Yazar "Cetin, Mustafa" seçeneğine göre listele
Listeleniyor 1 - 7 / 7
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Assessment of atrial electromechanical delay in patients with polycystic ovary syndrome in both lean and obese subjects(Wiley, 2014) Tasolar, Hakan; Mete, Turkan; Balli, Mehmet; Altun, Burak; Cetin, Mustafa; Yuce, Tuncay; Tasolar, SevgiAimEven though polycystic ovary syndrome (PCOS) is characterized by increased inflammatory activity and insulin resistance, there is no clinical data about whether risk of atrial fibrillation are increased in these patients. We aimed to evaluate atrial conduction parameters predicting atrial involvement in this patient group. MethodsThe study population comprised 50 women 18-40 years of age who had been diagnosed with PCOS. The patients were divided into two groups: lean women (L-PCOS) with a body mass index (BMI) under 25kg/m(2) and obese women (O-PCOS) with a BMI greater than 30kg/m(2). Twenty-five age-matched lean healthy women were enrolled voluntarily as the control group. Difference between maximum and minimum P-wave duration was calculated and was defined as P-wave dispersion (Pd). Inter- and intra-atrial electromechanical delays (inter-AED, intra-AED, respectively) were measured with tissue Doppler imaging. ResultsInter- and intra-AED parameters were higher in the L-PCOS group when compared with control subjects (anova, P=0.004 and P=0.013, respectively), and were also significantly higher in the O-PCOS group compared with other groups (anova, P<0.001 for both). The regression analyses indicated that Homeostasis Model of Assessment - Insulin Resistance (HOMA-IR) (=0.603, P<0.001) and BMI (=0.379, P<0.001) were the independent predictors of inter-AED, HOMA-IR (=0.835, P<0.001) was an independent predictor of intra-AED, and BMI (=0.457, P=0.006) and the left atrial diameter (=0.350, P<0.034) were independent predictors of Pd. ConclusionConsequently, our findings provide data regarding prolonged atrial conduction parameters in PCOS patients, especially when accompanied by obesity.Öğe Assessment of Diastolic Function with Mitral Annular Plane Systolic Excursion in Obese Adults(Elsevier Science Inc, 2013) Tasolar, Hakan; Mete, Turkan; Cetin, Mustafa; Altun, Burak; Balli, Mehmet; Bayramoglu, Adil; Otlu, Omur[Abstract Not Available]Öğe Blood urea nitrogen level in patients with chronic total occlusion predicts long-term mortality independent of estimated glomerular filtration rate and serum creatine level: (9-year follow-up results)(2021) Ozyildiz, Ali Gokhan; Cetin, Mustafa; Ozer, Savas; Duman, Hakan; Kiris, TuncayAim: Increased serum blood urea nitrogen (BUN) level is an indicator of neurohormonal and renal dysfunction, and is associated with the major adverse cardiovascular events (MACE). Chronic total occlusion (CTO) is a typical coronary artery disease diagnosed by coronary angiography. We established and tested the hypothesis that there might be a relationship between serum BUN level and long-term prognosis in patients with CTO. Materials and Methods: The study consisted of 124 patients diagnosed with CTO. The patients were followed up for a mean of 9.2 (7.4-9.5) years, and all-cause mortality was determined. Results: Patients were divided into two groups according to mortality outcome. During the follow-up, 38 of 124 patients died. Univariate Cox analysis showed that age (p=0.002), BUN (p=0.001), and serum creatinine levels (p=0.039) were associated with mortality. BUN level (OR: 1.074; 95% CI: 1.018-1.134; p=0.009) and age (OR: 1.043; 95% CI: 1.001-1.087, p=0.043) were independently associated with mortality in multivariate Cox analysis. In the ROC analysis, the AUC values for BUN and estimated glomerular filtration rate were 0.689 (p=0.002) and 0.650 (p=0.001), respectively. When the cutoff value for BUN level was considered >16 mg/dL, the sensitivity was 68%, and the specificity was 53% (OR:1.38) to predict mortality. When the cutoff value was considered >20 mg/dL, the sensitivity diminished to 40%, while the specificity increased to 90% (OR:3.9). Conclusion: In patients with CTO, BUN level is associated with increased all-cause mortality during long-term following. This relationship is independent of renal dysfunction.