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Öğe A 9-year retrospective review of lightning deaths from the Eastern Anatolian Region of Turkey(Humana Press Inc, 2023) Oruc, Mucahit; Dundar, Ahmet Sedat; Samdanci, Emine Turkmen; Celbis, OsmanIn this study, deaths from lightning strikes in Eastern Turkey revealed distinct patterns in lifestyle and physical injury. Farmers, sailors, and those engaged in outdoor sports are all at risk of being struck by lightning. Death from a lightning strike is associated with cardiovascular and central nervous system damage. This study examines cases of autopsies that were performed on bodies that had suffered a lightning strike, including sociodemographic data, burns on the body, injured regions, histopathological findings, and causes of death. This retrospective evaluation included 17 cases. The cases comprised 88.2% males and 11.8% females, with a mean age of 41.5 years. The person's occupation was farmer in 29.4% of the cases and shepherd in 70.6%. Their deaths occurred most frequently in the summer months. Deaths associated with lightning strikes are more frequent in east of Turkey than in other regions, as agriculture and livestock are common sources of income. The majority of the victims among the cases were males working outside because of their occupations. Histopathologically, subarachnoid fresh bleeding was seen in five cases, subpleural fresh bleeding in the lungs in five cases, and interlobular rupture in the lungs in three cases. Deaths associated with lightning strikes have been correlated with a low level of education in this subject. This study is the largest case study of deaths associated with lightning strikes in Turkey.Öğe ASSOCIATION OF BDNF / TRKB AND NGF / TRKA LEVELS IN POSTMORTEM BRAIN WITH MAJOR DEPRESSION AND SUICIDE(Medicinska Naklada, 2021) Erbay, Lale Gonenir; Karlidag, Rifat; Oruc, Mficahit; Cigremis, Yilmaz; Celbis, OsmanBackgroundÖğe Autopsy findings and scene of incident examination in deaths resulting from electrical injury(Taylor & Francis Ltd, 2023) Oruc, Mucahit; Dundar, Ahmet Sedat; Okumus, Hasan; Dengesik, Omer; Altin, Ismail; Samdanci, Emine Turkmen; Celbis, OsmanElectrocution injuries are divided into high (HVI) and low voltage injuries (LVI). The aim of this study was to examine the sociodemographic data of cases where autopsy was performed because of death originating from electric shock, together with the clinical characteristics, scene of incident, electrical entry-exit wound localizations, pathological effects of electric shock on the body, and cause of death. A total of 4210 autopsies were retrospectively reviewed, and 49 had died from electrocution. The mean age of the cases was 29.2 +/- 16.04 years and 87.8% were males and 12.2% were females, 49% of the cases were the result of HVI and 51% the result of LVI. The presence of electrical entry and/or exit wounds were significantly higher in electrocution injuries due to home accidents than work accidents (p < 0.005). There was no statistically significant difference between the deaths caused by the direct effect of electric shock and those who died with LVI and HVI. The deaths of all the cases were accidental in origin, with no suicide or homicide. Deaths due to electrocution due to home or workplace accidents can be determined by examining the crime scene, witness statements, autopsy and histopathological findings.Öğe Autopsy in sudden cardiac deaths(2018) Yener, Zeynep; Celbis, OsmanSudden cardiac death is described as death that occur within the 1st hour of the onset of the symptoms or death within the 24 hours of the onset of symptoms in unwitnessesed deaths. Studies conducted in our country reveal that cardiovascular origined deaths are the most frequent, with a rate of 20% of all deaths. Although sudden deaths in young people are rare, it is important to perform a detailed autopsy and other required procedures. The etiology of the sudden death is hard to determine for the forensic doctors and in 5-1% of all cases no certain cause is determined despite the macroscopic, toxicologic and histopathologic evaluations. European Society of Cardiovascular Pathology also recommends performing molecular autopsy when the certain cardiac cause cannot be determined morphological. This review aims to offer genetical consulting to the family members of the sudden cardiac death