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Öğe Analysis of somatotype on liver, spleen and kidney morphology in healthy children: an ultrasonographic anatomy study(Cukurova Univ, Fac Medicine, 2025) Ulubaba, Hilal Er; Ciftci, Rukiye; Senol, Deniz; Toy, Seyma; Berk, Erhan; Uzun, Muhammet BoraPurpose: Somatotype is a quantitative expression of an individual's current morphological configuration and consists of three classifications: mesomorphy, endomorphy and ectomorphy. This study aimed to examine the relationship between somatotype and liver, spleen, and kidney morphometry in healthy children utilizing ultrasonographic (USG) methods. Materials and Methods: One hundred healthy children between the ages of 7 and 10 participated in the study. The sizes of liver, spleen and kidney were measured using USG. The children's somatotypes were determined according to the Heath-Carter method by taking 10 anthropometric measurements. Results: As a result of the measurements, it was determined that the highest value of liver length was 11.9 cm (9.9-13.6) in Mesomorph Endomorph somatotype and the smallest value was 10.9 (9-12.3) in central somatotype. The highest value of right kidney vertical length was 32 mm (25-45) in Mesomorph Endomorph somatotype and the lowest value was 29 mm (25-34) in central somatotype. According to the results of the Kruskall Wallis H test analysis, there was a statistically significant difference between liver length and right kidney vertical length measurements and somatotypes (p<0.05). Post-hoc analysis indicated that this difference was due to the central and mesomorph-endomorph somatotypes. Conclusion: In conclusion, we believe that our results should be taken into consideration for clinical diagnoses. Additionally, we suggest that taking our measurement results into consideration in abdominal ultrasound scans is necessary for an accurate evaluation. We think that clinicians evaluating the pathologies of diseases related to the organs we measured should not forget the size changes according to the somatotype results.Öğe Comparison of the Effects of the Somatotype on the Physical Activity, Kinesiophobia, and Fatigue Levels of Obstructive Sleep Apnea Syndrome Patients and Healthy Individuals(Iranian Scientific Society Medical Entomology, 2021) Toy, Seyma; Ciftci, Rukiye; Senol, Deniz; Kızılay, Fatma; Ermis, HilalBackground: We aimed to compare the physical activity, kinesiophobia, and fatigue levels of obstructive sleep apnea syndrome (OSAS) patients and healthy individuals in terms their somatotypes. Methods: A total of 165 individuals were enrolled referred to the Department of Chest Diseases Sleep Disorders Center Outpatient Clinic of Inonu University, Malatya, Turkey in 2018. The somatotype analysis was conducted using the Heath- Carter method, the fatigue level was assessed using the Functional Assessment of Chronic Illness Therapy (FACIT) fatigue scale, the kinesiophobia level was assessed using the Tampa Scale for Kinesiophobia (TSK), and the physical activity level was assessed using the International Physical Activity Questionnaire (IPAQ). Results: The results of the somatotype analysis revealed 3 different somatotypes in the healthy individuals and the OSAS patients' mesomorph endomorph, endomorphic mesomorph, and mesomorphic endomorph. When comparing the somatotypes of the healthy individuals and the OSAS patients, statistically significant differences were found in the FACIT scores of the mesomorph endomorphs, the IPAQ and FACIT scores of the endomorphic mesomorphs, and the TSK and FACIT scores of the mesomorphic endomorphs (P<0.05). Conclusion: In all three somatotypes of the OSAS patients, the fatigue index scores were higher when compared to those of the healthy individuals. Moreover, when compared with the healthy individuals, the physical activity levels of the endomorphic mesomorphs with OSAS were low, while the kinesiophobia scores of the mesomorphic endomorphs with OSAS were high. Based on the results of this study, in OSAS patients, the endomorphic mesomorph somatotype could be a risk factor for reduced physical activity, while the mesomorphic endomorph somatotype could be a risk factor for increased kinesiophobia.