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    The hematologic manifestations of pediatric celiac disease at the time of diagnosis and efficiency of gluten-free diet
    (Tubitak Scientific & Technological Research Council Turkey, 2015) Catal, Ferat; Topal, Erdem; Ermistekin, Halime; Yildirim Acar, Nurdan; Sinanoglu, Muhammed Selcuk; Karabiber, Hamza; Selimoglu, Mukadder Ayse
    Background/aim: To determine the hematologic manifestations at the time of diagnosis of celiac disease in children and the effects of a gluten-free diet on hematologic signs upon follow-up. Materials and methods: The records of patients with celiac disease who received a follow up examination at the Pediatric Gastroenterology Clinic between June 2006 and June 2013 were retrospectively examined. Results: Ninety-one patients were included in the study. The mean age at diagnosis was 8.1 +/- 4.21 years and 59 patients (64.8%) were female. Thirty-two patients (35.2%) had hematologic signs at the time of diagnosis. Anemia (24.2%) was the most common hematologic sign, followed by thrombocytosis (16.5%) and leukopenia (4.4%). The tTG IgA titers were screened in 80 of the 91 patients during diagnosis. Follow-up examinations found that remission for anemia (P = 0.017), thrombocytosis (P = 0.039), and decreases in tTG IgA titers (P = 0.034) were more prominent in patients who had followed a strict gluten-free diet. Conclusion: Approximately one-third of the celiac disease patients had hematologic manifestations at the time of diagnosis. Remission in hematologic signs and decrease in tTG IgA titers were more prominent in patients who had adhered to a gluten-free diet.
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    Nasal saline as a placebo in allergic rhinitis
    (Wiley, 2017) Catal, Ferat; Karadag, Ahmet
    [Abstract Not Available]
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    Report of seven children with hepatopulmonary syndrome
    (Aves, 2014) Erge, Duygu; Selimoglu, Mukadder Ayse; Karakurt, Cemsit; Karabiber, Hamza; Elkiran, Ozlem; Catal, Ferat; Koroglu, Reyhan
    Hepatopulmonary syndrome is an important pulmonary vascular complication of liver disease. Its diagnosis is based on the presence of hypoxaemia and the demonstration of intrapulmonary shunting by contrast-enhanced echocardiography or perfusion lung scanning. Awareness of this condition is critical to improve the outcomes of patients with chronic liver disease and/or portal hypertension because hepatopulmonary syndrome receives additional priority on the waiting list for transplantation. A non-invasive measurement of the blood oxygen saturation with pulse oximetry is recommended as a screening tool for this syndrome. The aim of this report was to present clinical and laboratory findings and follow-up of seven paediatric patients who were diagnosed with HPS at our centre.
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    Vitamin and mineral deficiency in children newly diagnosed with celiac disease
    (Tubitak Scientific & Technological Research Council Turkey, 2015) Topal, Erdem; Catal, Ferat; Acar, Nurdan Yildirim; Ermistekin, Halime; Sinanoglu, Muhammed Seluk; Karabiber, Hamza; Selimoglu, Mukadder Ayse
    Background/aim: To establish the frequency of vitamin and mineral deficiency in children newly diagnosed with celiac disease. Materials and methods: The files of patients diagnosed with celiac disease in our Pediatric Gastroenterology Clinic from June 2008 to June 2013 were reviewed retrospectively. Results: A total of 52 pediatric patients diagnosed with celiac disease via serology and duodenal biopsy and who fulfilled the study criteria were enrolled in the study. The mean diagnosis age of the patients was 8.5 +/- 3.9 years and 33 (63.5%) of the patients were female. Vitamin D, vitamin A, vitamin E, zinc, and iron deficiencies were determined in 27 (51.9%), 4 (7.7%), 7 (13.5%), 35 (67.3%), and 18 (34.6%) patients, respectively, at the time of diagnosis. Vitamin D deficiency was observed more frequently in patients with growth retardation at the time of application (P = 0.02). Conclusion: Vitamin D, zinc, and iron deficiency are frequently observed in pediatric patients with celiac disease at the time of diagnosis. Therefore, serum vitamin D, zinc, and iron levels should be checked in all children diagnosed with celiac disease.