cases and clarify the etiology of death via genetical evaluation if the macroscopic, toxicologic and histopathologic examinations fail to explain the cause of the sudden cardiac death especially in children and young adults. The most important problems in our country are the lack of multidisiplinary approach and standardized management methods. In our country molecular autopsy is only considered in rare and selected cases, but if these genetical evaluations were made more applicable and accessible via interdepartmental agreements and the application of new genetical diagnosis methods, it would be possible to develop standardized methods for the case selection of molecular autopsies in the future.Öğe Avrupa birliğine uyum sürecinde yapılan değişiklikler ışığında adli otopsilerin güncel hukuki prosedürü(İnönü Üniversitesi Tıp Fakültesi Dergisi, 2011) Özdemir, Bora; Celbis, Osman; İris, Müfit; Kaya, AtılhanÖz: Türkiye 1999 yılında Avrupa Birliğine (AB) aday ülke olarak kabul edildi. Bu tarihten itibaren mevzuatını AB ile uyumlu hale getirmek için değişiklikler yapmaya başladı. Bu konuda AB adli otopsiler ile ilgili tavsiye kurallarını içeren bildirgesini yayınlandı. Adalet Bakanlığı ve Sağlık Bakanlığı tarafından yeni kanunlar ile uyumlu olarak adli otopsi ile ilgili genelgeler yayınlandı. Adli otopsi yapmak üzere Cumhuriyet Savcılıklarınca bilirkişi olarak davet edilen hekimler yasada belirtilen mazeretleri olmaksızın bu davete uymadıkları takdirde adli görevi ihmal ettikleri gerekçesi ile haklarında dava açılabilir. Bu yazıda AB sürecinde ülkemizde yapılan mevzuat değişiklikleri ışığında adli otopsilerde uyulması gereken hukuki ve tıbbi durumlar gözden geçirildi Başlık (İngilizce): Current legal procedure of forensic autopsy in the light of legislative changes in the european union (eu) ıntegration process Öz (İngilizce): Turkey was accepted as a candidate for the European Union in 1999. Since then changes began to be made to harmonize legislation with the European Union. Advice on the rules of forensic autopsies published in the declaration of the EU. Relevant circulars issued by the Ministry of Justice and the Ministry of Health on forensic autopsy in accordance with new laws. Physicians may be prosecuted on the grounds of criminal neglect of duty if they fail to comply with the public prosecutors invitation as an expert for a forensic autopsy without an excuse. In this article, legal and medical requirements of forensic autopsy cases were reviewed in the light of legislative changes made in our country in the EU integration process.Öğe Comparison of Cardiac Wall Thicknesses and Coronary Artery Obstructions Between Deaths Resulting From Acute Myocardial Infarction and Deaths From Other Causes(Galenos Publ House, 2022) Altin, Ismail; Oruc, Mucahit; Celbis, Osman; Samdanci, Emine T. U. R. K. M. E. N.Objective: The risk factors for myocardial infarction (MI) can be separated into three general categories: non-modifiable factors, modifiable risk factors, and lifestyle. This study aimed to investigate whether or not there was any effect of cardiac wall thickness and coronary artery obstructions on acute MI.Methods: In this retrospective study of histopathological examinations of autopsies, two groups were formed. The first contained 28 cases diagnosed with acute MI and the second 28 cases with no heart pathology and the cause of death was reasons other than heart disease. The subjects in the two groups were similar in age, height, weight, and body mass index. The groups were compared in terms of the left and right ventricular wall thicknesses and the degree of obstruction of the right, left, anterior descending, and circumflex coronary arteries.Results: The mean left ventricular wall thickness was 1.461 +/- 0.2767 cm in the acute MI group and 1.386 +/- 0.2460 cm in the control group, with no statistically significant difference found between the two groups (p=0.289). A statistically significant difference in the degree of obstruction of the coronary arteries was found between the groups.Conclusions: Although the mean cardiac wall thickness was greater in the acute MI cases, no statistically significant difference was found between the two groups.