Öğe Deep learning for gender estimation using hand radiographs: a comparative evaluation of CNN models(Bmc, 2025) Ulubaba, Hilal Er; Atik, Ipek; Ciftci, Rukiye; Eken, Ozgur; Aldhahi, Monira I.BackgroundAccurate gender estimation plays a crucial role in forensic identification, especially in mass disasters or cases involving fragmented or decomposed remains where traditional skeletal landmarks are unavailable. This study aimed to develop a deep learning-based model for gender classification using hand radiographs, offering a rapid and objective alternative to conventional methods.MethodsWe analyzed 470 left-hand X-ray images from adults aged 18 to 65 years using four convolutional neural network (CNN) architectures: ResNet-18, ResNet-50, InceptionV3, and EfficientNet-B0. Following image preprocessing and data augmentation, models were trained and validated using standard classification metrics: accuracy, precision, recall, and F1 score. Data augmentation included random rotation, horizontal flipping, and brightness adjustments to enhance model generalization.ResultsAmong the tested models, ResNet-50 achieved the highest classification accuracy (93.2%) with precision of 92.4%, recall of 93.3%, and F1 score of 92.5%. While other models demonstrated acceptable performance, ResNet-50 consistently outperformed them across all metrics. These findings suggest CNNs can reliably extract sexually dimorphic features from hand radiographs.ConclusionsDeep learning approaches, particularly ResNet-50, provide a robust, scalable, and efficient solution for gender prediction from hand X-ray images. This method may serve as a valuable tool in forensic scenarios where speed and reliability are critical. Future research should validate these findings across diverse populations and incorporate explainable AI techniques to enhance interpretability.Öğe Deep Learning for Sex Estimation from Whole-Foot X-Rays: Benchmarking CNNs for Rapid Forensic Identification(Mdpi, 2025) Ciftci, Rukiye; Atik, Ipek; Eken, Ozgur; Aldhahi, Monira I.Background: Accurate sex estimation is crucial in forensic identification when DNA analysis is impractical or remains are fragmented. Traditional anthropometric approaches often rely on single bone measurements and yield moderate levels of accuracy. Objective: This study aimed to evaluate deep convolutional neural networks (CNNs) for automated sex estimation using entire foot radiographs, an approach rarely explored. Methods: Digital foot radiographs from 471 adults (238 men, 233 women, aged 18-65 years) without deformities or prior surgery were retrospectively collected at a single tertiary center. Six CNN architectures (AlexNet, ResNet-18, ResNet-50, ShuffleNet, GoogleNet, and InceptionV3) were trained using transfer learning (70/15/15 train-validation-test split, data augmentation). The model performance was assessed using accuracy, sensitivity, specificity, precision, and F1-score. Results: InceptionV3 achieved the highest accuracy (97.1%), surpassing previously reported methods (typically 72-89%), with balanced sensitivity (97.5%) and specificity (96.8%). ResNet-50 followed closely (95.7%), whereas simpler networks, such as AlexNet, underperformed (90%). Conclusions: Deep learning applied to whole-foot radiographs delivers state-of-the-art accuracy for sex estimation, enabling rapid, reproducible, and cost-effective forensic identification when DNA analysis is delayed or unavailable, such as in mass disasters or clinical emergency settings.Öğe Detection of common bile duct dilatation on magnetic resonance cholangiopancreatography by deep learning(Turkish Soc Radiology, 2025) Ulubaba, Hilal Er; Ciftci, Rukiye; Atik, Ipek; Karakul, Osman FurkanPURPOSE This study aims to detect common bile duct (CBD) dilatation using deep learning methods from artificial intelligence algorithms. METHODS To create a convolutional neural network (CNN) model, 77 magnetic resonance cholangiopancreatography (MRCP) images without CBD dilatation and 70 MRCP images with CBD dilatation were used. The system was developed using coronal maximum intensity projection reformatted 3D-MRCP images. The ResNet50, DenseNet121, and visual geometry group models were selected for training, and detailed training was performed on each model. RESULTS In the study, the DenseNet121 model showed the best performance, with a 97% accuracy rate. The ResNet50 model ranked second, with a 96% accuracy rate. CONCLUSION CBD dilatation was detected with high performance using the DenseNet CNN model. Once validated in multicenter studies with larger datasets, this method may help in diagnosis and treatment decision-making. CLINICAL SIGNIFICANCE Deep learning algorithms can aid clinicians and radiologists in the diagnostic process once technical, ethical, and financial limitations are addressed. Fast and accurate diagnosis is crucial for accelerating treatment, reducing complications, and shortening hospital stays.