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  • Küçük Resim Yok
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    The Association of Gene Polymorphisms Linked to Caffeine Use with Athletic Performance
    (Gazi Univ, Fac Med, 2023) Yildirim, Selin; Bulgay, Celal; Ergun, Mehmet Ali; Eken, Ozgur; Ceylan, Halil Ibrahim; Nobari, Hadi; Cerit, Mesut
    Caffeine's use as a performance-enhancing supplement among professional athletes progressively increased after it was taken off the World Anti-Doping Agency's (WADA) list of banned substances. The present review looks at the interactions caused by different levels of caffeine ergogenicity in athletes and gene polymorphisms that affect caffeine ergogenic effect in the current literature. Therefore, a comprehensive analysis of the studies available in the literature and the respective study results have evaluated caffeine ergogenicity in athletes and gene polymorphisms. The search for studies was performed through five databases. Individual responses to caffeine consumption may differ from person to person due to multigene and multifactorial interactions. Adenosine A2A receptor (ADORA2A) and Cytochrome P450 1A2 (CYP1A2) are two genes thought to have the most effects on caffeine's ergogenicity. The function of these two genes accounts for most inter-individual variations in studies after caffeine ingestion. Based on the findings, it is understood that the contribution of caffeine use to individual performance development varies over time due to changes in both environmental and epigenetic interactions, as well as parameters such as circadian rhythm, training loads, nutritional routine, habitual caffeine use, drug intake, expectation, time of consumption, and heredity. As a result, individual caffeine responses are highly complex and involve multiple modifiers.
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    Elit seviyedeki güreşçilerin bacak kuvvetleri ve denge performansları arasındaki ilişkinin incelenmesi
    (İnönü Üniversitesi, 2017) Bulgay, Celal; Polat, Sezen Çimen
    ÖZET Bu çalışmada, elit güreşçilerin bacak kuvveti ve denge performansları arasındaki ilişkisinin incelenmesi amaçlanmıştır. Araştırma grubunda yaşları (19,09±0,30) yıl, boy uzunlukları (163,46±7,33) cm ve vücut ağırlıkları (72,43±15,06) kg olan 20 elit serbest güreşçi yer almıştır. Güreşçilerin bacak kuvvetleri ve denge performanslarını belirlemek için yapılan laboratuvar testleri boy uzunluğu, vücut ağırlığı, y denge testi, izokinetik bacak kuvveti (Isomed-2000) şeklinde yapılmıştır. Araştırmada elde edilen veriler ortalama ve standart sapma şeklinde sunulmuştur. Normallik sınaması Shapiro-Wilk testi ile gerçekleştirilmiştir. Normal dağılım gösteren tüm parametreler içinde Pearson Korelasyon testi yapılmıştır. Anlamlılık düzeyi p<0,05 kabul edilmiştir. Araştırmada yer alan güreşçilerin sol bacak hamstring ve quadriceps kuvvetiyle, sol bacak posterolateral ve posteromedial denge performansları arasında istatistiksel olarak anlamlı bir ilişki saptanmıştır. Sonuç olarak elde edilen veriler değerlendirildiğinde, araştırma grubunda yer alan serbest güreşçilerde üst bacak kuvvet değerlerinde sağ bacak da bir ilişki gözlenmezken sol bacak da denge performansında kuvvetin etkili olabileceğini görmekteyiz. Anahtar Kelimeler: Serbest Güreş, Kuvvet, Denge
  • Küçük Resim Yok
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    Evaluation of the Association of VDR rs2228570 Polymorphism with Elite Track and Field Athletes' Competitive Performance
    (Mdpi, 2023) Bulgay, Celal; Bayraktar, Isik; Kazan, Hasan Huseyin; Yildirim, Damla Selin; Zorba, Erdal; Akman, Onur; Ergun, Mehmet Ali
    The present study aimed to examine the vitamin D receptor (VDR), rs2228570 polymorphism, and its effect on elite athletes' performance. A total of 60 elite athletes (31 sprint/power and 29 endurance) and 20 control/ physically inactive, aged 18-35, voluntarily participated in the study. The International Association of Athletics Federations (IAAF) score scale was used to determine the performance levels of the athletes' personal best (PB). Whole exome sequencing (WES) was performed by the genomic DNA isolated from the peripheral blood of the participants. Sports type, sex, and competitive performance were chosen as the parameters to compare within and between the groups by linear regression models. The results showed no statistically significant difference between the CC, TC, and TT genotypes within and between the groups (p > 0.05). Additionally, our results underlined that there were no statistically significant differences for the association of rs2228570 polymorphism with PBs within the groups of the (p > 0.05) athletes. The genetic profile in the selected gene was similar in elite endurance, sprint athletes, and in controls, suggesting that rs2228570 polymorphism does not determine competitive performance in the analyzed athlete cohort.