Öğe Cut throat injuries and honor killings: Review of 15 cases in eastern Turkey(Elsevier Sci Ltd, 2013) Ozdemir, Bora; Celbis, Osman; Kaya, AtilhanThroat cuts could be of homicidal, suicidal or accidental origin. In the cases of death from cut throat, suicide can be distinguished from homicide based on the type and location of the wound and crime scene investigation. The purpose of the current study is to attract attention to the instructive findings for origin determination in deaths by cut throat according to the number and characteristics of the wounds and crime scene investigation. We have reviewed the files of autopsies performed between the years of 2000 and 2010, and compared with previously published case reports; all results were summarized in the current study. The results showed that 60% of cases were male, 40% were female, with 27.9 years of average age. The mean number of wounds was calculated to be 34.3 per case for honor homicides, 7.4 per case for other homicides, and 2.0 per case for suicides. Numbers of wounds were approximately 5 times higher in the honor homicides compared to other homicides. If the number of wounds were excessive, possibility of honor killings should be taken into account. When the killer was a parent not in psychosis, hesitation cuts were detected. Additional lesions were present in 46.7% of the cases, and they were assessed as homicide. Presence of vertebral notch and spinal cord cuts, which require a substantial amount of force and pressure via sharp tools, indicates homicide. (C) 2012 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.Öğe Early Stage Pulmonary Embolism Because of Stab Wound Injury Without Vascular Penetration(Aves, 2017) Petekkaya, Semih; Ayaz, Nusret; Dogan, Mustafa; Oruc, Mucahit; Okdemir, Erdem; Celbis, OsmanIntroduction: Pulmonary embolism, occurring as a result of acute obstruction of the pulmonary artery system, may vary from the frequently observed asymptomatic clinical state to sudden death and is a disease with high morbidity and mortality rates. Pulmonary embolism is most commonly observed within 5-7 days of trauma and has been occasionally reported before 4 days. Case Report: A 40-years-old female was admitted to emergency service with a knife wound injury. Her vital and laboratory values were normal. Physical examination revealed a knife wound injury, measuring 2 x 1 cm, on the femoral midline of the left leg. Then, she was discharged. After approximately 6 h, she presented to another emergency service with complaints of chest pain and syncope. During evaluation, she developed cardiopulmonary arrest and died because of pulmonary embolism. Conclusion: This report presents a case of early stage pulmonary embolism that developed because of circulation disruption caused by the effect of pressure as a result of a localized hematoma owing to an indirect effect of a stab wound injury with no vascular penetration injury.Öğe Evaluation of Childhood Traumas, Depressive Symptoms, and Dissociative Experiences in Tinnitus Cases(Galenos Publ House, 2021) Altintas, Mustafa; Sarlak, Deniz; Ozturk, Erdinc; Celbis, OsmanObjective: Tinnitus is described as the perceived sound without any external stimulus and is a common problem, but its mechanism is not fully understood. This study aimed to evaluate childhood traumas and dissociative experiences, which may be predisposing factors in patients with tinnitus.Methods: The study included 90 voluntary patients (45 patients with tinnitus and 45 in the control group) aged older than 18 years who applied to the otorhinolaryngology clinic between November 2018 and February 2019 and were diagnosed with subjective tinnitus. A personal information form together with childhood trauma, hospital anxiety and depression, and dissociative experiences scales were used to assess the patients.Results: Of all participants, 55.60% were males, 28.90% were 20-30 years old, 71.10% were married, 40% were primary school graduates, and 68.90% were employed. In addition, 77.78% of patients did not visit a psychiatrist and 75.56% did not have any chronic diseases. The mean total score of Childhood Trauma Scale for the tinnitus group was 54.37 +/- 10.17, the mean total score of The Hospital Anxiety and Depression Scale for the tinnitus group in the depression subscale was 12.22 +/- 5.41 and in the anxiety subscale was 10.54 +/- 3.5, and Dissociative Experiences was 13.48 +/- 4.68. A positive significant relationship was found between the childhood traumas of the tinnitus cases in their depressive symptoms, and dissociative experiences (p<0.05).Conclusions: The study results found a positive relationship between the childhood traumas and dissociative experiences of tinnitus cases, which can be considered as predisposing factors in patients with tinnitus who should also be investigated for childhood trauma, and the treatment approach should be multidisciplinary.