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    Incidence of intestinal parasites among primary school children in Malatya
    (2006) Celik T.; Daldal N.; Karaman U.; Aycan O.M.; Atambay M.
    The aim of this study was to determine the incidence of intestinal parasites among primary school children in the central region of Malatya and to educate the children about parasitic diseases. During the study, cellophane tape preparations and stool samples that had been prepared using direct mounting methods were examined. In addition the students were informed about intestinal parasites. Parasitic infection was observed in 415 (22.5%) out of 1838 students and the highest rate of 10.6% was that of Enterobius vermicularis. The rates of Giardia intestinalis, Entamoeba coli, Blastocystis hominis, Taenia sp., Hymenolepis nana, Trichomonas hominis, Ascaris lumbricoides and Iodamoeba butschlii were found to be 8.5%, 1.9%, 1.4%, 0.3%, 0.1%, 0.1%, 0.05%, and 0.05%, respectively. Thus, intestinal parasites are important among primary school children in Malatya and it seems that there is a relationship between socioeconomic conditions and the rate of intestinal parasites.
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    Plasminogen activator inhibitor -1 levels in patients with primary varicose vein
    (2012) Erguzel N.; Yetkin E.; Erdem G.; Erdil N.; Yetkin G.; Heper G.; Celik T.
    Aim. Plasmin is involved in extracellular matrix remodeling by activating some matrix metallo-proteinases and degrading extracellular matrix; therefore component of fibrinolytic system such as tissue plasminogen activator and plasminogen activators inhibitors (PAI-1) might have a role in the pathogenesis of vascular remodeling. In our study we aimed to investigate the levels of PAI-1 levels in patients with primary varicose veins (VV) and in their age and gender matched control group. Methods. Forty-one consecutive patients with peripheral varicose veins and 37 healthy age and gender-matched control subjects were included in the study from the outpatient cardiology and cardiovascular surgery clinic. Study population consisted of 41 consecutive patients who met the inclusion criteria and diagnosed as having class II primary VV according to CEAP classification. Routine biochemical and hematological analysis were performed in all patients and control subjects. Results. Plasma levels of PAI-1 were found to be lower in patients than those in control subjects (5.19±2.2 ng/mL vs. 6.47±2.6 ng/mL, P=0.025). Logistic regression analysis revealed that only the plasma levels of PAI-1 were found to be independently but inversely associated with the presence of primary VVs (Odds ratio: 0.80 CI: 0.64-0.99, P=0.04). Conclusion. We have shown that PAI-1 levels are significantly decreased in patients with pVVs and it has an independent association with the presence of pWs. However, its exact relation and role via matrix metlalloproteinases on the pathogenesis of the disease remains to be elucidated in further studies.
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    ST elevation during treadmill exercise test in a young patient with slow coronary flow: A case report and review of literature
    (2006) Celik T.; Iyisoy A.; Kursaklioglu H.; Yuksel C.; Turhan H.; Isik E.
    The coronary slow flow phenomenon is an angiographic curiosity characterized by delayed distal vessel opacification provided that the presence of significant epicardial coronary disease is excluded. Slow flow phenomenon in epicardial coronary arteries is not infrequent finding during routine coronary angiography. However, the clinical features of patients with slow flow phenomenon have not been extensively studied. ST elevation in leads without Q waves during exercise testing has not been previously reported in patients with slow flow phenomenon. In the current case, we report a 29-year-old man with angiographically normal coronary arteries associated with slow coronary flow in the absence of any significant obstructive coronary artery disease and no evidence of epicardial coronary artery spasm in whom ST segment elevation in leads I and aVL was observed at maximal exercise of treadmill test. © 2006 Elsevier Ireland Ltd. All rights reserved.