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Öğe Comparison of lower extremity anthropometric measurements of healthy and pes planus patients in early adolescence(2020) Solgun, Selma; Cetin, Aymelek; Ozbag, Davut; Ceylan, Mehmet Fethi; Tanriverdi, Cem GurkanAim: Pes Planus (PP) was defined as the decrease or loss of length of arcus longitudinalis medialis (MLA). The aim of the present study is to find out whether PP causes any anthropometric changes in individuals and to determine the relationship between PP and foot type.Materials and Methods: A total of 100 individuals, 50 PP patients (25 female and 25 male) and 50 healthy individuals (25 female and 25 male), between the ages of 11 and 14 were included. Circumference of waist, hip, thigh, leg, bimalleolar and foot; tarsal and MLA height; bimalleolar and foot breadth were measured. Leg index, foot index and foot types were calculated with various anthropometric rates. Results: Significant differences were found in female circumference measurements of the waist, hip, both thighs and right foot bimalleolar (P .05). Significant differences were found in right and left foot bimalleolar circumferences measurements and leg indexes in men (P .05). Significant differences were found in both genders in right and left foot MLA and tarsal heights (P .05).Conclusion: It was found that PP affects not only the foot anthropometric measurements but also the hip, thigh and leg measurements. Early treatment for PP can provide irreversible lower extremity problems that cause lower quality of life.Öğe Distribution of the sciatic nerve and its branches in cadavers(2019) Cetin, AymelekAim: The aim of this study was to determine whether the sciatic nerve and cutaneous branches originating from the nerve show any difference from the pattern described in textbooks. Material and Methods: For this purpose, six cadavers four males and two females were provided School of Medicine of Firat University. Results: The cadavers were dissected starting from formation of the sacral plexus and the sciatic nerve. Their portions in gluteal region and extensions in thigh area were examined. The diversion points of the common peroneal (fibular) nerve and the tibial nerve were determined and their lengths and thicknesses were measured. Diversion point of the sural nerve, which is a cutaneal nerve, was determined. The common peroneal nerve and the tibial nerve were followed up to their terminals. In this study, it is observed that the sciatic nerve was formed of the spinal nerves originating from the L 4-5 – S 1-2. The sural nerve formations were various in cadavers. Conclusion: This study demonstrated that the sciatic nerve formed from the spinal nerves originating from the L 4-5 – S 1-2. The sural nerve formations were various in cadavers and it was understood that a certain formation of the sural nerve could not be described.Öğe Effects of ciprofloxacin and quercetin on fetal brain development: a biochemical and histopathological study(Taylor & Francis Ltd, 2019) Dogan, Zumrut; Cetin, Aymelek; Elibol, Ebru; Vardi, Nigar; Turkoz, YusufPurpose: Teratogens cause birth defects and malformations while human development is being completed. In pregnancy, urinary tract infection (UTI) is a common health problem caused by bacteria. The fluoroquinolones such as ciprofloxacin, levofloxacin, moxifloxacin, and gemifloxacin can treat various types of bacterial infections successfully. The aim of this study is to determine whether the use of ciprofloxacin during pregnancy causes oxidative stress on brain tissues of the fetus, and whether quercetin contributes to prevent this damage if stress has already occurred.Materials and methods: In our study, 22 young female Wistar albino rats weighing 250g were used. Rats were mated overnight in separate plastic cages. Female rats were regarded as pregnant when a vaginal plug was observed, and these were divided into four groups of control, ciprofloxacin, quercetin, and cipro+quercetin. Two daily i.p. 20mg/kg doses of ciprofloxacin were administered to ciprofloxacin group between 7 and 17 d of pregnancy. Throughout the study, daily (20 d) 20mg/kg quercetin was dissolved in corn oil and administered to the quercetin group by oral gavage. Rats were fed ad libitum throughout the study. Fetuses were taken by C-section on the 20th day of pregnancy. Thereafter, the brain tissues were subjected to histological assessments and biochemical