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Öğe Comparison of Results of Minimal Invasive Surgery for Pilonidal Sinus with Karydakis Procedure: Less is More(2017) Ozyildiz, Mehmet; Yazicioglu, Murat Burc; Coskun, Murat; Turgut, Hamdi Taner; Tiryaki, Çağrı; Civil, Osman; Yuksel, Adem; Yildiz, Selim YigitAim: Controversy still remains regarding the best surgical technique to use for the treatment of pilonidal disease to minimize disease recurrence and patient discomfort. Minimal surgical procedures can be performed on an outpatient basis. In this study, the early results of our minimally invasive operative approach cases are compared with Karydakis flap reconstruction results.Öğe Comprehensive analysis of impacts of lymph node yield on patient survival and recurrence in patients with stage II rectal cancer: A single institution study(2019) Civil, Osman; Okkabaz, Nuri; Sahin, Tevfik Tolga; Yazicioglu, Murat Burc; Tiryaki, Çağrı; Gunes, Abdullah; Ciftci, Ali; Aydin, DincerAim: Pathologic evaluation of rectal cancer is very important. Lymph node yields may be related to surgical technique or inadequate harvesting in the pathology department. The importance of lymph node yields >12 have been emphasized by many researchers to be adequate for staging. In stage II rectal cancer, the impacts of lymph node yield on locoregional recurrence and patient survival have not been studied. The aim of the present study is to evaluate the impact of lymph node yield on outcome and prognosis of the patients with stage II rectal cancer. Material and Methods: Patients with stage II rectal cancer who were operated in our institution between 2008 and 2013 were retrospectively analyzed to determine the impact of lymph node yield on survival, locoregional and distant metastasis.Results: Overall, local and distant recurrence rates were 13.9%, 4.65% and 9.30%; respectively. We did not find any significant difference in terms of locoregional and distant metastasis rates among Group I (lymph node12) (p>0.05). The 5-year survival of the patients in Group 1 versus Group 2 were 86.7% versus 82%; respectively (p>0.05). Conclusions: Results of the present study emphasize that lymph node yields may not have an impact on patient survival or recurrence. However, the patient groups were heterogeneous and the volume was low, therefore, more studies with higher volumes are needed. Keywords: Rectal Cancer; Staging; Lymph Node Metastasis.Öğe Comprehensive analysis of impacts of lymph node yield on patient survival and recurrence in patients with stage II rectal cancer: A single institution study(2019) Civil, Osman; Okkabaz, Nuri; Şahin, Tevfik Tolga; Yazıcıoğlu, Burc M.; Tiryaki, Çağrı; Güneş, Abdullah; Çiftci, AliAbstract: Aim: Pathologic evaluation of rectal cancer is very important. Lymph node yields may be related to surgical technique or inadequate harvesting in the pathology department. The importance of lymph node yields >12 have been emphasized by many researchers to be adequate for staging. In stage II rectal cancer, the impacts of lymph node yield on locoregional recurrence and patient survival have not been studied. The aim of the present study is to evaluate the impact of lymph node yield on outcome and prognosis of the patients with stage II rectal cancer.Material and Methods: Patients with stage II rectal cancer who were operated in our institution between 2008 and 2013 were retrospectively analyzed to determine the impact of lymph node yield on survival, locoregional and distant metastasis.Results: Overall, local and distant recurrence rates were 13.9%, 4.65% and 9.30%; respectively. We did not find any significant difference in terms of locoregional and distant metastasis rates among Group I (lymph node<12) and II (lymph nodes>12) (p>0.05). The 5-year survival of the patients in Group 1 versus Group 2 were 86.7% versus 82%; respectively (p>0.05).Conclusions: Results of the present study emphasize that lymph node yields may not have an impact on patient survival or recurrence. However, the patient groups were heterogeneous and the volume was low, therefore, more studies with higher volumes are needed.Öğe Evaluation of long-term oncological outcomes of colon cancer resections in octogenarian and nonagenarian patients(2020) Civil, Osman; Yazicioglu, M. BurcAim: To investigate the long-term oncologic results of patients older than 80 years who were operated on for colon cancer in our clinic. Material and Methods: All patients who were operated on for colon cancer in our clinic between 2006 and 2013 were included. Data were collected retrospectively by chart review. The final status of the patients was obtained by questionnaires answered by patients or patients’ relatives. Patients were divided into two groups according to their age, over 80 years of age and under 80 years of age, respectively. The following data were compared between groups; gender, pathological data, oncological treatment, one-year survival, disease-free survival and 5-year overall survival.Results: A total of 188 patients were included. There were 13 (6.9%) patients over 80 years of age. The expected 5-year survival rate under the age of 80 was 77.4%, while it was 46.2% for over the age of 80 (p = 0.001). The 5-year disease-free survival was calculated as 77% for under 80 years and 38.5% for over 80 years (p = 0.001). In the postoperative first year, 8 (4.6%) patients under 80 years of age and 1 (7.7%) of patients over 80 years of age died. Nine of 13 (69.2%) patients over 80 years of age died during follow-up.Conclusion: : In the light of the findings of our study, it can be said that the first 1-year survival rate of patients older than 80 years was similar to the younger patients, but they had worse survival rates in the longer term.