Öğe Evaluation of Willis Polygon Morphometry with Cranial Tomographic Angiography(Turkish Neurosurgical Soc, 2023) Ciftci, Rukiye; Cetin, Aymelek; Ulubaba, Hilal Er; Senol, Deniz; Cinarli, Fahri Safa; Ozbag, DavutAIM: To examine the morphometric properties of the vessels forming the Willis polygon (WP) in patients with type 2 diabetes mellitus (T2DM) and hypertension (HT) and compare them with healthy individuals.MATERIAL and METHODS: Cranial Tomography Angiography (CTA) of 168 individuals were analyzed retrospectively. The individuals included in the study were divided into four groups according to the diagnosis. Group 1 included 40 individuals who were diagnosed with HT, Group 2 included 43 individuals who were diagnosed with DM, Group 3 included 42 individuals who were diagnosed with DM and HT, and Group 4 was the control group and included 43 individuals. The diameter and length measurements of the vesselsRESULTS: According to the results of the Kruskal Wallis H test, in female patients statistically significant differences were detected in the diameter measurements of the right and left A1 segment of the ACA, the diameter measurement of the left A2 segment, the diameter measurements of the right and left P1 and P2 segments of the ACP, the diameter measurements of the right and left AComP. (p<0.05), in male patients statistically significant differences were found in the diameter of the right A1 segment of the ACA, the diameter and segment length measurements of the right and left P1 segments of the ACP, of the right and left P2 diameter measurements, and segment length measurements of the left AComP (p<0.05).CONCLUSION: We also found that the vessel diameters were similar in the HT, DM and HT+DM groups, and smaller than the control group. In addition, we think that knowing WP morphometric measurements will both guide the radio-anatomical evaluations to be made and increase the level of microanatomical knowledge in surgical treatment.Öğe Exploring the quadriceps muscle architecture variations in various sports disciplines: a comparative analysis of football, taekwondo, and athletics(Edizioni Minerva Medica, 2024) Ciftci, Rukiye; Kurtoglu, Ahmet; Car, Bekir; Karavas, Erdal; Eken, Ozgur; Soyler, Mehmet; Ardigo, Luca P.BACKGROUND: The purpose of this study was to comprehensively investigate and compare the architecture of the quadriceps muscle in football, taekwondo, and athletics, shedding light on potential differences and providing valuable insights for athletic training and performance enhancement. METHODS: Thirty-five athletes (football[N.]=14. [7 women, 7 men]; taekwondo [N.]=11. [6 women, 5 men]; athletics [N.]=10. [5 women, 5 men]) aged 17-21 years participated in the study. After participant demographic data were collected, 2D real-time B -mode ultrasound (USG) and right (R) and left (L) leg quadriceps muscle group rectus femoris (RF), vastus intermedius (VI), vastus lateralis, pennation angle (PA), RF cross-sectional area (CSA), and subcutaneous fat thickness were determined. RESULTS: In the study, in female athletes, R-RF+VI (P=0.04, ES:4.34), R -VI (P=0.01, ES: 6.1), R-RF: (P=0.009, ES: 7.9), R-CSA (P=0.04, ES: 5.2), L-RF (P=0.002, ES: 10.4) and L-CSA (P=0.007, ES: 7.7) significant differences were found in favor of the Football group. In male athletes, R-CSA (P=0.004, ES: 9.05), L-RF (P=0.05, ES: 3.5) and L-SFT (P=0.00, ES: 13.6), there was a significant difference in favor of the Football group. L -PA (P=0.009, ES: 6.2). L -PA (P=0.009, ES: 6.2) was significantly higher in the male Taekwondo group. CONCLUSIONS: Our research findings show that there is a significant relationship between the type of exercise performed and the structural differences observed in the quadriceps muscle. Consequently, it is highly recommended to consider the outcomes of our study for enhancing the efficacy of training programs in the domains of football, taekwondo, and athletics.Öğe Gonarthrosis related changes in quadriceps muscle architecture and physical function outcomes in women(Nature Portfolio, 2025) Ciftci, Rukiye; Kurtoglu, Ahmet; Eken, Ozgur; Aldhahi, Monira I.This study aimed to assess the effects of gonarthrosis on quadriceps muscle architecture and fatigue, physical function, and postural balance in women compared with healthy controls. Eighty-one females diagnosed with gonarthrosis (n = 40) and healthy control group (n = 41) aged between 47 and 77 years participated in the study. After demographic data were collected, right and left rectus femoris (RF), vastus intermedius (VI), vastus lateralis (VL) thicknesses and RF pennation angle (PA) were determined using a 2D real-time ultrasound device (USG). RF and VI depths and RF cross-sectional area (CSA) were obtained using ultrasound with the probe positioned in a transverse