Yazar "Ceyran, Ayse Bahar" seçeneğine göre listele

Listeleniyor 1 - 2 / 2
  • Küçük Resim
    Öğe
    Comparison of the microvessel density of gastric regions in normal and sleeve gastrectomized rats
    (2018) Orman, Suleyman; Yol, Sinan; Uzun, Huseyin; Ceyran, Ayse Bahar
    Aim: Background: The aim of this study is to compare the microvessel densities of different normal gastric regions and to determine the effects of sleeve gastrectomy on the microvessel density of tissues alongside the remnant stomach. Material and Methods: Twenty male Wistar albino rats were divided into two groups. Rats in the control group were immediately sleeve gastrectomized under anesthesia and a wedge resection of the esophagogastric junction (EGJ), the fundus, corpus and antral gastric regions was performed, before sacrifice. Meanwhile, rats in the experiment group also underwent sleeve gastrectomy but were not sacrificed until the 5th postoperative day. At this point, gastric tissues alongside the sleeve gastrectomy area were then wedge-resected. The microvessel densities of these two groups were evaluated and compared. Results: When comparing distinctive gastric regions within the control group, the microvessel density of the esophagogastric junction was found to be less than in the corpus or fundus (20.04±4.45; 36.28±9.98, 39.4±9.57; p <0.01). When comparing the control and experiment groups, No significant difference in the microvessel density of the esophagogastric junction was found (20.04 ± 4.45, 24.63 ± 8.91, p> 0.05). The sleeve gastrectomy also had no significant effect on the microvessel densities at the esophagogastric junction or corpus (24.63±8.91, 22.24±7,63; p> 0.05). Conclusion: The esophagogastric junction has a lower microvessel density than the corpus in a normal stomach. Sleeve gastrectomy has no adverse effect on the microvessel density of the esophagogastric junction.
  • Küçük Resim
    Öğe
    The role of histopathologic alterations of gallbladder wall in conversion cholecystectomy
    (2018) Orman, Suleyman; Ceyran, Ayse Bahar
    Aim: We aimed to investigate the role of histopathologic alterations of gallbladder wall in conversion cholecystectomy. Material and Methods: 3338 laparoscopic cholecystectomies and 121 conversion cholecystectomies that were performed between January 2008 and June 2017 in our hospital were evaluated. Patients were divided into 2 groups as laparoscopic and conversion cholecystectomy groups. Both groups were compared retrospectively by examining the histopathologic data of 140 patients were randomly analyzed. Results: There was a statistically significant difference between the types of surgery according to necrosis, polymorfonuclear leucocystes, mononuclear cells, edema levels (p <0.01). The incidence of polymorfonuclear leucocystes and mononuclear cells was at the marked and massive levels in cases with conversion cholecystectomy which were higher than in those with laparoscopic cholecystectomy. The rate of severe edema seen in conversion cholecystectomy was higher than in laparoscopic cholecystectomy (p <0.01). There was a statistically significant difference between the types of surgery according to granulation tissue, neoangiogenesis and fibroblast levels (p <0.01). There was a statistically significant difference between the necrosis-edema duple levels and Verhofstadt scores of the cases according to the operation type (p <0.01). Conclusion: Cholelithiasis histopathology that evaluates intra-mural factors has significant effects on conversion cholecystectomy with extra-mural factors. The increase in Verhofstadt score and Necrosis-Edema duple has been shown to increase the risk of conversion cholecystectomy surgery with great sensitivity. Preoperative superb microvascular imaging and contrast-enhanced ultrasound may helpful in detecting the necrosis and edema in the gallbladder wall which has also the potential to predict the risk of conversion cholecystectomy