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Öğe Clinical outcome of B2/C type isolated proximal LAD disease treated with drug-eluting stents(Aves Yayincilik, 2011) Cicek, Davran; Pekdemir, Hasan; Kalay, Nihat; Muderrisoglu, Haldun[Abstract Not Available]Öğe Efficacy of Sirolimus-Eluting Stents Compared With Paclitaxel-Eluting Stents in an Unselected Population With Coronary Artery Disease: 24-Month Outcomes of Patients in a Prospective Non-randomized Registry in Southern Turkey(Ivyspring Int Publ, 2010) Cicek, Davran; Pekdemir, Hasan; Kalay, Nihat; Binici, Sueleyman; Altay, Hakan; Muderrisoglu, HaldunBackground: The efficacy of drug-eluting stents has been shown in randomized trials, but some controversy exists regarding which stent sirolimus-eluting or paclitaxel-eluting is more effective in unselected Turkish patients. Therefore, we investigated the clinical outcomes of patients who were treated with one type of these drug-eluting stents in the real world. Methods: We created a registry and prospectively analyzed data on a consecutive series of all patients who presented to our institution with symptomatic coronary artery disease between February 2005 and March 2007 and who were treated with the sirolimus- or the paclitaxel-eluting stent. The follow-up period after stent implantation was approximately 24 months. The primary end point was a major cardiac event, and the secondary end point was stent thrombosis. Informed consent was obtained from all subjects, and the study protocol was approved by the local ethical committee. Results: In total, 204 patients were treated with either the sirolimus-eluting stent (n = 103) or the paclitaxel-eluting stent (n = 101). The lesions in the 2 arms of the study were treated similarly by conventional technique. At 24-month follow-up, patients who received the paclitaxel-eluting stent showed significantly higher rates of non-Q-wave myocardial infarction (1.9% vs 5.9%; P: .002), target vessel revascularization (1.9% vs 4.9%; P: .002), coronary artery bypass graft surgery (1.9% vs 6.9%; P: .001), and late stent thrombosis (1.9% vs 3.9%, P: .002). Conclusions: Patients who received the sirolimus- eluting stent showed better clinical outcomes compared with those who had the paclitaxel-eluting-stent.Öğe A Rare and Avoidable Complication of Percutaneous Coronary Intervention: Stent Trapped in the Left Main Coronary Artery and Its Unusual Treatment(Hellenic Cardiological Soc, 2011) Cicek, Davran; Pekdemir, HasanEntrapment of catheter components during cardiac interventions is rare but can cause life-threatening complications and sometimes requires emergency surgical treatment. This case study describes a 52-year-old male who had unstable angina pectoris and underwent stent insertion into the left circumflex artery. Unfortunately, the coronary stent and the balloon catheter were trapped while crossing the angulated segment between the left circumflex and left main coronary artery. The stent catheter was removed by an unusual transcatheter approach. The interventional cardiologist should keep in mind that angulated segments may reduce the successful rate of coronary stenting and contribute to the stent entrapment complication.Öğe TWO-YEAR OUTCOME OF TURKISH PATIENTS TREATED WITH ZOTAROLIMUS VERSUS PACLITAXEL ELUTING STENTS IN AN UNSELECTED POPULATION WITH CORONARY ARTERY DISEASE(Karger, 2010) Cicek, Davran; Pekdemir, Hasan; Kalay, Nihat; Binici, Suleyman; Altay, Hakan; Muderrisoglu, Haldun[Abstract Not Available]Öğe Two-year Outcome of Turkish Patients Treated with Zotarolimus Versus Paclitaxel Eluting Stents in an Unselected Population with Coronary Artery Disease in the Real World: A Prospective Non-randomized Registry in Southern Turkey(Ivyspring Int Publ, 2011) Cicek, Davran; Pekdemir, Hasan; Haberal, Cevahir; Kalay, Nihat; Binici, Suleyman; Altay, Hakan; Muderrisoglu, HaldunBackground: Our purpose was to investigate the clinical outcomes of Zotarolimus- and Paclitaxel-eluting stents in Turkish patients with coronary artery disease (CAD). In general, the outcome of drug-eluting stent (DES) placement has a proven efficacy in randomized trials. However, the difference in efficacy between the Zotarolimus and Paclitaxel-eluting stents in unselected Turkish patients is controversial. Therefore, we investigated the clinical outcomes of these two drug-eluting stents in the real-world. Methods: We created a registry and prospectively analyzed data on a consecutive series of all patients who presented to our institution with symptomatic coronary artery disease between February 2005 and March 2007 and who were treated with the zotarolimus- or the paclitaxel-eluting stent. The follow-up period was approximately two years. The primary end-point was major cardiac events, and the secondary end-point was definite stent thrombosis. Informed consent was obtained from all subjects, and the study protocol was approved by the local ethical committee. Results: In total, 217 patients were treated with either the zotarolimus-eluting stent (n = 116) or the paclitaxel-eluting stent (n = 101). The lesions in the 2 arms of the study were treated similarly by conventional technique. At 24-month follow-up the paclitaxel-eluting stent group showed significantly higher non-Q wave myocardial infarction (2.6% vs 5.9%, p: 0.02), Q wave myocardial infarction (1.7% vs 5.9%, p: 0.049), coronary artery binding graft surgery (2.6% vs 6.9%, p: 0.002), and late stent thrombosis (1.7% vs 3.9%, p: 0.046). Conclusions: Zotarolimus-eluting stents demonstrated better clinical outcomes than Paclitaxel- eluting stents in a daily routine practice of coronary intervention in an unselected Turkish population.