Öğe Effect of smoking on Tp-e interval, Tp-e/QT and Tp-e/QTc ratios as indices of ventricular arrhythmogenesis(Elsevier Science Inc, 2013) Tasolar, Hakan; Balli, Mehmet; Cetin, Mustafa; Altun, Burak; Cakici, Musa; Bayramoglu, Adil; Otlu, Omur[Abstract Not Available]Öğe Effects of Coronary Collateral Circulation on Tp-e interval, Tp-e/QT and Tp-e/QTc Ratios in Coronary Artery Disease Patients(Elsevier Science Inc, 2013) Tasolar, Hakan; Otlu, Omur; Bayramoglu, Adil; Balli, Mehmet; Cetin, Mustafa; Altun, Burak; Pekdemir, Hasan[Abstract Not Available]Öğe Phenotype frequencies of blood group systems and alloantibodies to red blood cells in blood transfusion recipients in Kayseri (Turkey)(2017) Altuner Torun, Yasemin; Kaynar, Leylagül; Karakukcu, Cigdem; Yay, Mehmet; Ergul, Ayse Betul; Turanoglu, Cem; Cetin, Mustafa; Eser, BülentAim: In this study, we aimed to asses the antigen and phenotype frequencies of various blood groups among recipients of erythrocyte suspensions in Kayseri. Material and Methods: The study was conducted as retrospective, cross sectional and multicenter study. In all, 48750 blood recipients old typed in terms of the ABO, Rh, MNS, Duffy, Lewis, P, Kell, Lutheran, and Kidd systems were subjected to erythrocyte phenotyping using a gel centrifugation method within the age group of 18-60 years. Results: Of the ABO blood group, A was most frequent (44%) followed by O, B, and AB (30.3%, 16.2%, and 6.5%, respectively). The frequencies of Rh antigens were 88% D-positive and 12% D-negative. Alloantibodies were detected by screening in 196 (0.4%) of 48,750 patients, and decreased in the order anti-E (62%), -C (43%), -D (42%), -C (11%), -c (11%), -e (8%), -M (7%), -Fy a (5%), -Jk a (5%), -Kp a (4%), -Le a (3%), -Jk b (2%) ,-S (2%), -Le b (1%), and -P (1%). The most frequently detected alloantibodies were anti-E (31.6%) and -K (21.9%). Conclusion: Knowledge of the phenotypic frequencies of red blood cell antigens allows the creation of banks of appropriate antigennegative blood, thus preventing transfusion reactions in patients requiring multiple transfusions or who express alloantibodies.Öğe Retrospective evaluation of patients with primary mediastinal large B-Cell lymphoma: Real life experience(2021) Guven, Zeynep Tugba; Celik, Serhat; Kaynar, Leylagul; Keklik, Muzaffer; Eser, Bulent; Cetin, Mustafa; Unal, AliAim: Primary mediastinal large B-cell lymphoma (PMBCL) is a type of lymphoma that forms approximately 3 % of non-Hodgkin lymphomas that often encounter with mass. The aim of this study was to present the epidemiological characteristics, response rates of the treatment and the survival of PMBCL patients in our single center. Materials and Methods: Patient demographics, treatment regimens, survival rates of PMBCL patients were retrospectively analyzed. Results: There are 15 patients in our study. Most of the patients were female (n:9, 60%). The median age at the time of diagnosis was 35.4. Nine patients applied with a bulky lesion in the mediastinum. Most of the patients have been treated with DA-EPOCH-R (dose-adjusted etoposide, doxorubicin, cyclophosphamide, vincristine and prednisone with rituximab) (n:13, 87%) and 2 (n:2, 13%) patients have been treated with R-CHOP (doxorubicin, cyclophosphamide, vincristine and prednisone with rituximab) regimens for 6 cycles. Eight patients (53.3%) received involved-field radiotherapy on the mediastinum. After the first-row chemotherapy, total remission rate was 93.3%. Thirteen (87%) of the patients were still in remission and alive. The median follow-up time in our study was 43 months (13 -81). Mean disease-free survival was 67.43 months and overall survival was 72.87 months. The overall and disease-free survival rate was 86.7 % and 80%. Conclusions: In our study, most patients responded to the treatment and are still being followed in remission.
