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    Assessment of heavy metal accumulation and essential nutrients in fruits: implications for food safety and environmental sustainability
    (Springer, 2025) Yumusakbas, Hatice; Ugur, Yilmaz; Maras, Zeynep; Buyuksoylu, Semih; Erdogan, Selim
    This study investigates the total concentrations of essential and potentially toxic elements in cherries (Prunus avium), strawberries (Fragaria x ananassa), and grapes (Vitis vinifera) to assess food safety and environmental sustainability. A total of 550 fruit samples and corresponding leaf and soil samples were collected from cherry, strawberry, and grape plants across 60 individuals, with 1 kg of soil sampled per plant. Elemental concentrations were determined using Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES). The results indicated that potassium (K) was the dominant macro element in strawberries (3242.08 mg/kg), while calcium (Ca) exhibited the highest concentration in grapes (4748.0 mg/kg). Iron (Fe) concentrations were notably high in grape soils (170.85 mg/kg), besides cadmium (Cd) concentrations exceeded permissible regulatory limits in all samples, suggesting contamination from agricultural sources. Principal Component Analysis (PCA) and Hierarchical Cluster Analysis (HCA) revealed distinct elemental patterns between fruit, leaf, and soil compartments. These findings highlight the necessity of continuous monitoring and regulatory enforcement to mitigate heavy metal exposure in agricultural products.
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    An investigation of histopathological changes and bioaccumulation in tissues of rainbow trout (Oncorhynchus mykiss) after exposure to dodine
    (Taylor & Francis Ltd, 2022) Buyuksoylu, Semih; Ozgur, Mustafa Erkan; Gul, Cemile Ceren; Taslidere, Asli; Aydemir, Songul; Erdogan, Selim
    The purpose of this research is to determine ecotoxicological effects of dodine (n-dodecylguanidini acetate) on aquatic environments. Though dodine is widely used as a fungicide in agriculture, but there is no much data about its ecotoxicology. In this regard, we investigated bioaccumulation levels and histological alterations on the tissues of muscle, liver and gills in Rainbow Trout (Oncorhynchus mykiss) against different doses (0.01, 0.1, 0.5 and 1mg/L) of Dodine exposure. The tissues of fish were extracted according to QUECHERS method and analyzed by mass spectrometer (LC-MS-MS). Neither of the applied dodine doses resulted in killing 50% of the total individuals in the experimental groups. However, 48hours after doses, behaviors such as instability, anomaly in swimming or sudden jumping movements were observed. Histological results of the study showed deteriorations of the radiological pattern of hepatocytes, sinusoidal dilatations, hemorrhages, edemas, mononuclear cell infiltrations, vascular congestions, hyperplasia and hypertrophy in liver, gill and muscle tissues. Accumulation of dodine in tissues correlated with increase of dose. The maximum level of active substance accumulation in tissues were measured 96hours after application of 1mg/L dodine dose -in order- in gills, muscles and liver. The accumulations were statistically significant (p<0.05) when compared with control group.