and negative binomial regression models were used to predict the DASS and CAS scores. The incidence rate ratio (IRR) was used as a coefficient. Both groups were also compared in terms of awareness of the COVID-19 vaccine. Results: Poisson regression and negative binomial regression analyses for DASS-21 total and CAS-SF scales showed that the negative binomial regression method was the appropriate model for both scales. According to this model, it was determined that the following independent variables increased the DASS-21 total score: non-HCC (IRR: 1.26; p = 0.031), female gender (IRR: 1.29; p = 0.036), presence of chronic disease (IRR: 1.65; p < 0.001), exposure to COVID-19 (IRR: 1.63; p < 0.001), and nonvaccination (IRR: 1.50; p = 0.002). On the other hand, it was determined that the following independent variables increased the CAS score: female gender (IRR:1.75; p = 0.014) and exposure to COVID-19 (IRR: 1.51; p = 0.048). Significant differences were found between the HCC and non-HCC groups in terms of median DASS-21 total (p < 0.001) and CAS-SF (p = 0.002) scores. Cronbach's alpha internal consistency coefficients of DASS-21 total and CAS-SF scales were calculated to be 0.823 and 0.783, respectively. Conclusion: This study showed that the variables including patients without HCC, female gender, having a chronic disease, being exposed to COVID-19, and not being vaccinated against COVID-19 increased anxiety, depression, and stress. High internal consistency coefficients obtained from both scales indicate that these results are reliable.Öğe Evaluation of vaspin and irisin hormones levels in diabetic rats and relationship with diet(Ios Press, 2022) Tuggum, Sergen; Bozkir, Cigdem; Aslan, Serkan; Yilmaz, Ahsen; Celikkol, AliyeBACKGROUND: Type-2 diabetes with an increasing prevalence is a public health problem. Irisin and vaspin, which are secreted a majority from adipose tissue, are discovered hormones recently, and their effects on diabetes are studied. OBJECTIVE: This study aims to the effects of diet on these hormones levels in diabetic rats. METHODS: In this study, ten-week-old 18 Wistar-Albino rats were divided into three groups randomly. The diabetic group (n = 6) was fed a high-fat diet (HFD). Other rats were divided into two control groups, one of them (n = 6) was fed a control diet (CD), and the other group (n = 6) was fed HFD. The feeding time for all groups was 4 weeks. Streptozotocin (STZ) was used for diabetes induction in rats. RESULTS: At the end of the four weeks, the body weight of the diabetic group decreased significantly. In the diabetic group compared to the control groups, it was observed that besides high fasting blood glucose (FBG), triglyceride, total cholesterol levels, and insulin resistance (HOMA-IR) scores. Vaspin levels were significantly higher in diabetic rats, while irisin levels were similar between groups. Besides, vaspin level correlation with biochemical parameters such as glucose, triglycerides, total cholesterol, and HOMA-IR score was significant. CONCLUSION: In conclusion, this study showed that besides the evidence that vaspine is a hormone associated with diabetes, diet composition could give an opinion about the type-2 diabetes process by looking at hormone levels.Öğe Prevalence of obesity and affecting factors in physically disabled adults living in the city centre of Malatya(Bmj Publishing Group, 2016) Bozkir, Cigdem; Ozer, Ali; Pehlivan, ErkanObjective: The purpose of this study was to investigate the prevalence of obesity, and the risk factors associated with it, in physically disabled adults living in the city centre of Malatya, Turkey. Method: This research was designed as a cross-sectional study conducted on physically disabled people aged 20-65 years living in the city centre of Malatya. The prevalence of obesity in disabled people was within 95% CIs, the power was calculated as 80%, and the sample size of our population was calculated as 258 individuals. Results: The prevalence of obesity was found to be 13.2%. The relationship between disability type and obesity status was found to be significant. The prevalence of obesity was 21.3% in visually impaired people, 17.9% in speech-impaired people, 17.8% in hearing-impaired people and 6.5% in orthopaedically disabled people. Conclusions: Educational interventions on nutrition and lifestyle can be effective considering the high prevalence of obesity in visually impaired people, the prevalence of weakness in orthopaedically disabled people and the risk related to the area in which body fat is localised even when body mass index is within the normal range. Training disabled people in sports appropriate to their disability type and building appropriate facilities for those sports might have a positive effect.
