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Öğe THE EFFICACY AND SAFETY OF ANTI-TNF A TREATMENT IN ANKYLOSING SPONDYLITIS PATIENTS WITH LATE ONSET COMPARED TO THOSE WITH ADULT ONSET; THE DATA FROM TURKBIO REGISTRY(Bmj Publishing Group, 2019) Uslu, Sadettin; Can, Gercek; Cefle, Ayse; Yilmaz, Sema; Kocaer, Sinem Burcu; Inel, Tuba Yuce; Gulle, Semih[Abstract Not Available]Öğe The Efficacy and Safety of Anti-TNF? Treatment in Ankylosing Spondylitis Patients with Late Onset Compared to Those with Adult Onset; The Data from TURKBIO Registry(Wiley, 2019) Uslu, Sadettin; Can, Gercek; Cefle, Ayse; Yilmaz, Sema; Kocaer, Sinem Burcu; Inel, Tuba Yuce; Gulle, Semih[Abstract Not Available]Öğe The Efficacy and Safety of CT-P13 as First-line and Subsequent-line Therapy in Patients with Ankylosing Spondylitis: Real-life Data from TURKBIO Cohort(Wiley, 2022) Uslu, Sadettin; Gulle, Semih; Can, Gercek; Senel, Soner; Capar, Sedat; Dalkilic, Huseyin Ediz; Akar, Servet[Abstract Not Available]Öğe Efficacy and Safety of Secukinumab in the Treatment of Axial Spondyloarthritis: Real-Life Data from TURKBIO Cohort(Wiley, 2022) Gulle, Semih; Karakas, Ali; Can, Gercek; Senel, Soner; Capar, Sedat; Dalkilic, Huseyin Ediz; Akar, Servet[Abstract Not Available]Öğe A real-life analysis of patients with rheumatologic diseases on biological treatments: Data from TURKBIO Registry(Aves, 2022) Onen, Fatos; Can, Gercek; Capar, Sedat; Dalkilic, Ediz; Pehlivan, Yavuz; Senel, Soner; Akar, ServetObjective: TURKBIO registry, established in 2011, is the first nationwide biological database in Turkey. This study aimed to provide an overview of TURKBIO data collected by June 2018. Methods: The registry included adult patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS), nonradiographic axial spondyloarthritis (nr-AxSpA), and psoriatic arthritis (PsA). Demographic and clinical features, disease activity markers, and other follow-up parameters, current and previous treatments, and adverse events were registered electronically at each visit using open-source software. The registration of patient-reported outcome measures was carried out electronically by the patients using touch screens. Results: TURKBIO registry included a total of 41,145 treatment series with biologicals. There were 2,588 patients with axSpA (2,459 AS and 129 nr-axSpA), 2,036 with RA, and 428 with PsA. The total number of patients, including those with other diagnoses, was 5,718. In the follow-up period, the number of patients and also visits steadily increased by years. The yearly mean number of visits per patient was found to be 2.3. Significant improvements in disease activity and health assessment parameters were observed following the biological treatments. Biologics were often given in combination with a conventional synthetic disease-modifying antirheumatic drug in patients with RA. Infections were the most commonly seen adverse events, followed by allergic reactions. Tuberculosis was observed in 12 patients, malignancy in 18, and treatment-related mortality in 31. Conclusion: TURKBIO provided a valuable real-life experience with the use of biologics in rheumatic diseases in Turkey.Öğe RESULTS OF A TRAINING COURSE FOR CALCULATION OF THE MODIFIED RODNAN SKIN SCORE IN SCLERODERMA(Bmj Publishing Group, 2019) Can, Gercek; Avsar, Aydan Koken; Kocaer, Sinem Burcu; Kenar, Gokce; Solmaz, Dilek; Yarkan-Tugsal, Handan; Karadag, Duygu Temiz[Abstract Not Available]
