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Öğe Advanced Magnetic Resonance Imaging Findings of Renal Hydatid Cyst(2014) Erdem, Gülnur; Burulday, Veysel; Alkan, AlpayAbstract: Hydatid Cyst, a serious health problem in the developing countries, is a zoonotic infection formed by echinococcus. Though liver or lung involvement is often, kidney involvement is rarely seen and represents for only 2 to 3 per cent of all cases of hydatid disease. An adult case referred who had multiple cysts in liver and large, solitary cyst in the kidney. We aimed to present magnetic resonance spectroscopy (MRS) and diffusion weighted magnetic resonance (DWI) findings of the hydatid cyst's. This is the first study that shows the MRS and DWI results of the renal hydatid disease. The mean ADC (apparent diffusion coefficient) value of the renal hydatid cyst was 2554x10-6 mm2/s on DWI and high signal intensity was detected compared with the renal parenchyma. MR spectroscopy at TE of 31 shows prominent alanine peak in addition to small amino acid peaks. Advanced MRI studies such as DWI and MRS can provide supplementary information both in the post-treatment period and in the diagnosis by bringing non-invasive approaches.Öğe Effects of contrast material on the metabolite ratios in single-voxel MR Spectroscopy of intraaxial brain tumors(Churchill Livingstone, 2012) Alkan, Alpay; Burulday, Veysel; Oztanir, Namik; Dogan, Metin; Erbay, Mehmet Fatih; Kocak, Ayhan; Aralasmak, AyseAim: The purpose of our study was to determine whether the administration of contrast material affects the results of MR Spectroscopy (MRS) in different intraaxial brain tumors. Materials and methods: Thirty-three patients (median range 46.72 +/- 2.95, range 9-77) with intraaxial brain tumors underwent MRS before and 5 min after intravenous administration of gadolinium based contrast material at the standard dose of 0.1 mmol/kg (Gadodiamide or Gd-DOTA). Metabolite ratios (N-acetyl aspartate (NAA)/Creatine (Cr), Choline (Cho)/Cr. and NAA/Cho) were calculated. Results: There was no significant difference between the pre and postcontrast MRS spectra as regards to NAA/Cr (p:0.4), Cho/Cr (p:0.2), and NAA/Cho (p:0.2) ratios obtained from the intraaxial brain tumors. Conclusion: Contrast material administration did not change the metabolite ratios of MRS. Contrast administration would be useful in guiding voxel localization in MRS evaluation of intraaxial brain tumors. (C) 2012 Elsevier Ltd. All rights reserved.Öğe Kadın pelvik kitlelerinin benign-malign ayırımında difüzyon ağırlıklı MRG bulgularının farklı `b' değerleri kullanılarak değerlendirilmesi(İnönü Üniversitesi, 2010) Burulday, VeyselBu çalışmanın amacı, jinekolojik pelvik kitle ön tanısı almış kadın hastalarda kitlelerin farklı `b' değerleri kullanarak difüzyon ağırlıklı MRG bulgularının tanıya katkısını araştırmaktır. Çalışmaya Ekim 2009 ile Kasım 2010'da, Radyoloji Anabilim Dalı MR Ünitesi'ne pelvik kitle ön tanısıyla pelvik MR tetkiki istenen 15?82 (ort: 43) yaş aralığında 167 malign ve benign lezyon içeren 154 olgu dahil edildi. Bu hastalardan DAG ile sırasıyla b250, b500, b750, b1000 gradient değerlerinde difüzyon ağırlıklı EPI görüntüler alındı. Pelvik kitle saptanan olgularda lezyonlardan ADC değerleri ölçüldü. Malign lezyon saptanan 47 olgunun ortalama ADC değerleri (b250, b500, b750, b1000) (1.19x10?3, 1.12x10?3, 1.05x10?3, 0.94x10?3 sn/mm2), benign lezyon saptanan 120 olgunun ortalama ADC değerlerinden (b250, b500, b750, b1000) (2.17x10?3, 2.04x10?3, 1.97x10?3, 1.94x10?3 sn/mm2) düşük ölçüldü ve istatistiksel olarak anlamlı bulundu (p<0,05). Çalışmamız farklı b değerlerinde planlanmış olup tüm değerlerde malign ve benign kitleler arasında anlamlı istatistiksel farklar bulundu. Ancak b 500 altı değerlerde görüntü rezolüsyonu azaldığını ve lezyonların saptanmasının güçleştiğini saptadık. Pelvik bölge değerlendirmelerinde b 500 ile b 1000 arası değerlerin kullanılmasının daha uygun olacağının kanaatindeyiz. Sonuç olarak DAG'ın, konvansiyonel görüntüleme yöntemlerine eklenerek rutin kullanıma girmesinin pelvik kitlelerin malign ve benign ayırıcı tanısında önemli katkılar sağlayacağını düşünmekteyiz.