orientation to the muscle. In addition, the participants underwent the timed up and go test (TUG), 30-sec sit-and-up test (SU30s), and completed the Fatigue Severity Scale (FSS). The relationship between functional tests and right and left quadriceps muscle architecture parameters was also analyzed. In our study, the right CSA (p < .001, t=- 8.609, ES = 1.92), left VL (p = .020, t= - 2.365, ES = 0.052), and left CSA (p < .001, t=- 10.164, ES = 2.26) were significantly higher in the healthy group. Conversely, TUG (p < .001, t = 4.882, ES = 1.08) and FSS (p < .001, t = 10.362, ES = 2.29) were significantly higher in the gonarthrosis group, while SU30s values were higher in the control group (p < .001, t = - 12.262, ES = 2.73). Additionally, a negative correlation was observed between SU30s and CSA, whereas TUG and FSS showed a positive correlation with CSA (p < .001). According to the results of our study, some morphological losses were observed in the quadriceps muscle architecture of participants with gonarthrosis. Decreases in CSA affect functional performance. Determination of quadriceps muscle architecture in patients with gonarthrosis can be used to predict functional loss.Öğe Investigating the Impact of Body Composition Analysis on Quality of Life and Anxiety-Depression in Adult Males with Chronic Obstructive Pulmonary Disease(Mdpi, 2025) Kurtoglu, Ahmet; Eken, Ozgur; Ciftci, Rukiye; Cicek, Ipek Balikci; Durmaz, Dilber; Deniz, Mine Argali; Aldhahi, Monira I.Background/Objectives: Chronic obstructive pulmonary disease (COPD) is a progressive respiratory disorder characterized by systemic manifestations, including altered body composition, reduced quality of life, and psychological distress. Despite its significance, the relationship between body composition parameters and symptoms of fatigue, anxiety, and depression in patients with COPD remains underexplored. This study aimed to examine the association between detailed body composition metrics and quality of life, fatigue, and anxiety and depression symptoms in male patients with COPD compared to healthy controls. Methods: This cross-sectional study included 49 men with COPD and 51 age-matched healthy controls aged 50-80 years. Body composition was assessed using bioelectrical impedance analysis (BIA). Pulmonary function, dyspnea, activities of daily living, and psychological status were evaluated using spirometry, the Medical Research Council Dyspnea Scale, the London Chest Activity of Daily Living Scale (LCADL), and the Hospital Anxiety and Depression Scale (HADS), respectively. Results: Compared to the controls, patients with COPD exhibited significantly lower forced expiratory volume in one second (FEV1: 1.1 vs. 2.16 L; p < 0.001), lower fat mass (15.0 vs. 24.3 kg; p < 0.001), and higher muscle mass (53.8 vs. 42.0 kg; p < 0.001). They also reported significantly greater fatigue (Borg scale: 4 vs. 0; p < 0.001), higher anxiety (8 vs. 5; p = 0.006), and depression scores (11 vs. 5; p < 0.001), along with more pronounced limitations in their daily activities. Conclusions: COPD is associated with profound impairments in body composition, physical function, and mental health. Detailed body composition analysis using BIA provides valuable clinical insights and may aid in tailoring individualized interventions to improve quality of life and psychological outcomes in COPD management.Öğe Investigation of Factors Affecting Shuttle Walking Performance at Increased Speed for Patients with Chronic Obstructive Pulmonary Disease(Mdpi, 2023) Ciftci, Rukiye; Kurtoglu, Ahmet; Eken, Ozgur; Durmaz, Dilber; Eler, Serdar; Eler, Nebahat; Aldhahi, Monira I.The aim of this study was to examine the factors affecting the shuttle walking test (SWT) in patients with chronic obstructive pulmonary disease (COPD). A total of 29 patients with COPD (the COPD group) and a healthy group (HG) of 34 women aged between 55 and 74 years were included in the study. After the pulmonary function profiles of the participants were assessed, and the SWT was performed. Walking distances, walking speeds, and SWT levels (SWT-L) were determined with the SWT. Before and after the SWT, the heart rate (HR), oxygen saturation level (SPO2), and Borg scale (perceived exertion (BSe) and dyspnea (BSd)) results were analyzed with a paired sample t-test. The dyspnea levels during activity of daily living were determined with the Medical Research Council (MRC) dyspnea scale, and the relationship between MRC dyspnea (MRCD) and walking distance, speed, and SWT-L was tested using multiple linear regression and Pearson correlation analysis. The walking distance, speed, and SWT-L were lower in