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Öğe Acute effect of moderate and high-intensity interval exercises on asprosin and BDNF levels in inactive normal weight and obese individuals(Nature Portfolio, 2023) Ceylan, Halil Ibrahim; Ozturk, Mehmet Ertugrul; Ozturk, Deniz; Silva, Ana Filipa; Albayrak, Mevlut; Saygin, Ozcan; Eken, OzgurThis study aimed to examine the acute effects of moderate-intensity aerobic and high-intensity interval exercise protocols on Asprosin and Brain-Derived Neurotrophic Factor (BDNF) levels in inactive normal weight and obese individuals. A total of 20 male individuals aged 18-65 years, ten normal weight (NW) (Body Mass Index (BMI): 18.5-24.99 kg/m(2)) and 10 obese (Ob) (BMI: 24.99-35.00 kg/m(2)) participated in this study, voluntarily. Moderate aerobic exercise (AE) (main circuit 30 min, between 40 and 59% of Heart Rate Reserve: HRR) and High-Intensity Interval exercise (HIIE) running protocols (main circuit 20 min, between 75 and 90% of the HRR for 1 min*10 times, and 1-min active rest at 30% of the HRR) was applied to the volunteer participants in the morning hours (08.00-10.00 a.m.), following the night fasting (at least 8-10 h) for at least 3 days between each other. Blood samples were collected from the participants before and immediately after each exercise protocol, and serum asprosin and BDNF hormone levels were determined by Enzyme-Linked Immunosorbent Assay method. Basal serum asprosin was found to be significantly higher in the Ob group compared to the NW group (p < .001), while the basal serum BDNF hormone was found to be lower (p < 0.05). It was observed that the serum asprosin level of both groups decreased significantly after both AE and HIIE protocols (p < 0.05). In addition, there was a significantly higher decrease in serum asprosin level in the Ob group compared to the NW group after HIIE protocol. For the Ob group, serum BDNF level increased considerably after HIIE protocol compared to AE protocol (p < 0.05). Serum asprosin was found to be higher in the Ob group, while the serum BDNF was found to be lower. In addition, the acute exercises of different intensity significantly affected hormones that regulate appetite metabolism. In particular, it was observed that the HIIE protocol had a greater effect on the regulation of appetite (hunger-satiety) in the Ob group. This result can be taken into account when planning training programs for these individuals.Öğe The Association of Gene Polymorphisms Linked to Caffeine Use with Athletic Performance(Gazi Univ, Fac Med, 2023) Yildirim, Selin; Bulgay, Celal; Ergun, Mehmet Ali; Eken, Ozgur; Ceylan, Halil Ibrahim; Nobari, Hadi; Cerit, MesutCaffeine's use as a performance-enhancing supplement among professional athletes progressively increased after it was taken off the World Anti-Doping Agency's (WADA) list of banned substances. The present review looks at the interactions caused by different levels of caffeine ergogenicity in athletes and gene polymorphisms that affect caffeine ergogenic effect in the current literature. Therefore, a comprehensive analysis of the studies available in the literature and the respective study results have evaluated caffeine ergogenicity in athletes and gene polymorphisms. The search for studies was performed through five databases. Individual responses to caffeine consumption may differ from person to person due to multigene and multifactorial interactions. Adenosine A2A receptor (ADORA2A) and Cytochrome P450 1A2 (CYP1A2) are two genes thought to have the most effects on caffeine's ergogenicity. The function of these two genes accounts for most inter-individual variations in studies after caffeine ingestion. Based on the findings, it is understood that the contribution of caffeine use to individual performance development varies over time due to changes in both environmental and epigenetic interactions, as well as parameters such as circadian rhythm, training loads, nutritional routine, habitual caffeine use, drug intake, expectation, time of consumption, and heredity. As a result, individual caffeine responses are highly complex and involve multiple modifiers.Öğe The effect of time of day on Special Judo Fitness Test in active judokas: Evaluation in terms of chronotype(Taylor & Francis Inc, 2024) Eken, Ozgur; Ceylan, Halil Ibrahim; Kurtoglu, Ahmet; Simenko, JozefThe present cross-sectional study aims to examine the effect of time of day on the judo-specific performance in judokas, considering their chronotypes. Twenty-four male judokas participated in the study where the Morningness-Eveningness Questionnaire was administered, and on it, they were divided into morning-type (MT:12-judokas) and evening-type groups (ET:12-judokas). Afterwards, the Special Judo Fitness Test (SJFT) was applied to both groups at three different times (morning: 09:00 h, afternoon: 13:00 h and evening: 17:00 h) with body temperature measured before and after every SJFT performance. As a result, the Group*Test Time interaction significantly affected overall throwing performance during SJFT [F(2,44) = 29.437, p = 0.001, eta 2p: .572]. Furthermore, a significant time effect was found for the SJFT index [F(2,44) = 5.118, p = 0.010, eta 2p: .189] and for the Group*Test Time interaction with the mean value of the index [F(2,44) = 24.424, p < 0.001, eta 2p: .526]. Furthermore, body temperature had a significant time effect [F(2,44) = 301.454, p < 0.001, eta 2p: .932] and the Group*Test Time interaction [F(2,44) = 5.802, p = 0.006, eta 2p: .209]. In conclusion, coaches and exercise experts should consider judo athletes' chronotype when planning special training programs to improve judo-specific anaerobic capacity. Furthermore, to minimize the impact of time of day and chronotype on athletes' performance in competitions, it is recommended that MT athletes develop their judo-specific anaerobic capacity in the evening hours, when their performance is lower, while ET athletes should do so in the morning hours when their performance is lower via randori training.Öğe Effects of different rest intervals in high intensity interval training programs on VO2max, body composition, and isokinetic strength and power(Mre Press, 2024) Kayhan, Recep Fatih; Bayrakdaroglu, Serdar; Ceylan, Halil Ibrahim; Eken, Ozgur; Bayrakdaroglu, Yesim; Badicu, Georgian; Al-Mhanna, Sameer BadriThe aim of this study was to evaluate the effect of 8 weeks of short and long rest running-based high-intensity training (HIIT) on body composition, isokinetic strength, and maximal oxygen uptake (VO2max). Nineteen physically active men were recruited to voluntarily participate in the study. The participants were grouped using the closed-envelope randomized method as HIIT with a short rest (HIITS, n = 9; age: 19.60 +/- 1.34 years) and HIIT with a long rest (HIITL, n = 10; age: 19.77 +/- 0.97). Pre and post the 8-week running-based HIIT program, body mass index and body fat % were measured and all subjects performed isokinetic strength tests to determine their hamstring (H)/quadriceps (Q) peak torque ratio and the peak power and peak work for their H and Q muscles. The participants also underwent a graded exercise test to determine their VO2max. Statistical analysis performed with One-Way Variance Analysis and Bonferroni correction post hoc tests. As a result of the study, there were no significant differences between the pre- and post-training isokinetic strength parameters for the H and Q of HIITL and HIITS at velocities of 60 and 240(degrees)s(-1). The VO2max did not change for HIITS training but the VO2max increased (p < 0.05) for HIITL training. In conclusion, that HIITL and HIITS programs for 8 weeks did not change the relative and absolute strength, force production and the VO2max, but the VO2max increased (p < 0.05) for HIITL training.