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Öğe ARE VESTIBULAR FUNCTION OR VISUOSPATIAL PERCEPTION AFFECTED IN INDIVIDUALS WITH IDIOPATHIC SCOLIOSIS?(Dokuz Eylul Univ Inst Health Sciences, 2025) Adli, Havva; Ramazanoglu, Engin; Candiri, Busra; Talu, Burcu; Coba, Idris; Aslanturk, Okan; Ceylan, Mehmet FethiPurpose: It was aimed to investigate the relationship between characteristics of the curve and balance, vestibular dysfunction, visuospatial perception, navigation performance, and quality of life in idiopathic scoliosis. Material and Methods: Thirty-three participants aged 10-25 were included. The Cobb angle of the participants was recorded. The degree of rotation of the curve with the mobile application called ScolioDetector; balance parameters with the duration of unipedal stance test (eyes open-closed, right-left foot, hard-soft ground); vestibular dysfunction with the Utenberger test; visual-spatial perception with the Corsi Block Tapping test; navigation performance with the triangle completion task; and quality of life was assessed with the Scoliosis Research Society-22. In the comparison made according to type and direction of scoliosis curve, analysis was performed with the independent sample t-test or Mann-Whitney U test; Pearson correlation or Spearman correlation test was used in the relationship between Cobb and rotation angle and other parameters. Results: In the comparison made according to the curve type, only the right eyes closed unipedal stance test duration (p=0.022) and Unterberger test rotation angle were found to be significantly different (p=0.045). According to the direction of the curve, except for the right foot unipedal stance test (eyes open) on soft ground (p=0.009) and Unterberger test displacement distance (p<0.05) and the degree of rotation with eyes open (p=0.007), no significant difference was found (p>0.05). A significant correlation was shown only between the rotation angle and the right foot eyes closed single leg stance test on soft ground. No significant correlation was found between Unterberger and Visual-Spatial Memory tests. Conclusion: The characteristics of the curve (C or S; right or left scoliosis) affect balance and vestibular dysfunction. The rotation angle is only related to balance; it was observed that the curve features were not associated with visuospatial perception and navigation performance.Öğe Cerebral palsy patient who developed mortal complications following hip surgery: A case report(Bayrakol Medical Publisher, 2024) Coban, Idris; Ceylan, Mehmet FethiPatients with cerebral palsy (CP) may develop complications such as infection or repeat dislocation following orthopedic surgery and rarely, mortal complications. A 7-year-old male CP patient underwent an iliac and femoral osteotomy due to a hip dislocation. Following the operation, the patient was discharged with a stable condition, but was admitted to the intensive care unit 3 days later after his clinical condition deteriorated. Detailed examination showed that the patient was experiencing hypovolemic shock due to gastrointestinal bleeding and died on the 3rd day of follow-up in the intensive care unit despite all revival efforts. In countries lacking hip follow-up programs, hip dislocations may be detected at a later period in CP patients. It should be noted that mortal complications may potentially develop in these patients after hip surgery. We presented this case report to put emphasis on these rare but serious complications.