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Öğe Follicular fluid adenosine deamines (ADA), superoxide dismutase and nitric oxide levels in GnRH agonist and antagonist cycles(Oxford Univ Press, 2012) Celik, E.; Celik, O.; Kumbak, B.; Yilmaz, E.; Turkcuoglu, I.; Simsek, Y.; Karaer, A.[Abstract Not Available]Öğe Glutathione, malondialdehyde and nitric oxide levels in endometrium of patients with unexplained infertility during the implantation window(Oxford Univ Press, 2012) Karaer, A.; Celik, O.; Karabulut, A. Bay; Celik, E.; Kiran, T. R.; Simsek, O. Y.; Yilmaz, E.[Abstract Not Available]Öğe Lipid features of polycystic ovary syndrome under different diagnostic criteria(Oxford Univ Press, 2013) Celik, E.; Turkcuoglu, I.; Ata, B.; Karaer, A.; Kirici, P.; Berker, B.[Abstract Not Available]Öğe Plasma urocortin levels in women undergoing long agonist and antagonist protocols for IVF(Oxford Univ Press, 2011) Celik, N.; Celik, O.; Aktan, E.; Ozerol, E.; Celik, E.; Bozkurt, K.; Paran, H.[Abstract Not Available]Öğe Prokineticin 1 leukemia inhibitory factor and Dickkopf 1 mRNA expression in the endometrium of women with unexplained infertility and idiopathic recurrent pregnancy loss(Oxford Univ Press, 2014) Karaer, A.; Cigremis, Y.; Celik, E.; Gonullu, R.[Abstract Not Available]Öğe Role of endometrial concentrations of heavy metals (cadmium, lead, mercury and arsenic) in the aetiology of unexplained infertility(Elsevier, 2014) Tanrikut, E.; Karaer, A.; Celik, O.; Celik, E.; Otlu, B.; Yilmaz, E.; Ozgul, O.Objective: To determine the role of endometrial concentrations of heavy metals (cadmium, lead, mercury and arsenic) in the aetiology of unexplained infertility. Study design: Thirty-three women with unexplained infertility and 32 fertile women were recruited. Endometrial biopsies were collected during the putative window of implantation (cycle days 20-24). The concentrations of cadmium, lead, mercury and arsenic were measured in endometrial biopsy specimens using atomic absorption spectrometry. Results: Cadmium was detected in 91% (30/33) of women with unexplained infertility, compared with 34% (11/32) of fertile women. The median endometrial cadmium concentration was 19.58 (interquartile range 1.46-30.23) mu g/l in women with unexplained infertility, compared with 0.00 (interquartile range 0.00-0.40) mu g/l in fertile women. Lead was detected in 15% (5/33) of women with unexplained infertility and 3% (1/32) of fertile women. Mercury and arsenic were not detected in any endometrial samples from either group. Conclusion: A significant difference in endometrial cadmium concentration was found between women with unexplained infertility and fertile women. This suggests that cadmium may be a contributing factor in the aetiology of unexplained infertility. (C) 2014 Elsevier Ireland Ltd. All rights reserved.Öğe Spontaneous resolution of fetal dural sinus thrombosis following term delivery of a live infant(Wiley-Blackwell, 2012) Simsek, Y.; Oztanir, N.; Sigirci, A.; Celik, E.; Yilmaz, E.; Celik, O.; Onal, C.[Abstract Not Available]Öğe XPD and XRCC1 gene polymorphism in patients with normal and abnormal cervical cytology by pap smear(Verduci Publisher, 2012) Yilmaz, E.; Celik, O.; Celik, E.; Turkcuoglu, I.; Simsek, Y.; Karaer, A.; Otlu, B.AIM: The purpose of the present study was to identify the role of abnormalities in DNA repair pathways by measuring the XPD and XRCC1 gene polymorphisms. MATERIALS AND METHODS: Thirty-five patients with abnormal cervical cytology (study group) and 10 women with normal cytology (control group) were included in the study. The polymorphisms of XRCC1 Arg194Trp, XRCC1 Arg399Gln and XPD Lys751Gln genes were investigated from the blood samples. RESULTS: There was no statistically significant difference in allele frequencies of XPD gene among the groups (p = 0.097), while XRCC1R399Q gene polymorphism was strikingly more frequent in the study group than that of control cases (p = 0.029). The prevalence of XRCC1R194W gene polymorphism on the other hand, was similar between the groups (p = 0.579). CONCLUSIONS: Patients with abnormal and normal cervical cytology have similar XPD gene polymorphism. However, the frequency of gene polymorphism in XRCC1 Arg 399 Gln codon was significantly higher in abnormal cervical cytology group.