Öğe Long-Term Results and Prognostic Significance of Non-ANATOMIC Liver Resection for Colorectal Liver Metastasis: Single Center Experience(Springer India, 2020) Civil, Osman; Okkabaz, Nuri; Sahin, Tevfik Tolga; Tiryaki, Cagri; Yazicioglu, Murat Burc; Kement, MetinDevelopment of liver metastasis is a single poor prognostic indicator if left untreated, and therefore management of colorectal liver metastasis (CRLM) is a subject of active multidisciplinary approach. We aimed to evaluate the long-term results and poor prognostic indicators in patients undergoing liver resection for CRLM from a single center in Turkey. All patients who underwent hepatic resection due to colorectal metastasis between March 2007 and November 2011 in our institute were included. Demographic data, operative and postoperative parameters, and long-term follow-up data were analyzed. A total of 44 patients [29 (65.9%) male, median age: 61 (32-81) years] were included to the study. Most of the patients [28 (63.6%) had metachronous liver metastasis, and almost half of the patients [19 (45.2%)] was oligometastatic. Major resection was performed in 18 (40.9%) patients. Intraoperative US changed the operative strategy in 7 (19.4%) patients. Thirty-day mortality was observed in 4 (9.1%) patients. Reasons for mortality were uncontrolled sepsis [catheter infection (n = 1), anastomotic leak (n = 1), and intraabdominal abscess (n = 1)] and hepatic insufficiency (n = 1). Follow-up period excluding patients with early mortality was 30.4 (3-138) months. Kaplan-Meier survival analysis revealed that estimated median survival time after hepatic resection was 28 (95% CI: 20.6-35.4) months. Five-year and 10-year survival probabilities were 20.5% and 13.3%, respectively. Multivariate Cox regression analyses showed that surgical margin positivity was the only significant factor affecting survival. Our results suggest that tumor margin and number of metastasis are the two determinant prognostic indicators in patients with CRLM. Surgery seems to offer a chance for cure, and surgeons in the field should try to perform liver resections in order to obtain negative margins. Major hepatic resections are justified provided that patient selection and preparation is thorough and surgical procedure can be performed safely.Öğe Solitary cecal diverticulitis, a rare cause of right lower quadrant pain: four cases(Kare publ, concord ıstanbul, dumlupınar mah, cıhan sk no 15, b blok 162 kadıkoy, ıstanbul, 00000, turkey, 2018) Yuksel, Adem; Civil, Osman; Colakoglu, Muhammed Kadri; Sumer, Fatih; Eruyar, Ahmet TugrulSolitary cecal diverticulitis is a rare clinical condition. Like diverticulitis in other segments of the colon, it requires immediate surgical intervention if it is causing complications. Solitary cecal diverticulitis may be misdiagnosed as acute appendicitis, since it causes right lower quadrant pain, or as a cecal tumor or inflammatory bowel disease, due to an intraoperative appearance resembling an inflammatory mass. Four patients with solitary cecum diverticulitis presenting with acute right lower quadrant pain are discussed in this report. Three patients underwent surgery with a preliminary diagnosis of acute appendicitis or cecal tumor, and 1 patient was diagnosed with cecal diverticulitis and treated medically. The treatment approach may change depending on a preoperative or intraoperative diagnosis of cecal diverticulitis. Therefore, in areas where this disease is uncommon, cecum diverticulitis should not be forgotten in the differential diagnosis of acute right lower quadrant pain or inflammatory bowel mass.Öğe Solitary cecal diverticulitis, a rare cause of right lower quadrant pain: Four cases(Kare Publ, 2018) Yuksel, Adem; Civil, Osman; Colakoglu, Muhammed Kadri; Sumer, Fatih; Eruyar, Ahmet TugrulSolitary cecal diverticulitis is a rare clinical condition. Like diverticulitis in other segments of the colon, it requires immediate surgical intervention if it is causing complications. Solitary cecal diverticulitis may be misdiagnosed as acute appendicitis, since it causes right lower quadrant pain, or as a cecal tumor or inflammatory bowel disease, due to an intraoperative appearance resembling an inflammatory mass. Four patients with solitary cecum diverticulitis presenting with acute right lower quadrant pain are discussed in this report. Three patients underwent surgery with a preliminary diagnosis of acute appendicitis or cecal tumor, and 1 patient was diagnosed with cecal diverticulitis and treated medically. The treatment approach may change depending on a preoperative or intraoperative diagnosis of cecal diverticulitis. Therefore, in areas where this disease is uncommon, cecum diverticulitis should not be forgotten in the differential diagnosis of acute right lower quadrant pain or inflammatory bowel mass.