the COPD group (p < 0.001) than in the HG. The HR values before and after the SWT changed significantly in the COPD group and the HG (p< 0.001), and the effect size was higher in the COPD group. Although the BSe and BSd results before and after the SWT in the COPD group increased significantly (p < 0.001), they did not change in the HG. There was a highly negative correlation between MRCD and walking distance, speed, and SWT-L in the COPD group (p = 0.002, p = 0.000, and p = 0.001, respectively), but no correlation was found in the HG. The results showed that the HR, perceived exertion, and dyspnea levels of women with COPD whose respiratory functions were lower than the HG were significantly affected on the SWT.Öğe Investigation of Kidney Morphology and Somatotype Components in Early-Stage Kidney Patients(Kare Publ, 2023) Ulubaba, Hilal Er; Cinarli, Fahri Safa; Ciftci, Rukiye; Ulutas, OzkanObjectives: The aim of this study is to examine the kidney morphology and somatotype components of adult patients with early-stage chronic kidney disease (CKD). Methods: The sample consisted of 46 individuals with early-stage CKD (26 men and 20 women, mean age=45.92 +/- 16.53 years). The pathological subjects were compared with a control group consisting of 46 healthy subjects (28 men and 18 women, mean age=41.96 +/- 11.48 years). The Heath-Carter method was used to determine somatotype components. Abdominal computed tomography (CT) of patients with Stage 2 CKD and healthy volunteers taken within the past 3 months was scanned to determine kidney morphology. Kidney measurements were performed on CTs (length, width, depth, and volume of kidney). Results: Kidney patients (mean somatotype: 6.33-5.37-0.6) were less ectomorphic and more endomorphic than the controls (mean somatotype: 4.35-4.40-3.02). Moderate effect size (ES) was found in endomorphy (ES=0.87; p=0.035) and ectomorphy (ES=1.08; p=0.012) between groups. No significant difference was observed in the kidney morphology (ES=0.04-0.19; p>0.05). Conclusion: In the early-stage CKD, kidney morphology may not be the distinguishing factor. On the other hand, patients differed significantly in terms of endomorph components. Being overweight can also be one of the negative findings for kidney disease. Somatotype classification could be a suitable tool for monitoring kidney disease.Öğe Morphometric examination of the hepatobiliary duct system in healthy individuals and patients with cholelithiasis: A radio-anatomic magnetic resonance cholangiopancreatography study(Cukurova Univ, Fac Medicine, 2023) Toy, Seyma; Senol, Deniz; Ciftci, Rukiye; Sevgi, Serkan; Secgin, Yusuf; Yildirim, Ismail OkanPurpose: Cholelithiasis is a common gallbladder disease with high morbidity and treatment cost. Although the disease has many formation factors such as bile duct obstruction, congenital anomalies, genetic and metabolic diseases, the main cause is gallstones. The aim of this study is to examine the radio-anatomic and demographic characteristics of the bile ducts of patients who have cholelithiasis due to gallstones by using magnetic resonance cholangiopancreatography (MRCP) and to compare with healthy individuals.Materials and Methods: The study was carried out by retrospectively scanning the MRCP images of 113 patients diagnosed with cholelithiasis and 87 healthy individuals who were referred to the hospital for various indications and had no gallbladder pathology. Results: According to the Spearman rho correlation test performed by ignoring gender, a significant correlation was found between right hepatic duct diameter (RHD-D) and right hepatic duct - cystic duct angle (RHDCD-A), and between left hepatic duct diameter (LHD-D) and common bile duct diameter (CBD-D). In the correlation analysis performed only among males, a significant correlation was found between RHDCD-A and right hepatic duct - left hepatic duct angle (RLHD-A), RHDCD-A and common hepatic duct diameter (CHD-D) parameters. In the correlation analysis performed only among women, a significant relationship was found between age and RHD-D, LHD-D, CHD-D, CBD-D, between RHDCD-A and cystic duct - gallbladder angle (CDG-A), RHD-D, and between CHD-D and cystic duct diameter (CD-D).Conclusion: This study will contribute to literature by revealing the morphometric characteristics and radio -anatomic information of the hepatobiliary systems of both patients with cholelithiasis and healthy individuals.