Öğe Evaluation of Incest Cases: 4-Years Retrospective Study(Routledge Journals, Taylor & Francis Ltd, 2020) Celbis, Osman; Altin, Ismail; Ayaz, Nusret; Bork, Turgay; Karatoprak, SerdarIncest is specific type of sexual abuse. The aim of this study was to evaluate the sociodemographic data and examination findings of cases referred to our hospital as forensic court cases of incest, and to measure the effect on mental health disorders of the nature of the sexual abuse. Retrospective examination was made of the records of 40 cases of incest victims. Evaluation was made of the age, gender, incident suffered, the perpetrator, form of abuse, examination findings, and mental status. The cases comprised 36 girls and 4 boys. Without penetration sexual abuse was determined in 25 cases and with penetration sexual abuse in 15 cases. At least one mental health disorder was determined in 20 of the cases of simple sexual abuse and in 11 of the major sexual abuse type cases. The most frequently seen mental health disorder was post-traumatic stress disorder (PTSD) in 21 cases. Mental health disorders were determined in 77.5% of the incest cases in this study, at a greater rate 80% in cases of without penetration sexual abuse than in cases of with penetration sexual abuse 74.33%. Therefore, all cases of incest must be followed up carefully without differentiation of without or with penetration abuse.Öğe Evaluation of organ weights and ventricular thicknesses in electrocution related deaths based on autopsy reports: A biophysical approach(Pakistan Medical Assoc, 2023) Kilinc, Evren; Ozturk, Onur; Oruc, Mucahit; Celbis, OsmanObjective: To evaluate autopsy reports of the deaths due to electrocution in terms of body mass index, body surface area, and organ weights with a biophysical perspective. Method: The retrospective study was conducted in Malatya, Turkiye, and comprised autopsy reports of electrocution cases that were obtained from the local branch of the Council of Forensic Medicine related to the period from 2012 to 2019. Organ weights and ventricular thicknesses were compared in terms of body mass index and body surface area. Electrical marks were also evaluated in detail. Data was analysed using SPSS 18. Results: Of the 45 cases, 36(%) were male and 9(%) were female. The overall mean age was 39 +/- 13 years (range: 20-71 years). There were no significant differences in organ weights and ventricular thicknesses in different body mass index groups (p>0.05). The weights of head and heart were significantly different in relation to body surface area (p<0.05), but no significant difference were found for other organs and ventricular thickness (p>0.05). Conclusion: Comparing the organ weights in electrocution autopsies to normal organ weights may help decide the cause of death. During autopsy, electrical marks should be evaluated by considering the characteristics of the electrical current.Öğe Evaluation of socio-demographic characteristics of people was determined to use synthetic cannabinoids in Malatya and its surrounding cities / districts and LC-MS/MS analysis method(2020) Oruc, Mucahit; Petekkaya, Semih; Soylu, Ozcan; Oner, Bedirhan Sezer; Celbis, Osman; Dinc, Ahmet HakanAim: Synthetic cannabinoids (SC) were initially developed in 1960s to target the cannabinoid receptors in medical therapy. However, in recent years, the developed SC derivatives by processing the plant-based material have been sold on websites under the name of natural drugs.The city of Malatya is located at the eastern part of Turkey and has an important location for the transfer and marketing of narcotic substances. In our study, presentation of the socio-demographic characteristics of the cases, the SC was determined in whose blood samples in the analyses, living in Malatya and the surrounding cities-districts were aimed.Materials and Methods: In the scope of study, 275 cases whose blood samples was sent to the Chemistry Department in Forensic Medicine Institute at Malatya Group Presidency