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Öğe Does prematurity indicate poor prognosis in the treatment of infant ureteropelvic junction obstruction?(2019) Huseynov, Mirzaman; Emre, Senol; Ozcan, Rahsan; Bakir, Ayten Ceren; Canpolat, Nur; Elicevik, MehmetAim: To evaluate the outcomes of management of ureteropelvic junction obstruction in premature patients by comparing them to a group of non-premature. Material and Methods: We reviewed the medical records of 102 patients with isolated hydronephrosis which were referred from pediatric nephrology outpatient clinic or those who admitted directly to pediatric urology clinic under one year of age between the years of 2005 and 2016. Two groups were set up; premature and term. The gestational age, sex, management for ureteropelvic junction obstruction, complications were recorded. Chi-Square, Fisher’s and Mann-Whitney-U tests were used for statistical analyzes. Results: There were 92 patients in the term group and 10 in the premature group. All patients were operated. Preoperative symptoms such as pyonephrosis, renal calculi, and hypertension were relatively common in the premature group. Preoperative low function, postoperative loss of function, and poor outcome were statistically more common in premature patients. Conclusion: In our limited experience, prematurity is an independent factor associated with UPJO, and it may indicate a poor prognosis. We advocate that this issue should be considered in practice.Öğe Hemolytic uremic syndrome outbreak in Turkey in 2011(Turkish J Pediatrics, 2013) Ekinci, Zelal; Candan, Cengiz; Alpay, Harika; Canpolat, Nur; Akyuz, Sare Gulfem; Gunduz, Zubeyde; Dursun, IsmailThe aim of this retrospective multicenter study was to define the epidemiological and clinical features and prognostic factors of the first diarrhea-related hemolytic uremic syndrome (D+HUS) outbreak in Turkey in 2011. All pediatric nephrology centers in Turkey were asked about D+HUS patients via e-mail. Seventy D+HUS patients (median age: 5.7 years) participated. The seasonal peak was around the 7th, 8th and 9th months with 44 cases, centered in the east Marmara region. No causative agent could be identified. The rate of neurological complications and mortality was 21.4% and 4.2%, respectively. Eculizumab was used in four cases. Two of them had severe neurological complications despite plasma exchange. Elevated polymorphonuclear leukocyte count during hospital admission was the predictor of both severe disease and poor outcome. Duration of prodrome was the predictor of poor outcome (p<0.05). In conclusion, the median age of the affected children was greater than in the previous reports, while clinical features and outcome were similar.Öğe POST-TRANSPLANT LYMPHOPROLIFERATIVE DISEASE IN PEDIATRIC KIDNEY TRANSPLANT RECIPIENTS IN TURKEY(Springer, 2022) Dursun, Ismail; Koyun, Mustafa; Canpolat, Nur; Poyrazoglu, Hakan; Bakkaloglu, Sevcan; Comak, Elif; Gulmez, Ruveyda[Abstract Not Available]Öğe Underserved and Undervalued: The Alarming Collapse in Pediatric Residency Preference in Turkiye(Aves, 2025) Saygili, Seha; Demirbas, Kaan Can; Bagci, Bereket; Kaya, Feray; Sen, Umit; Tabel, Yilmaz; Canpolat, Nur[No abstract available]Öğe Underserved and Undervalued: The Alarming Collapse in Pediatric Residency Preference in Türkiye(AVES, 2025) Saygili, Seha; Can Demirbas, Kaan; Bagci, Bereket; Kaya, Feray; Sen, Umit; Tabel, Yilmaz; Canpolat, Nur[No abstract available]Öğe Vascular access for hemodialysis and catheter-related bloodstream infections: a survey on preventive measures and treatment strategies by the EPDWG and ESPN Dialysis Working Group(Springer, 2026) Bakkaloglu, Sevcan A.; Leventoglu, Emre; Ezgu, Defne; Bayrakci, Umut Selda; Buder, Kathrin; Canpolat, Nur; Cappoli, AndreaThe choice of vascular access (VA) plays a key role in the success of hemodialysis (HD). Despite their widespread use, central venous catheters (CVCs) are associated with higher rates of dysfunction, thrombosis, and catheter-related bloodstream infections (CRBSI). We investigated current practices in pediatric HD across European pediatric nephrology centers, focusing on VA choices, infection control measures, and CRBSI management. An online questionnaire was e-mailed to 119 members of the European Society for Pediatric Nephrology (ESPN) Dialysis Working Group and European Pediatric Dialysis Working Group (EPDWG). Descriptive statistics were used to summarize practices across centers, comparative analyses between centers in countries with Human Development Index (HDI) > 0.90 and < 0.90. Thirty-one centers across Europe participated in the survey. CVCs were the primary VA in 73.1% of the centers. Twenty (66.7%) centers reported malfunction as the most common CVC complication, followed by catheter thrombosis (19.4%) and CRBSI (12.9%). The diagnostic approach for CRBSI varied widely, with 35.4% of centers relying on a single positive catheter culture, while 57.9% did not collect a second culture from the peripheral vein or HD circuit. The most common empirical treatment was glycopeptides combined with third-generation cephalosporins. Nearly all centers used intravenous antibiotics for less than 3 weeks, and over half modified lock solutions with antibiotics following CRBSI diagnosis. Catheter removal practices were inconsistent, even in cases of severe infection. Centers reported a total of 548 HD patients. Exit-site infections and CRBSI were observed in 98 (17.8%) and 155 (28.2%) patients, respectively. CRBSI rates and CRBSI-related catheter replacements were significantly higher in centers from countries with HDI < 0.90 and in centers without a dedicated pediatric HD unit. Conclusion: The suboptimal adherence to current VA recommendations and wide variability in catheter care practices including the prevention, diagnosis, and management of CRBSI highlight the need for standardized pediatric-specific protocols to enhance catheter longevity and improve patient outcomes. What is Known: center dot Central venous catheters are widely used in pediatric hemodialysis but carry a high risk of complications, especially catheter-related bloodstream infections (CRBSI). What is New: center dot This multinational survey reveals significant variability in vascular access selection, CRBSI prevention, diagnosis, and treatment across European pediatric hemodialysis centers, with clear disparities by national HDI levels. center dot The findings highlight the need for standardization of vascular access care and CRBSI management and evidence-based pediatric-specific guidelines.