Öğe Morphometric Examinations of Internal Carotid Arteries of Patients with Hypertension and Patients with Type 2 Diabetes Mellitus: A Radio Anatomic Study Based on Computed Tomography Angiography Findings(Turkish Neurosurgical Soc, 2022) Ciftci, Rukiye; Ulubaba, Hilal Er; Senol, Deniz; Toy, Seyma; Yildirim, Ismail OkanAIM: To examine the relationship between the morphologic features of the internal carotid artery (ICA) and symptoms affecting cerebral blood circulation including type 2 diabetes mellitus (T2DM) and hypertension (HT).MATERIAL and METHODS: In this study, retrospective morphometric analysis of ICA measurements from 100 patients (aged 45-60 years) was performed using computed tomographic angiography (CTA) images. The images were divided into four groups: patients with HT (group 1), patients with T2DM (group 2), patients with HT and T2DM (group 3), and a healthy control group (group 4). Length and diameter measurements of the cervical, petrous, cavernous, and terminal segments of the ICA were made using 3D CTA images and recorded. The measurements of the male and female patients were compared using the Mann-Whitney U test and the groups were compared using the Kruskal-Wallis H test.RESULTS: It was found that there were statistically significant differences between male and female patients in terms of the right and left petrous, cavernous, and terminal segments of the ICA in group 1, right and left cervical left cavernous in group 3, left cervical, right and left petrous, cavernous, and right cavernous in group 4 (p<0.05). According to the Kruskal-Wallis H test analysis results, it was determined that there were no statistically significant differences between the patients in the four groups for all segment measurements (p>0.05).CONCLUSION: It was determined that ICA was more affected by HT than diabetes. In addition, we think that being knowledgeable of morphometric measurements of ICA will guide radio-anatomic evaluations and increase the level of microanatomic knowledge in surgical treatment.Öğe Morphometry of the Middle Cerebral Arteries: A Radio-Anatomical Study Based on Computed Tomography Angiography Findings(Soc Chilena Anatomia, 2023) Ciftci, Rukiye; Toy, Seyma; Ulubaba, Hilal Er; Senol, Deniz; Cinarli, FS.; Sigirci, AhmetMiddle cerebral artery (MCA), which has the largest irrigation area of the arteries that feed the brain, is an important artery whose microanatomy should be well known because of its vascular variation. In pathologies which are known to affect the cerebrovascular system such as type 2 diabetes mellitus (T2DM) and hypertension, morphometric characteristics of MCA gain importance. The aim of this study is to compare the morphometric characteristics of M1 segment of MCA in T2DM and hypertensive patients with those of healthy control group by using computed tomographic angiography (CTA). The study was carried out with retrospective morphometric analysis of CTA images of 200 individuals between 40 and 65 years of age. The individuals were grouped in four as hypertensive patients (group 1), patients with T2DM (group 2), patients with hypertension and T2DM (group 3) and healthy control group (group 4). Length and diameter measurements of M1 segment were performed and recorded by using 3D CTA images. While statistically significant difference was found between bilateral M1 segment diameters of both women and men (p<0.05), no statistically significant difference was found between segment lengths (p>0.05). As a result of the post hoc analysis performed, it was concluded that right and left M1 segment diameter of group 1, group 2 and group 3 was found to be different from group 4 in both sexes (p<0.05). We believe that this study will both be a guide in radio-anatomic assessments to be performed and also increase microanatomic level of information in the surgical treatment of the artery by showing the morphometric changes that occur in M1 segment of MCA in T2DM diseases.Öğe Quantitative Assessment of Extrinsic Tongue Muscle Stiffness in Obstructive Sleep Apnea Using Shear Wave Elastography(Mdpi, 2025) Ulubaba, Hilal Er; Dag, Nurullah; Tasolar, Sevgi Demiroz; Ciftci, Rukiye; Ermis, HilalBackground/Objectives: This study aimed to quantitatively and noninvasively evaluate the changes in the Genioglossus (GG) and Geniohyoid (GH) muscles in patients with Obstructive Sleep Apnea (OSA) using ultrasonography (US) and shear wave elastography (SWE). Methods: This prospective study included 94 adults (18-73 years) who underwent polysomnography (27 normal; 67 OSA). GG and GH muscle thickness was measured with US, and stiffness with SWE. Participants were grouped as non-OSA (Group 0) and OSA (Group 1). OSA patients were further divided by apnea-hypopnea index (AHI) into mild, moderate, and severe (Groups 1-3), forming four groups including controls. Results: No significant differences