Yazar "Cinar, Tufan" seçeneğine göre listele

Listeleniyor 1 - 4 / 4
  • Küçük Resim
    Öğe
    Correlation of pulse oximetry oxygen saturation with blood gas arterial oxygen saturation in patients with heart failure reduced ejection fraction: Prospective cohort study
    (2020) Gok, Gulay; Cinar, Tufan; Nurkalem, Zekeriya; Duman, Dursun
    Aim: An estimation of accurate oxygen saturation is a critical in the management of patients with heart failure (HF). However, obtaining peripheral arterial blood samples may be technically difficult in some cases. The purpose of this study was to evaluate the correlation of pulse oximetry SO2 with arterial SO2 in patients with HF reduced ejection fraction (HFrEF). Material and Methods: In total, 29 consecutive patients who were admitted to cardiology clinics with HFrEF were prospectively enrolled in this study. We enrolled all patients if the chief physician ordered an atrial blood gas analysis. Simultaneous atrial blood gas sample and pulse oximetry measurements were collected and compared. The strength of association between atrial blood gas and pulse oximetry measurements was determined by Pearson correlation and Bland and Altman analysis.Results: We evaluated 29 heart failure patients (the mean age was; 70.7±10.9, 44.8 % of patients were male) with a mean EF of 29.6 ± 5.5. We observed that the mean pulse oximetry SO2 and arterial SO2 in the study were 92.8 ± 4.4 and 93 ± 5.2, respectively. We found significantly positive linear correlation between two methods according to Pearson analysis (r = 0.683, p 0.001). A low bias was found between two methods according to Bland and Altman method (-0.2296, p = 0.23).Conclusion: The present data may suggest that pulse oximetry oxygen saturation is an acceptable substitute for the arterial oxygen saturation in patients with HFrEF.
  • Küçük Resim
    Öğe
    Intra-aortic balloon pump-related thrombocytopenia: Its effects on in-hospital mortality in cardiogenic shock patients
    (2019) Hayiroglu, Mert Ilker; Cinar, Tufan; Tekkesin, Ahmet Ilker
    Aim: The present study aimed to evaluate the potential role of intra-aortic balloon pump (IABP)-related thrombocytopenia in patients with cardiogenic shock (CS) due to ST elevation myocardial infarction (STEMI) dien in hospital.Material and Methods: We retrospectively included 142 consecutive CS patients who were treated with IABP support from September 2013 to March 2017 in a tertiary heart center. IABP-related thrombocytopenia was defined as a platelet count of 150.000 mm3 or a 50% or greater reduction in the platelet count from the baseline following the IABP’s insertion. In-hospital, all-cause mortality was the primary endpoint.Results: The incidence rate of thrombocytopenia was 19% (n=27 patients). In-hospital mortality was significantly higher in patients who experienced thrombocytopenia compared to those who did not [22 patients (81.5%) vs. 56 patients (48.7%), respectively; p=0.004]. In a multivariate analysis, a decline in platelet count (OR: 1.037, 95%; CI: 1.011–1.064; p=0.005) was found to be independently associated with in-hospital mortality. In a receiver operating characteristic curve analysis, the optimal cut-off value of the decline in platelet count for the prediction of in-hospital mortality was ≥ 18.2%, with a sensitivity of 60% and a specificity of 77% [area under curve (AUC): 0.70, 95%; CI:0.61–0.78; p0.001].Conclusion: In the present study, we observed that the development of thrombocytopenia during IABP support was independently associated with in-hospital mortality in CS patients.Keywords: Intra-aortic balloon pump; thrombocytopenia; cardiogenic shock; in-hospital mortality.
  • Küçük Resim
    Öğe
    The predictive value of platelet to lymphocyte ratio for procedural complications and mid-term mortality in aortic stenosis patients who underwent a transcatheter aortic valve implantation
    (2019) Tosu, Aydin Rodi; Cinar, Tufan; Guler, Arda; Kahraman, Serkan; Gurbak, Ismail
    Aim: Calcific aortic valve disease is an active cellular process including chronic inflammation, calcification, and lipid accumulation which issimilar to atherosclerosis. The platelet to lymphocyte ratio (PLR) is a hematologicalparameter which increases with the inflammation and vascular oxidative stress. In the present study, we aimed to evaluate whether the PLR had a prognostic role inprocedural complications and mid-term mortality ofaortic stenosis (AS) patients underwent transcatheter aortic valve implantation (TAVI). Material and Methods: A total of 100 symptomatic severe AS patients undergone TAVI in atertiary heart center between June 2012 and June 2016 were retrospectively analyzed. The PLR was calculated by dividing the absolute platelet count by the absolute lymphocyte count before the TAVI procedure. The follow-up duration of the study was six months. Results: The mean age of study population was 78 years (range: 65-85), and 35 patients were male. Of note, serum PLR level was significantly elevated in patients who developed vascular complication and stroke after the TAVI (p<0.05, for all). In addition, the patients with a high serum PLR had an elevated mortality during six months’ follow-up (p<0.05). Conclusion: High pre-procedural PLR level may have a predictive value for vascular complications and stroke in AS patients who underwent TAVI. Particularly, patients with a high serum PLR values after the TAVI should be closely followed up because total mortality among these patients washigh.
  • Küçük Resim
    Öğe
    The predictive value of the shock index and modified shock index for the short-term mortality in patients with acute pulmonary embolism
    (2020) Cinar, Tufan; Oz, Ahmet; Efe, Suleyman Cagan; Altintas, Mehmet S; Ayca, Burak; Karabag, Turgut
    Aim: The purpose of the study was to examine the relationship of shock index (SI) and modified shock index (MSI) with pulmonary embolism severity index (PESI) score in predicting short-term death in acute pulmonary embolism (APE) patients. Material and Methods: This retrospective analysis included 104 consecutive patients whose APE was confirmed using computerized tomographic pulmonary angiography. For each patient, the PESI score, the SI, and the MSI were calculated. The main endpoint of the study was short-term mortality.Results: Patients based on hemodynamic status or the PESI score upon admission were allocated into high risk and non-high risk groups. We noted that SI and MSI were significantly elevated in a high risk group (1.17 ± 0.17 vs. 0.77 ± 0.17 and 1.54 ± 0.29 vs. 1.05 ± 0.21, respectively, p 0.001). In a correlation analysis, we showed that SI and MSI were significantly correlated with the PESI score for short-term mortality (r = 0.491 and r = 0.504, respectively, p 0.001). An area under curve value of SI and MSI for short-term death were 0.66 (0.52-0.79 95% CI, p = 0.022) and 0.67 (0.53-0.80 95% CI, p = 0.026) respectively.Conclusion: The present study findings demonstrated that the SI and MSI may be applicable in predicting short-death in patients with APE.