in 2016 and were detected as SC-positive by the chemical analysis were investigated.Results: Out of 275 cases, 97.8% were male, 2.2% were female. Median age was 24, 66.5% (n=180) of them were primary school, 18% (n=51) were high school graduate and 0.7% (n=2) were university graduate. The educational status of 27 cases could not be obtained.Conclusion: SC derivatives are marketed with slogan of “the natural ones are harmless”, and their use among the young people is rapidly becoming widespread. In our study, it was determined that the SC users are in the young age group and have low educational status. In order to decrease the number of users, awareness meetings regarding the harmful effects of SC must be organized in the educational institutions.Öğe Examination of the sexually assaulted child(Turkish Pediatrics Assoc, 2011) Celbis, Osman; Ozdemir, Born; Kaya, AtilhanSexual assault on the child has been accepted as one of greatest crimes in the World. In case of a sexually attacked child appliying to the health center the prior management must be protecting the physical and psychological health of the child. Clinical and other examinations have to be performed immediately and the medicolegal report should also be prepared as soon as possible. It cannot be forgotten that the medicolegal report substantially supports the subject being sexually assaulted. Finally it is the proof that reflects the intensity of the event and it's wickedness. From this perspective, the medicolegal report has to cover all findings related to events. In this paper, the rules of the sexually assaulted child examination, the appropriate environment, for the examination the qualification of examiners and the obligatory procedures performed by physicians before during and after the examination are stated. (Turk Arch Ped 2011; 46: 104-10)Öğe An examination of the sociodemographic and psychiatric characteristics of children who have suffered penetrative and non-penetrative sexual abuse in Malatya, Eastern Turkey(Wiley, 2022) Dundar, Ahmet Sedat; Oruc, Mucahit; Altin, Ismail; Donmez, Yunus Emre; Celbis, OsmanPenetrative and nonpenetrative sexual abuse can cause short- and long-term psychiatric problems in victims. This study aimed to examine the sociodemographic characteristics and psychiatric diseases of children in Malatya, eastern Turkey, according to whether the abuse was penetrative or nonpenetrative. A retrospective examination was conducted on the records of 115 cases of sexual abuse that had been referred to judicial authorities from January 1, 2012-July 30, 2019. The subjects were evaluated by a committee formed of 5-7 separate specialized department faculty members. It was determined that 51.3% (n = 59) of the cases had suffered nonpenetrative sexual abuse, and 48.7% (n = 56) had suffered penetrative sexual abuse. The majority of the perpetrators were known to the child from their close environment. A psychiatric diagnosis was made by the committee in 20.3% (n = 12) of the nonpenetrative cases and in 42.9% (n = 24) of the penetrative cases. There was a significant difference between penetrative and nonpenetrative sexual abuse in terms of psychiatric diagnoses. Of the cases of penetrative sexual abuse, 87.5% (n = 14) had attempted suicide. As a result, early diagnosis of sexual abuse, which has devastating effects on mental health in the early and late periods before it penetrates, can reduce the devastating effects on the child. For this reason, it is crucial for doctors, psychologists, social workers, and teachers who work with children to be informed about this issue.Öğe An experimental rat model of electric shock injury with isolated electric shock and water conduction: the histopathological changes on the skin and internal organs and the effect on biochemical parameters(Springer, 2023) Dundar, Ahmet Sedat; Oruc, Mucahit; Celbis, Osman; Samdanci, Emine Turkmen; Akatli, Ayse Nur; Okumus, Hasan; Taskapan, CagatayIt is difficult to determine the cause of death in electric shock injuries when no trace can be determined on the skin, and this is accepted as a reason for negative autopsy. We aimed to determine useful parameters in the definition of the cause of deaths associated with electric shock and particularly those formed with water conduction. This study used a total of 42 rats, applied with fatal electric shock formed of