Öğe Comparison of lower extremity anthropometric measurements of healthy and pes planus patients in early adolescence(2020) Solgun, Selma; Çetin, Aymelek; Özbağ, Davut; Ceylan, Mehmet Fethi; Tanrıverdi, Cem GürkanAim: Pes Planus (PP) was defined as the decrease or loss of length of arcus longitudinalis medialis (MLA). The aim of the presentstudy is to find out whether PP causes any anthropometric changes in individuals and to determine the relationship between PP andfoot type.Materials and Methods: A total of 100 individuals, 50 PP patients (25 female and 25 male) and 50 healthy individuals (25 femaleand 25 male), between the ages of 11 and 14 were included. Circumference of waist, hip, thigh, leg, bimalleolar and foot; tarsaland MLA height; bimalleolar and foot breadth were measured. Leg index, foot index and foot types were calculated with variousanthropometric rates.Results: Significant differences were found in female circumference measurements of the waist, hip, both thighs and right footbimalleolar (P < .05). Significant differences were found in right and left foot bimalleolar circumferences measurements and legindexes in men (P < .05). Significant differences were found in both genders in right and left foot MLA and tarsal heights (P < .05).Conclusion: It was found that PP affects not only the foot anthropometric measurements but also the hip, thigh and leg measurements.Early treatment for PP can provide irreversible lower extremity problems that cause lower quality of life.Öğe The Effect of Sildenafil on Recuperation from Sciatic Nerve Injury in Rats(Galenos Publ House, 2016) Korkmaz, Mehmet Fatih; Parlakpinar, Hakan; Ceylan, Mehmet Fethi; Ediz, Levent; Samdanci, Emine; Kekilli, Ersoy; Sagir, MustafaBackground: Severe functional and anatomical defects can be detected after the peripheral nerve injury. Pharmacological approaches are preferred rather than surgical treatment in the treatment of nerve injuries. Aims: The aim of this study is to perform histopathological, functional and bone densitometry examinations of the effects of sildenafil on nerve regeneration in a rat model of peripheral nerve crush injury. Study Design: Animal experiment. Methods: The study included a total of thirty adult Sprague-Dawley rats that were divided into three groups of ten rats each. In all rats, a crush injury was created by clamping the right sciatic nerve for one minute. One day before the procedure, rats in group 1 were started on a 28-day treatment consisting of a daily dose of 20 mg/kg body weight sildenafil citrate given orally via a nasogastric tube, while the rats in group 2 were started on an every-other-day dose of 10 mg/kg body weight sildenafil citrate. Rats from group 3 were not administered any drugs. Forty-two days after the nerve damage was created, functional and histopathological examination of both sciatic nerves and bone densitometric evaluation of the extremities were conducted. Results: During the rotarod test, rats from group 3 spent the least amount of time on the rod compared to the drug treatment groups at speeds of 20 rpm, 30 rpm and 40 rpm. In addition, the duration for which each animal could stay on the rod throughout the accelerod test significantly reduced in rats from group 3 compared to rats from groups 1 and 2 in the 4-min test. For the hot-plate latency time, there were no differences among the groups in either the basal level or after sciatic nerve injury. Moreover, there was no significant difference between the groups in terms of the static sciatic index ( SSI) on the 42nd day ( p=0.147). The amplitude was better evaluated in group 1 compared to the other two groups ( p<0.05). Under microscopic evaluation, we observed the greatest amount of nerve regeneration in group 1 and the lowest in group 3. However, this difference was not statistically significant. Moreover, there was no significant difference in the bone mineral density (BMD) levels among the groups. Conclusion: We believe that a daily single dose of sildenafil plays an important role in the treatment of sciatic nerve damage and bone healing and thus can be used as supportive clinical treatment.