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    1-Benzyl-3-[(trimethylsilyl)methyl]benzimidazolium chloride monohydrate
    (Wiley-Blackwell, 2010) Akkurt, Mehmet; Celik, Ismail; Kucukbay, Hasan; Sireci, Nihat; Buyukgungor, Orhan
    The title compound, C(18)H(23)N(2)Si(+)center dot Cl(-)center dot H(2)O, was synthesized from 1-[(trimethylsilyl)methyl]benzimidazole and benzyl chloride in dimethylformamide. The benzimidazole ring system is approximately planar, with a maximum deviation of 0.022 (2) angstrom, and makes an angle of 74.80 (12)degrees with the phenyl ring. The crystal packing is stabilized by O-H center dot center dot center dot Cl, C-H center dot center dot center dot Cl, C-H center dot center dot center dot O and C-H center dot center dot center dot pi interactions between symmetry-related molecules together with pi-pi stacking interactions between the imidazolium and benzene rings [centroid-centroid distance = 3.5690 (15) angstrom] and between the benzene rings [centroid-centroid distance = 3.7223 (14) angstrom].
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    Cutaneous melanoma in Turkey: analysis of 1157 patients in the Melanoma Turkish Study
    (Imprimatur Publications, 2015) Abali, Huseyin; Celik, Ismail; Karaca, Burcak; Turna, Hande; Saglam, Esra Kaytan; Akman, Tuelay; Oztop, Ilhan
    Purpose: To develop a large Turkish National Melanoma registry in order to define demographic and clinicopathologic characteristics of patients with melanoma. Methods: The data was collected from 1635 patients with melanoma through a web-based registry system in 22 centers. Herein we present the results of 1157 patients with cutaneous melanoma. Results: The patient median age was 56.4 years and 646 (55.8%) were males. The commonest subtype was superficial spreading type (357, 30.9%). The commonest primary site was the lower extremities (N=353, 30.5%). The most common Breslow thickness was 1-2 mm (361 patients, 43.5%). Only 104 (12.5%) patients had a thickness <1mm. Among 694 patients with available data, 136 (19.6%) presented with stage 4 disease while the most frequent stage was stage 3, encountered in 393 (56.6% patients). Conclusion: Our melanoma registry is the largest in our country providing a snapshot view of cutaneous melanoma and its care. Our patients presented with more advanced stages and they had worse prognosis compared to SEER database.