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Hypopituitarism in older adults: The report of five cases with different presentations
(2006) Cikim A.; Dikilitas M.; Cikim K.
Patients with hypopituatarism may present with many different signs and symptoms which result from reduced secretion of one or more of pituitary hormones. Severe hyponatremia and hypoglycemia are rare but potentially life threatening presenting clinical features of hypopituatarism. As these abnormalities are completely restored with replacement therapy and patients are often undiagnosed until admission, a high clinical suspicion is necessary to diagnose a patient with hypopituatarism. We present five cases exhibiting rare symptoms of hypopituatarism-severe hyponatremia, hypoglycemia and osteoporosis-as the only presenting feature; these cases illustrate that hypopituatarism must be considered in the differential diagnosis of these abnormalities, especially in older patients.