Öğe The effectiveness of mobilization with movement on patients with mild and moderate carpal tunnel syndrome: A single-blinded, randomized controlled study(Hanley & Belfus-Elsevier Inc, 2023) Ceylan, Ismail; Buyukturan, Oznur; Aykanat, Omer; Buyukturan, Buket; Sas, Senem; Ceylan, Mehmet FethiStudy design: Single-blinded, randomized controlled study. Introduction: Carpal Tunnel Syndrome (CTS) causes pain and loss of function in the affected hand. The mobilization with movement (MWM) technique is a manual therapy method applied to correct joint movement limitation and to relieve pain and functional disorders. Purpose of the study: This study aimed to examine the effectiveness of MWM technique on pain, grip strength, range of motion, edema, hand reaction, nerve conduction, and functional status in patients with CTS. Methods: A total of 45 patients enrolled in the study. The MWM group ( n = 18) completed a 4-week combined conservative physiotherapy and MWM program, whereas the control group ( n = 18) received only the 4 weeks of conservative physiotherapy. Pain severity according to the numerical rating scale was used as primary outcome. Results: We found an improvement within the subjects in resting pain (MWMG:5.1 +/- 3.6 vs 1.1 +/- 2.4, Effect Size (ES) = 1.3; CG:4.5 +/- 3.3 vs 1.0 +/- 2.2, ES = 1.1), in activity pain (MWMG:6.5 +/- 3.7 vs 1.1 +/- 2.4, ES = 1.5; CG:4.8 +/- 3.4 vs 2.2 +/- 2.3, ES = 1) and in night pain (MWMG:5.9 +/- 3.2 vs 1.8 +/- 2.5, ES = 1.2; CG:5.3 +/- 4.2 vs +/- 2.3 +/- 3.5, ES = 0.9). For between the groups, a statistical difference was found for the activity pain, Disabilities of the Arm Shoulder and Hand Questionnaire score (MWMG:52.2 +/- 23.8 vs 27 +/- 24.7, ES = 1.3; CG:47.0 +/- 24.8 vs 41.5 +/- 22.1, ES = 0.2), Michigan Hand Outcomes Questionnaire (MHQ-1), (MWMG:44.4 +/- 23.7 vs 74.7 +/- 24.5, ES = 1.3; CG:44.8 +/- 17.4 vs 57.4 +/- 21.7, ES = 0.9) and MHQ-5 (MWMG:68.8 +/- 13.1 vs 82.5 +/- 11.5, ES = 0.9; CG:63.4 +/- 26.7 vs 59.3 +/- 25.8, ES = 0.1) parameters in favour of MWM group. Discussion: This study showed that MWM compared to conservative physiotherapy might be more effective in reducing perceived symptoms in mild and moderate CTS patients. Conclusions: MWM produced a small benefit to recovery of activity pain and upper extremity functionality level outcomes of patients with mild to moderate CTS when added to a traditional CTS physical therapy program. (c) 2023 Elsevier Inc. All rights reserved.Öğe Mini open surgical treatment of knee septic arthritis with local anesthesia: a prospective preliminary report(Derman Medical Publ, 2018) Ceylan, Mehmet Fethi; Guner, Savas; Turktas, Ugur; Ediz, Levent; Goktas, Ugur; Dogan, AliAim: Good pain management is provided via spinal and general anesthesia during knee joint drainage to treat septic arthritis, but the side effects are greater than those associated with local anesthesia, and the preparation process is long. Arthroscopic drainage under local anesthesia for knee septic arthritis treatment have been described, but this method requires special equipment. In this study, we aimed to evaluate the applicability of mini-open surgery under local anesthetic infiltration in cases of septic knee arthritis. Material and Method: 14 consecutive patients (eight men, six women) were admitted for knee septic arthritis treatment. Patient age ranged from 18 to 56 years, with an average age of 33 years. Drainage procedure was performed under local anesthesia, and the results were evaluated clinically. Results: The visual analog scale scores were between two and four (mean 2.8). The follow-up period was 10-21 months (mean 14.3). The Tegner and International Knee Documentation Committee scores were acceptable except for one patient. Discussion: This prospective study included mini-open surgery performed under local anesthesia on 14 septic knees, and showed that this method is safe, effective, well tolerated and be alternative to conventional techniques.Öğe Mini open surgical treatment of knee septic arthritis with local anesthesia: a prospective preliminary report(DERMAN MEDICAL PUBL, KARTALTEPE MAHALLESI, ATATURK BULVARI, ANKARA, 00000, TURKEY, 2018) Ceylan, Mehmet FethiAim: Good pain management is provided via spinal and general anesthesia during knee joint drainage to treat septic arthritis, but the side effects are greater than those associated with local anesthesia, and the preparation process is long. Arthroscopic drainage under local anesthesia for knee septic arthritis treatment have been described, but this method requires special equipment. In this study, we aimed to evaluate the applicability of mini-open surgery under local anesthetic