isolated electric shock at 220 V and with water conduction. The serum NT-ProBNP and H-FABP levels were examined together with histopathological changes in the brain, cerebellum, brainstem, heart, liver and skin and the Bax, caspase-3 and HSP-60 antibody status in these tissues. A statistically significant difference was determined between the groups in respect of the serum H-FABP values and the immunohistochemical staining of the samples taken from the organs. In conclusion, this study is the first in literature with an experimental model of electric shock with water conduction. Using immunohistochemical and biochemical markers in deaths associated with isolated electric shock and electric shock with water conduction, the results of this study can contribute to the clarification of one of the reasons for negative autopsy in forensic medicine.Öğe Forearm Bones and Sexual Variation in Turkish Population(Lippincott Williams & Wilkins, 2011) Uzun, Ibrahim; Iscan, Mehmet Yasar; Celbis, OsmanForensic anthropologists are aware that there are considerable differences between human populations and therefore develop study models for each skeletal population. The purpose of this study was to analyze forearm bones obtained from forensic settings in Turkey. The sample consists of 42 males and 38 females with an average age of 40 and 36 years, respectively. Numerous measurements were taken from the radius and ulna including lengths (in millimeters), midshaft diameters, and epiphyseal breadths (0.01 mm). Individuals with any anomaly and pathology were not included in the investigation. A stepwise analysis, when applied to individual bones, selected only length and midshaft transverse dimension in the radius and length only in the ulna. When the length was excluded from the statistic, head diameter and distal breadth of the radius and distal minimum head and midshaft anteroposterior diameters of the ulna provided the best predicting functions. Classification results were 92% for the radius and 91% for the ulna. For the incomplete bones, the accuracy rates were about 92% and 83%, respectively. In conclusion, a sex determination was made, in different rates of accuracy, in the human skeleton. Correct assessment can vary among populations. Dimorphism in our region forearm bones is greater than American whites. This supported the hypothesis that human variation is diverse, and population difference should be taken into account when osteometric standards are applied to others. Further studies are needed to understand why the forearm is more dimorphic in Turks.Öğe Foreigners Dying in Istanbul(Wiley, 2009) Uzun, Ibrahim; Celbis, Osman; Baydar, Cetin Lutfi; Alkan, Nevzat; Arslan, Murat NihatThe study included 411 deaths selected from 14,647 medicolegal deaths autopsied in the Morgue Department of Forensic Medicine Institute Directorate, affiliated with the Ministry of Justice, between 1998 and 2002. Data were collected from court documents, coroner's investigation reports, and autopsy reports. The parameters of age, gender, nationality and origin, cause and place of death in foreigners dying in Istanbul were evaluated in the study. Out of 14,647 medicolegal deaths, 3.5% were foreigners from 34 different nationalities. The nationality with the highest rate of foreigner deaths (34%) was Romanian. Out of 411 deaths, 74.3% were male and 25.7% were female. Of all cases, 64.4% were tourists visiting Istanbul and 35.6% had a job in Istanbul. Of 146 foreigners employed in Istanbul, 94.5% did not have a work permit, while only 5.5% had a work permit.Öğe Histopathological evaluation of autopsy cases with isolated pulmonary fat embolism (IPFE): is cardiopulmonary resuscitation a main cause of death in IPFE?