were observed in genioglossus or geniohyoid muscle thickness between groups. Shear wave elastography revealed significantly higher stiffness values for both the genioglossus and geniohyoid muscles bilaterally in OSA patients compared with non-OSA individuals (approximately 2.7 m/s vs. 2.4-2.5 m/s, p < 0.01). Geniohyoid muscle stiffness on both sides increased progressively with OSA severity, with significantly higher values in severe compared with mild OSA (p < 0.05). In contrast, genioglossus stiffness did not differ significantly across OSA severity subgroups. Conclusions: In patients with OSA, GH and GG muscle thickness remains unchanged, but their stiffness measured by SWE increases. GH stiffness also rises with increasing disease severity. These results indicate that GG and GH muscle stiffness may serve as useful noninvasive markers for OSA.Öğe Relationship between quadriceps muscle architecture and lower limb strength and physical function in older adults community-dwelling individuals: a cross-sectional study(Frontiers Media Sa, 2024) Cinarli, Fahri Safa; Ulubaba, Hilal Er; Ucar, Ozan; Kilinc, Deniz Can; Ciftci, Rukiye; Karayigit, Raci; Aldhahi, Monira, IBackground and objective: Factors related to muscle architecture may lead to functional limitations in activities of daily living in the older adults. This study aimed to investigate the relationship between quadriceps femoris (QF) architecture and physical function in older adults community-dwelling people. Methods: The study included 25 community-dwelling older adults participants aged over 60 years (14 women and 11 men) who were not engaged in regular physical activity. The rectus femoris (RF) and vastus intermedius (VI) muscle thicknesses as well as the RF cross-sectional area (CSA) were assessed using 2D ultrasonography. The 30 Seconds Chair Stand test (30sCST) and Timed Up and Go Test (TUG) were used to assess lower body muscle power and functional mobility, respectively. Results: The QF muscle architecture showed moderate and large correlations with the 30sCST (r range = 0.45-0.67, p < 0.05) and TUG (r range = 0.480-0.60, p < 0.05). RF thickness was a significant (p < 0.01) independent predictor of 30sCST (R-2 = 0.45) and TUG (R-2 = 0.36). VI thickness was a significant (p < 0.05) independent predictor of 30sCST (R-2 = 0.20) and TUG (R-2 = 0.231). RF CSA was a significant independent predictor of the 30sCST (R-2 = 0.250, p < 0.05) and TUG (R-2 = 0.27, p < 0.01). Multiple linear regression models explained 38% of the 30sCST variance and 30% of the TUG variance in the older adults group. Conclusion: Quadriceps muscle group directly affects basic activities of daily living in the older adults. Ultrasound measurements, which are non-invasive tools, are extremely valuable for understanding the limitations of activities of daily living in the older adults.Öğe Sex-Specific Associations Between 2D:4D Digit Ratio and Physical Fitness in Prepubertal Children: Evidence from Standardized Agility, Strength, and Endurance Assessments(Mdpi, 2025) Akgul, Fatih; Kurtoglu, Ahmet; Ciftci, Rukiye; Eken, Ozgur; Car, Bekir; Sanal, Alperen; Aldhahi, Monira I.Background: The second-to-fourth digit ratio (2D:4D) serves as a non-invasive proxy for prenatal androgen exposure. While its relationship with adult athletic ability is well documented, evidence for its association with childhood physical fitness remains inconsistent, and links between 2D:4D and objective fitness measures in prepubertal children are unclear. Methods: In this cross-sectional study, 338 prepubertal children (181 girls, 157 boys; aged 5-12 years) underwent precise measurement of right- and left-hand 2D:4D ratios (intra-class correlation coefficient = 0.94). Physical fitness was evaluated using standardized tests: the Illinois agility run, bent-arm hang, and standing long jump. Results: Among boys, higher 2D:4D ratios were modestly associated with prolonged bent-arm hang performance (beta = 0.19, q = 0.04) and shorter Illinois agility times (beta = -0.19, q = 0.04). No significant associations were observed in girls. All effect sizes were small, suggesting subtle, sex-dependent influences rather than robust predictors of performance. Conclusions: These findings indicate that prenatal hormonal environment may exert a limited, sex-specific influence on early physical fitness characteristics. Although biologically informative, the observed associations are insufficient for direct application in talent identification in sports. Longitudinal research incorporating direct hormonal measurements and broader populations is recommended to clarify developmental mechanisms and causal pathways.