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    Conservative, interventional and regenerative methods in chronic pain management
    (2020) Candiri, Busra; Talu, Burcu
    Pain is a complex condition that affects an individual physically, mentally and socially and in which clinicians find it difficult to cope. In particular, the impact of chronic pain on patients’ lives can range from small restrictions to complete loss of independence. Therefore, there are many applications for improving the quality of life of individual and controlling the pain. In recent years, a better understanding of the physiological and chemical mechanisms involved in chronic pain has gained pain management many new treatment methods. These are starting from non-invasive treatment methods such as physiotherapy, manual therapy, emotional therapy, and progressing to more invasive methods such as spinal cord stimulation and deep brain stimulation. Although current advances have taken effective steps in chronic pain control, more comprehensive research is needed on the effectiveness of these treatments and in which situations they are used in coping with pain. In this review, we aimed to summarize current conservative and interventional multidisciplinary methods and special treatment methods used in chronic pain management and to guide clinicians in cope with pain.
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    The effect of graded motor imagery training on pain, functional performance, motor imagery skills, and kinesiophobia after total knee arthroplasty: randomized controlled trial
    (Korean Pain Soc, 2023) Candiri, Busra; Talu, Burcu; Guner, Emre; Ozen, Metehan
    Background: The aim was to investigate the effect of graded motor imagery (GMI) added to rehabilitation on pain, functional performance, motor imagery ability, and kinesiophobia in individuals with total knee arthroplasty (TKA). Methods: Individuals scheduled for unilateral TKA were randomized to one of two groups: control (traditional rehabilitation, n = 9) and GMI (traditional rehabilitation + GMI, n = 9) groups. The primary outcome measures were the visual analogue scale and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Secondary outcome measures were knee range of motion, muscle strength, the timed up and go test, mental chronometer, Movement Imagery Questionnaire-3, lateralization performance, Central Sensitization Inventory, Pain Catastrophizing Scale, and Tampa Kinesiophobia Scale. Evaluations were made before and 6 weeks after surgery. Results: Activity and resting pain were significantly reduced in the GMI group compared to the control group (P < 0.001 and P = 0.004, respectively). Movement Imagery Questionnaire-3 scores and accuracy of lateralization performance also showed significant improvement (P = 0.037 and P = 0.015, respectively). The Pain Catastrophizing Scale and Tampa Kinesiophobia Scale scores were also significantly decreased in the GMI group compared to the control group (P = 0.039 and P = 0.009, respectively). However, GMI did not differ significantly in WOMAC scores, range of motion, muscle strength, timed up and go test and Central Sensitization Inventory scores compared to the control group (P > 0.05). Conclusions: GMI improved pain, motor imagery ability, pain catastrophizing, and kinesiophobia in the acute period after TKA.
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    Effect of psoriatic arthritis on the strength, proprioception, skill, coordination, and functional condition of the hand
    (Wiley, 2022) Candiri, Busra; Talu, Burcu; Karaoba, Dilan Demirtas; Ozaltin, Gulfem Ezgi; Yolbas, Servet
    Background This study was planned to evaluate the strength, proprioception, skill, coordination, and functional condition of the hand in individuals with psoriatic arthritis and to correlate disease activity with these parameters. Methods Fifty-six individuals (psoriatic arthritis group, n = 36; control group, n = 20) were included in the study. Evaluations were performed of disease activity with Disease Activity Score 28; grip strength with a dynamometer and pinch strength with pinch gauge dynamometers; joint position sensation with a goniometer; finger skills with a mobile application; and coordination and skill of both hands with the Purdue Pegboard test. The Michigan Hand Outcomes Questionnaire (MHQ) was used for hand functional evaluation. Results There was a significant difference between the grip and pinch strength of the psoriatic arthritis group and the control group (P < 0.05). There was no significant difference between the joint position sense measurements and the mobile application scores between the groups (P > 0.05). Purdue Pegboard scores showed a significant difference only in both hands and assembly subsections (P < 0.05). With Disease Activity Score 28, significant correlations were found between grip and pinch strength, mobile application scores, Purdue Pegboard all subsections, and left-hand joint position sense average error amount, and between MHQ and grip and pinch strength. Conclusions This study is the first to show that psoriatic arthritis has a negative effect especially on hand strength; grip strength decreases as disease severity increases and, skill, coordination, and functionality of hand deteriorate.
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    Effects of Sensor Size, Surface Material, and Contact Area on Pressure Measurements in Thin-Film Pressure Sensors
    (Ieee-Inst Electrical Electronics Engineers Inc, 2024) Talu, Burcu; Isik, Ibrahim; Candiri, Busra; Candiri, Yunus; Yapalikan, Remziye Betul
    The existing studies on foot pressure measurement have primarily focused on sensor placement and the number of sensors instead of sensor size and the ground above the sensor; moreover, there is limited research available on the use of different materials in pressure measurement devices manufactured by various companies. This study, therefore, aimed to address these gaps by investigating the measurement accuracy in standard loading conditions, considering different sensor sizes, contact areas, and ground surfaces. Pressure was applied within the sensing diameter of the sensor, and a microcontroller was used to calculate the reciprocal resistance. The results of the study indicated that the coating of sensors with different materials and the shape of the contact surface of the object applying pressure significantly influenced the measurements of the pressure sensors. When comparing the difference according to the sensor sizes, medium-size sensor (18.3 mm); according to surfaces, thin-thick plastazote; according to loading conditions, oval contact areas gave more sensitive values. Future research can further build upon these findings to enhance the design and development of pressure measurement devices, ultimately benefiting scientific research and clinical applications.
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    Investigation of the relationship between femoral anteversion, pelvic inclination and spasticity in children with spastic diplegic cerebral palsy
    (Bayrakol Medical Publisher, 2023) Karaoba, Dilan Demirtas; Candiri, Busra; Talu, Burcu
    Aim: This research was planned to analyze the relationship between femoraloanteversion, pelvic inclination and spasticity in children with spasticodiplegic cerebral palsy. Material and Methods: The study included 33 participants with spasticldiplegic cerebrallpalsy, aged 5-18 years (mean age 13.7 years [SD 3.1 years]; 15 girls, 18 boys), with GrosslMotor Function Classification Score 1 and 2. Femoralianteversion was evaluated with the Craig test. Pelvic inclination angle was measured using a specially designed caliper-like device and a mobile application (rotating sphere clinometer) with a phone placed on the device. Spasticity was evaluated using the Modified Ashworth Scale. The average spasticity values in the lower extremity hip flexor, adductor, internal rotator, knee flexor, plantar flexor and evertor muscles were calculated. Results: A moderate positiveicorrelation was observed between the femoral anteversion angle and pelvic inclination angle (right: r=.373, p<.05; left: r=.412, p<.05) and between femoral anteversion angle and the mean value of lower extremity total spasticity (right: r= .361, p<.05, left: r= .368, p<.05). There was no significant relationship between the pelvic inclination angle and the mean value of lower extremity total spasticity (right: r=.208, p>.05; left: r=.302, p>.05). Discussion: It was observed that an increase in lower extremity spasticity value may cause an increased femoralianteversion angle, while an increase in femoral anteversion may cause an increase in pelvic inclination angle.