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    Comparative investigation of the effects of different materials used with a titanium barrier on new bone formation
    (Wiley, 2013) Ezirganli, Seref; Polat, Serkan; Baris, Emre; Tatar, Ilkan; Celik, Hakan Hamdi
    Objectives In this study, we aimed to study the effects on new bone formation of autogenous blood, deproteinized bovine bone graft (DBBG), and biphasic calcium phosphate (BCP) bioceramic graft materials placed under titanium barriers. Material and methods Twenty-four adult male New Zealand white rabbits were used in this study. Two titanium barriers were fixed on each rabbit's calvarium. The study included four groups, one of which was a control group. The experiment groups, autogenous blood, DBBG (Bio-Oss (R); Geistlich Biomaterials, Wolhusen, Switzerland) and BCP (4BoneTM; Biomatlante, Vigneux de Bretagne, France) were placed under titanium barriers; in the control group, no materials were used. Half of the animals were sacrificed after 1month, and the rest were sacrificed after 3months. After this, micro-computerized tomography images were taken, and a histomorphometric evaluation was carried out. Results The amounts of new bone formation were found to be higher at the third month than at the first month. The differences between the groups were examined with both a micro-computerized tomography and histomorphometric analysis, and no statistical significance was noted in the first month. In contrast, the increase in the amount of new bone formation at the third month was found to be statistically significant only between the DBBG and control groups (P<0.05). Conclusion Autogenous blood with titanium barriers in guided bone regeneration seems to be as successful as DBBG and BCP bioceramic graft material.
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    Micro-CT Detection and Characterization of Porosity in Luting Cements
    (Wiley-Blackwell, 2015) Malkoc, Meral Arslan; Sevimay, Mujde; Tatar, Ilkan; Celik, Hakan Hamdi
    Purpose: To evaluate porosity volume and localization in luting cements under fixed dental prostheses after cementation using micro-computed tomography (CT). Materials and Methods: Seventy-seven sound molars were circumferentially prepared to receive all-ceramic crowns, and IPS e.max ceramic copings were fabricated according to the manufacturer's instructions. For this study, different dental luting cements were used: eight resin-based cements (Variolink II, RelyX ARC, Clearfil Esthetic, BisCem, RelyX U100, Panavia EX, Super Bond C&B, and Multilink Automix), one resin-modified glass ionomer (Ketac Cem Plus), one glass ionomer (Ketac Cem), and one polycarboxylate (Durelon). Specimens were scanned with a micro-CT (SkyScan) for detection and comparison of the cements' porosities. Statistical analyses were performed using Kruskal-Wallis one-way ANOVA and Bonferroni's adjusted Mann-Whitney U tests. Results: Multilink Automix (Volume = 0.11 +/- 0.08 mm(3); Surface Area = 1.63 +/- 1.31 mm(2)), Ketac Cem Plus (Volume = 0.22 +/- 0.21 mm(3); Surface Area = 4.32 +/- 3.71mm(2)), and Variolink II (Volume= 0.34 +/- 0.38mm(3); Surface Area= 6.47 +/- 5.10 mm(2)) contained less porosity (p < 0.001) than all other cements. All other cements were not significantly different from one another (p > 0.05); however, the volume and surface area of the porosity found in the other tested luting cements were significantly greater than those of the Multilink Automix, Ketac Cem Plus, and Variolink II (p < 0.001), all of which demonstrated no significant differences (p > 0.05). Conclusion: The liquid and powder forms prepared by manually mixing the cements were found to cause greater porosity.