Öğe Kronik Böbrek Yetmezliğine Bağlı Gelişen Posterior Lökoensefalopati: Manyetik Rezonans Görüntüleme Bulguları(İnönü Üniversitesi Tıp Fakültesi Dergisi, 2010) Burulday, Veysel; Erbay, Mehmet Fatih; Doğan, Metin; Göktan, Aslı; Alkan, AlpayPosterior reversibl ensefalopati sendromu çocuklarda nadir olarak görülen klinik ve radyolojik bir sendrom olup hipertansif ensefalopati, böbrek yetmezliği, immunsupresif ilaçlarla tedavi, sıvı retansiyonu, eklampsi, ve transfüzyon başlıca etiyolojik nedenler arasındadır. Bu raporda, dört yıldır kronik böbrek yetmezliği nedeniyle takip edilen, nöbet geçirme ve hipertansif atak ile çocuk polikliniğine başvuran ve yapılan MRG incelemesinde posterior reversible ensefalopati tanısı konulan yedi yaşındaki bir kız hastanın tanı ve takip MRG inceleme bulguları sunulmaktadır. Hastanın takip MRG incelemesinde posterior reversibl ensefalopati sendromunun olası komplikasyonlarından olan kanama gelişmiştir. Nöbet ile gelen hipertansif çocuklarda ayırıcı tanıda posterior reversibl lökoensefalopati sendromu düşünülerek beyin MRG ve difüzyon MRG incelemesi rutin olarak yapılmalıdır.Öğe Noticable Findings in Cranial MRI of the Patients with Idiopathic Intracranial Hypertension(Sage Publications Inc, 2022) Cankaya, Imran; Muluk, Nuray Bayar; Burulday, Veysel; Bilgili, M. Yasemin Karadeniz; Ozdemir, AdnanObjectives Idiopathic intracranial hypertension (IIH) is characterized by increased intracranial pressure. We investigated the optic nerve, Meckel's cavity, internal carotid artery (ICA) and pituitary findings of IIH by Cranial Magnetic Resonance Imaging (MRI). Methods Cranial MRI images of 35 adult patients with IIH and 35 adult subjects with normal cranial MRI results (control) were evaluated. Optic nerve diameter (OND), optic nerve sheat diameter (ONSD), OND/ONSD ratio, ON tortuosity, ON protrusion, posterior scleral flattening, ICA transverse diameter, CSF distance in Meckel's cavity and ICA transverse diameter/CSF distance in Meckel's cavity ratio, and pituitary gland measurements (height and transverse dimension; and Optic chiasm- pituitary gland distance) were measured. Results OND and ONSD of the IIH group were significantly higher than those of the control groups at anterior and posterior measurements (p < 0.05). OND/ONSD ratio of the IIH group was lower at anterior measurement; and higher at the posterior measurement than the control group (p < 0.05). Right ICA transverse diameter and bilateral CSF distance in Meckel's cavity of the IIH group were higher than those of the control. Optic chiasm- pituitary gland distance of the IIH group was significantly higher than that of the control group (p < 0.05). Conclusion OND/ONSD ratio is different in anterior and posterior measurements. So we recommend measuring OND and ONSD separately in IIH patients to use in the clinical practice. Similarly, optic chiasm-pituitary gland distance is also another point to note for IIH patients on MRI. Our paper adds new approach to IIH in terms of OND/ONSD ratio.Öğe Possible predictive clinical and radiological markers in decision making for surgical intervention in patients with Chiari Malformation type 1(Taylor & Francis Ltd, 2022) Yuksel, Ulas; Burulday, Veysel; Akkaya, Suleyman; Baser, Selcuk; Ogden, Mustafa; Alhan, Aslihan; Bakar, BulentBackground The first aim of this study was to compare the clinical data and posterior fossa morphometry obtained during the admission to the hospital between control group individuals (who had not Chiari Malformation (CM) type 1) and CM type 1 patients treated surgically or not. The second aim was to create a valid and reliable scale that can predict the decision-making for surgical intervention simply and easily in these patients. Materials Medical data and radiological images of 70 CM type 1 patients during their admission to the hospital were compared with the data of 69 control group individuals. Results Conservative treatment and/or follow-up was applied to 58 (82.9%) patients, and 12 (17.1%) patients underwent surgery. ROC analysis showed that the presence of myelopathy, tonsillar herniation >8 mm, Chamberlain line >84 mm, McRae line >44.50 mm, and odontoid process-McRae line angle <10.50 degrees could be used as predictive markers in decision-making for surgical intervention (p < 0.05). Logistic Regression analysis revealed that symptoms severity, and McRae line value would be the 'best parameters' in decision-making for surgical intervention (p < 0.05). A scale named the CHIASURG scale developed using this study's parameters showed that the parameters of 'depth of tonsillar herniation', 'Chamberlain line', and 'McRae line' could predict the surgical intervention risk. Conclusion It was found that symptoms severity and McRae line value could be used as predictive markers in decision-making for surgical intervention. Additionally, it was concluded that a new scale called CHIASURG could predict surgical intervention risk validly and reliably.