analyzes.Results: The experimental groups were compared with the control group; ciprofloxacin affected fetal development, especially caused damage to neurons in brain tissue and cause hemorrhagic defects. And also, it was determined that many parameters were affected such as antioxidant parameters, enzyme levels and levels of malondialdehyde (MDA) (a marker of lipid peroxidation). Quercetin is a member of flavonoid with strong antioxidant properties, and our results indicate that the use of ciprofloxacin in pregnancy can result damage to fetal brain tissue.Conclusions: Unlike these results when some parameters are evaluated it is understood that this harmful effects suppressed by quercetin.Öğe The evaluation of the effect of vaginal delivery and aging on anal sphincter anatomy and function(Elsevier Masson, Corporation Office, 2018) Cay, Mahmut; Cetin, Aymelek; Ates, Mustafa; Koleli, Isil; Senol, Deniz; Kose, Evren; Ozgor, DincerObjective. - This study was conducted to evaluate the effect of vaginal delivery and aging on anal sphincter anatomy and function. Method. - Asymptomatic thirty women were included in this prospective study. Group 1 included 10 women (age range: 18-50) who had never been pregnant. Group 2 included 10 women (age range: 18-50) who had vaginal delivery. Group 3 included 10 women over 50 who had vaginal delivery. Results. - There was no statistically significant difference between the three groups in terms of resting and squeeze pressures. It was found that sphincter thickness showed statistically significant difference between the group 1 and group 3, and also group 2 and group 3. There was not statistically significant difference between the group 1 and group 2 in terms of sphincter thickness. There was a positive correlation between the age and sphincter thickness in all groups. In terms of sphincter thickness and pressure findings there was a positive correlation between the squeeze pressure and external anal sphincter thickness only in group 3. Conclusion. - The vaginal delivery did not have a negative influence on the structure and function of the anal sphincter in asymptomatic women. However, it was found that anal sphincter thickness changed strongly in a positive manner with aging. (C) 2018 Elsevier Masson SAS. All rights reserved.Öğe The evaluation of the effect of vaginal delivery and aging on anal sphincter anatomy and function (vol 47, pg 309, 2018)(Elsevier Masson, Corp Off, 2020) Cay, Mahmut; Cetin, Aymelek; Ates, Mustafa; Koleli, Isil; Senol, Deniz; Kose, Evren; Ozgor, Dincer[Abstract Not Available]Öğe The evaluation of the effect of vaginal delivery and aging on anal sphincteranatomy and function(Elsevıer masson, corporatıon offıce, 65 camılle desmoulıns cs50083 ıssy-les-moulıneaux, 92442 parıs, france, 2018) Cay, Mahmut; Cetin, Aymelek; Ates, Mustafa; Koleli, Isil; Senol, Deniz; Kose, Evren; Ozgor, Dincer; Simsek, Arife; Ozbag, DavutObjective. - This study was conducted to evaluate the effect of vaginal delivery and aging on anal sphincter anatomy and function. Method. - Asymptomatic thirty women were included in this prospective study. Group 1 included 10 women (age range: 18-50) who had never been pregnant. Group 2 included 10 women (age range: 18-50) who had vaginal delivery. Group 3 included 10 women over 50 who had vaginal delivery. Results. - There was no statistically significant difference between the three groups in terms of resting and squeeze pressures. It was found that sphincter thickness showed statistically significant difference between the group 1 and group 3, and also group 2 and group 3. There was not statistically significant difference between the group 1 and group 2 in terms of sphincter thickness. There was a positive correlation between the age and sphincter thickness in all groups. In terms of sphincter thickness and pressure findings there was a positive correlation between the squeeze pressure and external anal sphincter thickness only in group 3. Conclusion. - The vaginal delivery did not have a negative influence on the structure and function of the anal sphincter in asymptomatic women. However, it was found that anal sphincter thickness changed strongly in a positive manner with aging. (C) 2018 Elsevier Masson SAS. All rights reserved.