infiltration in cases of septic knee arthritis. Material and Method: 14 consecutive patients (eight men, six women) were admitted for knee septic arthritis treatment. Patient age ranged from 18 to 56 years, with an average age of 33 years. Drainage procedure was performed under local anesthesia, and the results were evaluated clinically. Results: The visual analog scale scores were between two and four (mean 2.8). The follow-up period was 10-21 months (mean 14.3). The Tegner and International Knee Documentation Committee scores were acceptable except for one patient. Discussion: This prospective study included mini-open surgery performed under local anesthesia on 14 septic knees, and showed that this method is safe, effective, well tolerated and be alternative to conventional techniques.Öğe Periferik sinir iyileşmesi üzerine etil alkolün etkisi(İnönü Üniversitesi, 2006) Ceylan, Mehmet FethiPeriferik sinir iyileşmesinin uzun zaman aldığını bilmek çok önem- lidir. Bu çalışmada alkolik olan ve olmayan ratlar kullanıldı. Biz bu çalışmada; etanol kullanımının, periferik sinir iyileşmesi üzerine olan etkisini araştırmayı amaçladık. Gereç ve Yöntem: Bu çalışma; nönü Üniversitesi Deneysel Araştırma Merkezinde, 01/07/2004 ile 08/09/2004 tarihleri arasında yapıldı. Bu çalışma, bölgesel hayvanları koruma komitesi tarafından onaylandı. Deney materyali olarak 26 adet, 185-245 gr ağırlığında, yetişkin, sağlıklı, erkek, Wistar Albino cinsi rat kullanıldı. Yirmialtı adet Wistar Albino cinsi rat, rastgele 3 gruba ayrıldı. Birinci grup (n=6); yalnızca modifiye likid diyet alan, cerrahi yapılmayan grup, 2.grup(n=10); modifiye likid diyet alan ve periferik sinir tamiri yapılan grup, 3.grup(n=10); yal- nızca periferik sinir tamiri yapılan, alkol almayan grup olarak belirlendi. Tüm gruplara, sakrifiye edilmeden ve ameliyat öncesi EMG tetkiki yapıldı. Ameliyat sonrası 2. ayda, hayvanlar sakrifiye edildi ve sinir örnekleri histolojik tetkik için alındı. Bulgular: Yapılan EMG'lerde, tüm gruplar arasında önemli bir farklılığa rastlanmadı. Bununla beraber alkolik gruplarda, ılımlı aksonal dejenerasyona rastlanıldı. Sonuç: Periferik siniri tamir edilmiş alkolik ratlarda, periferik nöropatiye rastlanmadı. Bu çalışmada, hafif derecede alkol alımının bile periferik sinir hasarı yapabileceği gösterildi.Öğe Problems encountered in screening study with ultrasound for early diagnosis of developmental dysplasia of hip in eastern region of Turkey(Yuzuncu Yil Universitesi Tip Fakultesi, 2018) Ceylan, Mehmet Fethi; Korkmaz, Mehmet FatihThe aim of this study is to evaluate results of the screening program of the development al dysplasia of the hip (DDH) examined in newborn period. The problems encountered in the applicability of the early screening program were e valuated. By interviewing with the family of 1680 newborns born in our institution or referred, the information was given about the DDH and its risk factors, obtained results were recorded. The families were told to bring their babies for examination and hip ultrasound at the 3rd or 4th week of birth. In addition, all the parents were called by telephone the day prior to their appointments. Five hundred and thirty-six babies (31.3%) were brought to the first appointment. Forty-two hips (3.9%) of the 30 infants (5.6%) were detected as dislocated (Type 2c, D, 3). The 8 of these 30 patients (26.7%) whom the treatment was started were brought for the second control. Asymmetry of thigh folds was positive in the highest rate as the finding of the examination in the infants brought to the appointment. The rate of swaddling at the first appointment was found to be 74.2%. Surprisingly, less than one third of children were brought to ultrasound examination at first control. Similarly, about 3/4 of the parents continued to use swaddling for their babies. For the success of national DDH screening program, additional precautions must be taken to ensure the participation of the families and re lease of the swaddling.