(Dove Medical Press Ltd, 2019) Samdanci, Emine Turkmen; Celik, Muhammet Reha; Pehlivan, Sultan; Celbis, Osman; Turkkan, Dilhan; Kara, Dogus Ozdemir; Pamukcu, EsraBackground: Fat embolism (FE) may develop following many traumatic and atraumatic clinical conditions; however, fewer data exist regarding the occurrence of isolated pulmonary FE (IPFE). Cardiopulmonary resuscitation (CPR) is an emergency procedure for maintaining blood circulation and oxygenation during cardiac arrest. In this study, we aimed to evaluate the association of CPR with IPFE in autopsy cases. Methods: A total 402 cases among 4,118 autopsies were diagnosed with IPFE, and the medical background of these cases was retrospectively evaluated. Diagnosis of FE and FE grading were performed with histopathological examinations of postmortem tissue samples, and injury-severity scores of traumatic cases were assessed. Data of traumatic and atraumatic cases were statistically compared. Results: Of the IPFE cases, 298 (741%) were male and 104 (25.9%) female, with overall mean age 53.7 (2-99) years. Causes of death of studied subjects were traumatic for 302 (75.1%) and atraumatic reasons for 100 (24.9%) cases. CPR was performed for 277 cases of which 177 (63.9%) were traumatic and 100 (36.1%) were non-traumatic. In comparison to traumatic cases, significantly higher CPR frequency was determined in atraumatic IPFE (P=0.001). High grade FE in the traumatic cases, and mild-moderate grade of FE in the nontraumatic cases were found statistically significant (P=0.001). Conclusion: This study indicates that CPR may be one of the leading factors in the development of IPFE in atraumatic conditions, and this procedure was related to mild-moderate IPFE manifestations. Regardless of whether conditions were traumatic or atraumatic, in patients who survive following CPR for manifest ventilation/perfusion problems, it should be remembered that IPFE may have developed due to CPR.Öğe Investigation of Lead Mobilization from the Buckshot Residues to the Critical Organs(Humana Press Inc, 2011) Celbis, Osman; Karakoc, Yunus; Ozdemir, Bora; Gulyasar, Tevfik; Cakina, SuatLead exposure causes neurotoxicity, reproductive system dysfunction, renal failure, and blood and endocrine system disorders in human and experimental animals. In this study, we investigated lead mobilization from gunshot fragments to the critical organs (brain, heart, liver, and kidney) and its interaction with essential trace elements on experimental rat model. Thirty-five rats were randomly divided in five groups. The first group was a control and the others were subjected to buckshot implantation in their skeletal muscles (second and third groups) and abdomen (fourth and fifth groups). The control group and the second and fourth groups were sacrificed 1 month after the onset of experiment while the third and fifth groups were followed after 2 months. Blood lead levels were significantly elevated in both 2 month-followed groups and 1 month-followed intraabdominal group. There were significant increases in brain lead levels of both 2 month-followed groups. For the 1 month-followed groups, kidney lead levels were also significantly higher than those of controls. Results show that lead mobilizes from the buckshot residues in distance tissues to the critical organs and interacts with iron, copper, and zinc even though blood lead level sometimes remains unchanged. Our findings are crucial in revealing lead accumulation in critical organs of subjects carrying any gunshot fragments. These subjects and physicians should be in alert for emergence of lead-induced manifestations.Öğe Oxidative stress status of individuals involved in traffic accidents(Tubitak Scientific & Technological Research Council Turkey, 2012) Ozdemir, Bora; Kaya, Atilhan; Sogut, Ozgur; Kaya, Halil; Gokdemir, Mehmet Tahir; Celbis, OsmanAim: To investigate the role of the oxidative stress status of drivers involved in traffic accidents as a risk factor. Materials and methods: Twenty-six drivers and 28 passengers involved in traffic accidents and 31 healthy control drivers and 30 healthy control pedestrians were enrolled in the present study. The total antioxidant status (TAS) and total oxidant status (TOS) were measured in blood samples. Results: The mean value of the TO S level in drivers involved in traffic accidents was significantly higher than that of the control pedestrians (P <= 0.05). The mean value of the TAS level in passengers involved in traffic accidents was significantly lower than that of the control drivers and pedestrians (P <= 0.001 and P <= 0.01, respectively). Conclusion: This is the first study assessing the oxidative markers of individuals involved in a traffic accident compared with a control group. The results reveal that involvement in a traffic accident has an effect on oxidative markers. However, further studies are required in order to use the oxidative stress status of drivers involved in traffic accidents as a marker for estimating the accident risk.
