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    Pregnancy in women with epilepsy and monitoring: Review
    (2010) Özişik Karaman H.I.; Canbaz Kabay S.; Kamişli Ö.; Erdinç O.O.
    The prevalence of epilepsy is about 05-1.0%, and slightly less than half of those affected are women. Epilepsy is more frequent neurologocical disorder during pregnancy. Women with epilepsy that plan to become pregnant can in general look forward to uneventful pregnancies and to giving birth to normal children. Women with epilepsy do have an increased risk of certain obstetrical complications. There is an increased risk of vaginal bleeding, anemia, hyperemesis gravidarum, vitamine D and K deficiency, megaloblastic anemia, preeclampsia, eclampsia,premature labor, and postpartum bleeding. The effect of pregnancy on seizure frequency is variable and unpredictable between patients. Approximately 25% of patients have an increase in their seizures. Pregnancy is associated with several physiologic and psychologic changes that can alter seizure frequency, including changes in sex hormone concentrations, changes in antiepileptic drug metabolism, sleep deprivation, and new stresses. The risk for congenital malformations is higher in women on antiepileptic drug regimens.These risks can be reduced with appropriate prepregnancy counseling. During pregnancy, important considerations include; therapeutic drug monitoring, surveillance for obstetric complications and vigilance for seizures during the intrapartum and postpartum period. The care of pregnant women with epilepsy requires attention and close cooperation between neurologist and gynecologist is recommended. In this article we answer the questions commonly asked by epileptic patients regarding pregnancy. Copyright © 2010 by Türkiye Klinikleri.