Öğe RIGHT LEFT DISCRIMINATION PERFORMANCE OF BODY PARTS IN INDIVIDUALS WITH SCOLIOSIS(Inonu University, 2024) Candiri, Büşra; Ramazanoğlu, Engin; Adli, Havva; Talu, Burcu; Çoban, İdris; Aslantürk, Okan; Ceylan, Mehmet FethiThis study aimed to examine the right-left discrimination of hands, feet and back in individuals with scoliosis. In the study, right-left discrimination performance was evaluated with the mobile application called Recognize, radiographic features of scoliosis were evaluated with X-ray, degree of rotation was evaluated with the mobile application called Scoliodetector, and back pain was evaluated with the Visual Analog Scale. 25 individuals with idiopathic scoliosis were included in the analysis. In the comparison made according to the thoracolumbar and lumbar curve, no difference was found between the groups in the lateralization performances (p>0.05). In the comparison according to the type of curve, no significant difference was observed in the reaction time and accuracy rate between the groups (p>0.05). When comparing the lateralization performance according to the direction of the curve, a significant difference was found between the groups in the left foot and back reaction times (p<0.05). Weak or very weak correlations were shown between Cobb and rotation angle and lateralization measurements of the back, hand and foot. It has been shown that the location and type of the curve (C or S) does not have a significant effect on lateralization performance in individuals with idiopathic scoliosis, however, the direction of the curve may affect the discrimination of right and left. © 2024, Inonu University. All rights reserved.Öğe Subdural hematoma and death due to unnoticed dural injury during spine surgery: A case report(Bayrakol Medical Publisher, 2020) Ceylan, Mehmet Fethi; Turkmen, Ersen; Durak, Mehmet AkifUnwanted dural injury in spinal surgery has been reported at varying rates and is seen extremely often. Death as a consequence of subdural hematoma following incidental dural injury is a very rare complication. The purpose of this study is to present a case of fatal subdural hematoma as a complication of dural injury which was not noticed during surgery. Here, we present a 40-year old female with congenital kyphosis of approximately 100 degrees at the T9-L2 level who underwent corrective spinal surgery in the form of laminectomy, foraminectomy, and partial corpectomy. The patient experienced a rapid deterioration in her level of consciousness and died within 3 days. We conclude that incidental dural injury which has not been noticed during the operation with subsequent subdural hematoma can be a fatal complication related to CSF leakage.Öğe The therapeutic efficacy of dexpanthenol on sciatic nerve injury in a rat model(Taylor & Francis Ltd, 2020) Korkmaz, Mehmet Fatih; Parlakpinar, Hakan; Erdem, Mehmet Nuri; Ceylan, Mehmet Fethi; Ediz, Levent; Samdanci, Emine; Kekilli, ErsoyObjective: The aim of this study was to evaluate histopathological, functional and bone densitometry examinations of the beneficial effects of dexpanthenol (DEX) on nerve regeneration in a rat model of peripheral nerve crush injury. Methods: Thirty adult Sprague-Dawley rats were divided equally into three groups. A crush injury was simulated in all rats by clamping the right sciatic nerve for one minute. In group 1, one day before the surgical procedure, 500 mg/kg DEX administered via intraperitoneally (ip) was initiated and continued three times in a week during the experiment period as 28 days. In group 2, rats received a dose of 10 mg/kg DEX to investigate possible effects of DEX alone. Group 3 served as the control (sciatic nerve injury) and was not given any drugs. Results: Performance was significantly lower in group 3 compared to the drug treatment groups during the rotarod test (30 rpm and 40 rpm) (p < 0.05). After a while, the rats which were able to remain on the rod was significantly lower in group 3 during the acceleration test (p < 0.05). Hot plate latency test results in group 3 were significantly lower when compared to the other groups (p < 0.05). Conclusion: DEX appears to be useful as a supportive clinical agent for the treatment of pain and nerve damage.