Öğe Evaluation of Willis Polygon Morphometry with Cranial Tomographic Angiography(Turkish Neurosurgical Soc, 2023) Ciftci, Rukiye; Cetin, Aymelek; Ulubaba, Hilal Er; Senol, Deniz; Cinarli, Fahri Safa; Ozbag, DavutAIM: To examine the morphometric properties of the vessels forming the Willis polygon (WP) in patients with type 2 diabetes mellitus (T2DM) and hypertension (HT) and compare them with healthy individuals.MATERIAL and METHODS: Cranial Tomography Angiography (CTA) of 168 individuals were analyzed retrospectively. The individuals included in the study were divided into four groups according to the diagnosis. Group 1 included 40 individuals who were diagnosed with HT, Group 2 included 43 individuals who were diagnosed with DM, Group 3 included 42 individuals who were diagnosed with DM and HT, and Group 4 was the control group and included 43 individuals. The diameter and length measurements of the vesselsRESULTS: According to the results of the Kruskal Wallis H test, in female patients statistically significant differences were detected in the diameter measurements of the right and left A1 segment of the ACA, the diameter measurement of the left A2 segment, the diameter measurements of the right and left P1 and P2 segments of the ACP, the diameter measurements of the right and left AComP. (p<0.05), in male patients statistically significant differences were found in the diameter of the right A1 segment of the ACA, the diameter and segment length measurements of the right and left P1 segments of the ACP, of the right and left P2 diameter measurements, and segment length measurements of the left AComP (p<0.05).CONCLUSION: We also found that the vessel diameters were similar in the HT, DM and HT+DM groups, and smaller than the control group. In addition, we think that knowing WP morphometric measurements will both guide the radio-anatomical evaluations to be made and increase the level of microanatomical knowledge in surgical treatment.Öğe Prevalence of flat foot among elementary school students, in rural and urban areas and at suburbs in Anatolia(Springer, 2011) Cetin, Aymelek; Sevil, Sedat; Karaoglu, Leyla; Yucekaya, BircanAbout 326 elementary school boys and 299 elementary school girls of an age ranging from 6 to 13 are included in this flat foot prevalence study. Results of the study are categorized in three groups, namely city centers, rural areas and suburbs. For the assessment of flat foot, footprint test is used. Prevalence of flat foot was 35.5% among girls and 28.5% among boys. Flat foot was associated with child age, residency and body mass index (BMI). Flat foot prevalence was highest among 6-year-old children, and lowest among 11-year and older children (P < 0.05). Flat foot prevalence was lower among children living in rural areas and children with low BMI value (P = 0.001). More overweight and at risk of overweight children had flat foot compared to normal and underweight children (P < 0.05). Familial predisposition was also noted for flat foot; 16.1% of children with flat foot had a familial history of flat foot, while this rate was only 5.6% in families of healthy subjects (P = 0.001).Öğe Sacrectomy Margins for Rectal Cancer Invading Sacrum: An Anatomic Study(Wiley-Blackwell, 2011) Aydin, Cemalettin; Kayaalp, Cuneyt; Cetin, Aymelek[Abstract Not Available]Öğe Ultrastructure of human umbilical artery and vein(2019) Cetin, AymelekAim: Our objective in this study was to investigate ultrastructure of endothelial and muscle cells of human umbilical vessels. Material and Methods: Ten umbilical cords were used for this study. These cords represented periods of gestation from sixteen weeks to full-term. The specimens were fixed in 5 % buffered glutaraldehyde for four hours at 4oC. The sections were postfixed for two hours in a solution of 1% osmium tetroxide prepared with Millonig phosphate buffer. Sections were dehydrated in ethanol and propylene oxide and then embedded in araldite. They were stained with uranyl acetate, examined electron microscopically. Results: Rod- shaped bodies were observed in the arterial endothelium in the early stage as described by Weibel-Palade. Large numbers of mitochondria and increased lipid and vacuoli structures and increased Weibel-Palade bodies were also noted in fullterm. the muscle cells of the umbilical vein were characterized by prominent crystalized structures of mitochondria at sixteen weeks.These structures were degenerated at full-term, and myelin figures were observed. Conclusion: The endothelial and muscle cells of the umbilical vessels from early stage to full-term showed morphological changes.