Öğe Somatotype Characteristics of Patients with Non-Dialysis Chronic Kidney Disease and its Relationships with Physical Activity and Depression(Soc Chilena Anatomia, 2022) Cinarli, Fahri Safa; Ciftci, Rukiye; Cinarli, Sena; Ulutas, OzkanSomatotype characters have been defined for many diseases. However, there is insufficient infonnation on the somatotype characters of chronic kidney patients. The first aim of our study was to define the specific somatotype in patients diagnosed with CKD. The second aim was to investigate the relationship between somatotype characters and physical activity and depression in CKD patients. A total of 88 (52.7 %) patients diagnosed with CKD between January and December 2021 at the Department of Nephrology, Inonu University Hospital (Malatya, Turkey) and 79 (47.3 %) healthy volunteers were included in the study. Somatotype analysis was performed using the Heath-Carter method. Physical activity was assessed with the International Physical Activity Questionnaire (IPAQ) and depressive symptoms with the Beck Depression Inventory (BDI). Analysis revealed that patients had greater medial calf girth (p = 0.036), higher triceps (p = 0.007) and suprailiac (p = 0.042) skinfold thicknesses and higher body mass index (p = 0.007) compared to controls. Patients also had significantly higher endomorphy (patients: 6.57 +/- 1.35 vs. controls: 6.04 +/- 1.3; effect size (ES): 0.40, p=0.010) and significantly higher mesomorphy (patients: 7.44 +/- 2 vs. controls: 6.85 +/- 2.3; ES: 0.27, p=0.039) as well as significantly lower ectomorphy (patients: 0.71 +/- 0.69 vs. controls: 1.10 +/- 0.93; ES: 0.47, p=0.006). Significant positive correlations were also observed between mesomorphy and IPAQ (rho = 0.219, p = 0.04), endomorphy and BDI (rho = 0.423, p < 0.001) and mesomorphy and BDI (rho = 0.392, p > 0.001). Significant negative correlations were observed between ectomorph and BDI (rho = -0.325, p = 0.002). We observed that the dominant somatotype was endomorphic mesomorph in patients with CKD. In addition, the fact that CKD patients with ectomorphic body structure have lower depressive symptoms could have an impact on their well-being.Öğe The effect of a combined exercise program on different surfaces on gastrocnemius muscle activation in young athletes(Bmc, 2025) Kurtoglu, Ahmet; Car, Bekir; Ciftci, Rukiye; Konar, Nurettin; Uzgur, Kamil; Eken, Ozgur; Ceylan, Halil IbrahimAim The aim of this study was to examine the effect of an exercise program (consisting of agility, balance, and coordination exercises) on the gastrocnemius muscle activation in young athletes on two different surfaces, sand (sea sand) and tartan (athletics track). Materials and methods Sixty-five young (15-17 years old) athletes (51% male, 49% female) were voluntarily included in this study. The participants were randomly divided into two groups as sand exercise group (SEG; n = 34) and tartan exercise group (TEG; n = 31). Participants were subjected to a 4-week (3 days) training program on the sand and tartan surfaces in addition to their normal athletic training. Participants were asked to perform an isometric plantar flexion movement at maximum strength with a stationary Active Force 2 hand dynamometer. During this movement, the participants'gastrocnemius muscle activation was determined using Neurotrac Myoplus Pro surface electromyography (sEMG) biofeedback device with electrodes placed on the gastrocnemius muscle before and after the 4-week training program. Results In the gastrocnemius muscle of the right leg, significant increases in average EMG activation were observed in the post-test compared to the pre-test (p < .05). The interaction groups*test duration had a significant effect on average value. Compared to SEG, it was observed that the average value increased significantly more in TEG after4 weeks. There was also a significant increase in interquartile range (IQR) and peak value in the post-test compared to the pre-test, regardless of the study groups (p < .05). For the left leg, the average, IQR, peak and power EMG activation increased significantly in the post-test compared to the pre-test, while the maximal voluntary contraction (MVC) value decreased significantly in the post-test compared to the pre-test (p < .05). Furthermore, the groups*test times interaction for all parameter values for the left leg was not statistically significant over the four weeks (p > .05). Conclusion Gastrocnemius muscle activation increased after the exercise program on both surfaces. However, results should be considered with caution, since not all the athletes have increased and not by the same magnitude.
